Risk factors and outcomes of postoperative stroke in surgical treatment for giant intracranial aneurysmsChinese Neurosurgical Journal - Tập 8 - Trang 1-9 - 2022
Hao Wang, Junlin Lu, Xin Chen, Qiang Hao
Giant intracranial aneurysms (GIAs) are challenges for surgical treatment. Risk factors of postoperative stroke remain unclear. This study aims to investigate the predictors of postoperative stroke in GIAs and the impact of stroke on outcomes. We performed a retrospective medical record review of patients with GIAs who received microsurgery at our institution between 2011 and 2018. Multivariate lo...... hiện toàn bộ
Primary gliosarcoma with widespread extracranial metastases—spatiotemporal morphological variationChinese Neurosurgical Journal -
Ming Luo, Jun Yang, Jianjun Sun, Fengyun Wang, Xiaodong Chai
Abstract
Background
We summarize 5 cases of primary gliosarcoma with widespread extracranial metastases including our case. The glial components are eliminated due to the needs of the living environment in the process of parasitism and survival of brain glioma-sarcoma cells in lung metastasis.... hiện toàn bộ
Comparative omics of CCM signaling complex (CSC)Chinese Neurosurgical Journal - Tập 6 - Trang 1-11 - 2020
Johnathan Abou-Fadel, Mark Smith, Kamran Falahati, Jun Zhang
Cerebral cavernous malformations (CCMs), a major neurosurgical condition, characterized by abnormally dilated intracranial capillaries, result in increased susceptibility to stroke. KRIT1 (CCM1), MGC4607 (CCM2), and PDCD10 (CCM3) have been identified as causes of CCMs in which at least one of them is disrupted in most familial cases. Our goal is to identify potential biomarkers and genetic modifie...... hiện toàn bộ
Pedicle screw accuracy assessment in ExcelsiusGPS® robotic spine surgery: evaluation of deviation from pre-planned trajectoryChinese Neurosurgical Journal - Tập 4 - Trang 1-6 - 2018
Bowen Jiang, A. Karim Ahmed, Corinna C. Zygourakis, Samuel Kalb, Alex M. Zhu, Jakub Godzik, Camilo A. Molina, Ari M. Blitz, Ali Bydon, Neil Crawford, Nicholas Theodore
The ExcelsiusGPS® (Globus Medical, Inc., Audubon, PA) is a next-generation spine surgery robotic system recently approved for use in the United States. The objective of the current study is to assess pedicle screw accuracy and clinical outcomes among two of the first operative cases utilizing the ExcelsiusGPS® robotic system and describe a novel metric to quantify screw deviation. Two patients who...... hiện toàn bộ
Clinical characteristics and survival of glioblastoma complicated with non-central nervous system tumorsChinese Neurosurgical Journal - Tập 8 - Trang 1-6 - 2022
Chen Wang, Di Wang, Changqing Pan, Jiazheng Zhang, Cheng Cheng, You Zhai, Mingchen Yu, Zhiliang Wang, Guanzhang Li, Wei Zhang
Diagnosis and treatment of patients with glioblastoma (GBM) who are also diagnosed with primary non-central nervous system (CNS) tumors remain a challenge, yet little is known about the clinical characteristics and prognosis of these patients. The data presented here compared the clinical and pathological features between glioblastoma patients with or without primary non-CNS tumors, trying to furt...... hiện toàn bộ
HOXC8: a predictive glioma biomarker that induces epithelia-mesenchymal transitionChinese Neurosurgical Journal - - 2018
Tingyu Liang, Xiaoxuan Wang, Peiliang Li, Yang Cao, Enshan Feng, Gan You
The transcription factor Homeobox C8 (HOXC8) is overexpressed and regulates many important genes involved in the proliferation and invasion of many malignant tumors. However, the function of HOXC8 in gliomas remains unclear. Based on the Chinese Glioma Genome Atlas (CGGA) set, HOXC8 expression is negatively correlated with overall survival (OS). Small interfering RNA (si-HOXC8) was used to downreg...... hiện toàn bộ