Chinese Journal of Cancer Research
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Sắp xếp:
The modified radioimmunoassay of serum inhibin and its value in monitoring ovarian tumor
Chinese Journal of Cancer Research - Tập 11 - Trang 142-146 - 1999
Objectives and Methods: A modified radioimmunoassay (RIA) of serum inhibin (INH) was developed and applied to measure serum INH contents in 39 fertile and 16 postmenopausal women. Thirty-three cases of ovarian tumors, including granulosa cell tumors and other kinds of ovarian tumors, were monitored by serum INH RIA. Results: The mean value of serum INH contents in follicular, peri-ovulatory and mi......
Experiment studies of antitumor proliferation and metastasis of a new chinese herb AT-1
Chinese Journal of Cancer Research - Tập 15 - Trang 223-226 - 2003
Objective: To study the effects of a new Chinese herb AT-1 on the tumor cell proliferation and metastasis in vitro. Methods: Tumor cell proliferation activity was tested by MTT. The ability of tumor cell invasion and migration was assayed by counting the number of tumor cells going throw matrigel. The expression changes of CD44 genes in PG cells treated with AT-1 were tested by FACS. Results: Comp......
A method to generate mature dendritic cells from cryopreserved PBMC
Chinese Journal of Cancer Research - Tập 15 - Trang 9-13 - 2003
Objective: To established methods for cryopreserving peripheral blood mononuclear cells (PBMCs) and producing DCs from cryopreserved PBMCs. Methods: Mature DCs were generated from cryopreserved PBMCs by using IL-4, GM-CSF, TNF-α, IL-1β, IL-6, pgE2 and LPS. The phenotype of the resultant DCs was investigated by flow cytometry. The functions of the resultant DCs were verified by Elispot assay. Resul......
Susceptibility to allitridi of Helicobacter pylori with different genotypes in gastric diseases
Chinese Journal of Cancer Research - Tập 20 - Trang 268-273 - 2009
To investigate the difference in susceptibilities to allitridi of Helicobacter pylori (H.pylori) strains in different gastric diseases and the associations with different genotypes.
H.pylori strains were isolated from gastric antral biopsy specimens and identified. DNA was isolated from H.pylori strains. Different genotypes were determined by polymerase chain reaction(P......
C-erbB-2, p53, N-ras expression in hepatocellular carcinoma
Chinese Journal of Cancer Research - Tập 8 - Trang 178-182 - 1996
To assess the relationship between C-erbB-2, p53, N-ras status at a premalignant stage and in HCC, the authors studied the imunohistological expression of these genes in HCC, liver cirrhosis and in the adjacent normal resected liver tissue, using monoclonal antibody to mutated p53 and activated C-erbB-2, N-ras. C-erbB-2 was expressed in 97.1% (35/36) of HCC and 100% (18/18) of hepatic cirrhosis, l......
Promotion of chemical carcinogenesis and P53 expression by reduction of superoxide dismutase activity in the lung of ratin vivo
Chinese Journal of Cancer Research - Tập 7 - Trang 10-14 - 1995
In the present experiment, an inhibitor of superoxide dismutase (SOD), diethyldithiocarbamate (DETC), was used to decrease SOD activity for the observation of the relation between SOD activity and carcinogenesis and the expression of P53 proteinin vivo. 144 Wistar rats were used for the present study. The results showed that the SOD activity reduction by DETC resulted markedly in the promotion of ......
Comparative study of images with pathology: Superparamagnetic iron oxide-enhanced magnetic resonance image (MRI) of splenic VX2 tumor in rats
Chinese Journal of Cancer Research - Tập 20 - Trang 26-32 - 2008
To establish a rodent model of VX2 tumor of the spleen, to analyze relationship between the change of the signal intensity on superparamagnetic iron oxide enhanced magnetic resonance image (MRI) and pathologic change to evaluate the ability of superparamagnetic iron oxide enhanced MRI for detection of splenic metastases. 8 rodent models of VX2 tumor of spleen were established successfully. The ima......
Genetic instability in cervical carcinoma
Chinese Journal of Cancer Research - Tập 14 - Trang 246-250 - 2002
Objective: The role of human papillomavirus (HPV) in the development of cervical carcinoma has been clearly established but other factors could be involved in cervical tumorigenesis such as loss of heterozygosity (LOH) and microsatellite instability (MI). The aim of the present study was to investigate the genetic instability in cervical carcinoma tissues and provide evidence for discovering new t......
The effect of RNAi-mediated gene silencing on her-2/neu gene expression in lung adenocarcinoma cells
Chinese Journal of Cancer Research - Tập 17 Số 2 - Trang 84-89 - 2005
Apoptosis và sự sinh trưởng của tế bào u trong ung thư cổ tử cung giai đoạn tiến triển địa phương sau hóa trị liệu nội động mạch tiên quyết Dịch bởi AI
Chinese Journal of Cancer Research - Tập 15 - Trang 227-231 - 2003
Mục tiêu: Thông qua việc quan sát phản ứng lâm sàng với hóa trị liệu nội động mạch tiên quyết ở bệnh nhân ung thư cổ tử cung giai đoạn tiến triển địa phương và điều tra sự thay đổi của biểu hiện protein p53, sự sinh trưởng và apoptosis của tế bào u sau hóa trị, nhằm nghiên cứu mối quan hệ giữa các dấu ấn sinh học và phản ứng hóa trị. Phương pháp: 20 phụ nữ mắc ung thư cổ tử cung tế bào vảy giai đo......
#hóa trị liệu #ung thư cổ tử cung #apoptosis #p53 #chỉ số sinh trưởng
Tổng số: 1,071
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