Chimia
SCIE-ISI SCOPUS (1947-1949,1960-1961,1973-1986,1996-2023)
0009-4293
0009-4293
Thụy Sĩ
Cơ quản chủ quản: SWISS CHEMICAL SOC , Swiss Chemical Society
Lĩnh vực:
Chemistry (miscellaneous)Medicine (miscellaneous)
Các bài báo tiêu biểu
The Synthetic Development of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu®): A Challenge for Synthesis & Process Research
The evolution of the synthesis of oseltamivir phosphate (Tamiflu®), used for the oral treatment and prevention of influenza virus infections (viral flu) is described. Oseltamivir phosphate is the ethyl ester prodrug of the corresponding acid, a potent and selective inhibitor
of influenza neuraminidase. The discovery chemistry route and scalable routes used for kilo laboratory pro... ...
Tập 58 Số 9 - Trang 621
Porous Coordination Polymers as Novel Sorption Materials for Heat Transformation Processes
Porous coordination polymers (PCPs)/metal-organic frameworks (MOFs) are inorganic–organic hybrid materials with a permanent three-dimensional porous metal–ligand network. PCPs or MOFs are inorganic–organic analogs of zeolites in terms of porosity and reversible guest
exchange properties. Microporous water-stable PCPs with high water uptake capacity are gaining attention for low t... ...
Tập 67 Số 6 - Trang 419
Molecular-Based Magnetism in High-Spin Molecular Clusters and Three-Dimensional Networks Based on Cyanometalate Building BlocksThe field of molecule-based magnets is a relatively new branch of chemistry, which involves the design and study of molecular compounds that exhibit a spontaneous magnetic ordering below a critical temperature, Tc. One major goal involves the design of materials with tuneable Tc's for specific applications in memory storage devices. Molecule-based magnets with high magnetic ordering temper... ...
Tập 54 Số 10 - Trang 593
Applications of Click Chemistry in Radiopharmaceutical Development
Click chemistry, a concept that employs only practical and reliable transformations for compound synthesis, has made a significant impact in several areas of chemistry, including material sciences and drug discovery. The present article describes the use of click chemistry for the development
of radiopharmaceuticals. Target templated in situ click chemistry was used for lead gene... ...
Tập 64 Số 1-2 - Trang 29
iMatrixSpray: A Free and Open Source Sample Preparation Device for Mass Spectrometric Imaging
A device was built for matrix deposition in mass spectrometric imaging. This spray-type instrument requires no user interaction other than providing the spray solution and selecting the pre-defined or custom-built method. Robustness was achieved by utilizing a delta-robotics design
in combination with a simple liquid system. All the information describing the systems is provided ... ...
Tập 68 Số 3 - Trang 146
Probing Colloidal Particle Aggregation by Light Scattering
The present article reviews recent progress in the measurement of aggregation rates in colloidal suspensions by light scattering. Time-resolved light scattering offers the possibility to measure absolute aggregation rate constants for homoaggregation as well as heteroaggregation processes.
We further discuss the typical concentration dependencies of the aggregation rate constants... ...
Tập 67 Số 11 - Trang 772
Hydrogen Activation by Benzene-Ruthenium Complexes in Aqueous Solution: Synthesis, Molecular Structure, and Intercalation of the Cluster Cation [{C₆H₆)₄Ru₄H₄]²⁺The hydrogenation of the aqua complex [(C6H6)Ru(H2O)3]2+, prepared in situ by hydrolysis of (C6H6)2Ru2Cl4 in water, was found to lead to the tetranuclear cluster dication [(C6H6)4Ru4H4]2+ (1) which crystallizes as the dichloride from the aqueous solution. In the presence of acetate ions, however, the reaction yields the dinuclear cations [(C6H6)2Ru2H(OOCCH3)X]+ (X=OH: 2, X=Cl: 3) which cry... ...
Tập 47 Số 6 - Trang 189
The Application of Electrospun Titania Nanofibers in Dye-sensitized Solar Cells
Titania nanofibers were fabricated using the industrial NanospiderTM technology. The preparative protocol was optimized by screening various precursor materials to get pure anatase nanofibers. Composite films were prepared by mixing a commercial paste of nanocrystalline anatase
particles with the electrospun nanofibers, which were shortened by milling. The composite films were se... ...
Tập 67 Số 3 - Trang 149
Development of [18F]-PSS223 as a PET Tracer for Imaging of Metabotropic Glutamate Receptor Subtype 5 (mGluR5)
Involvement of metabotropic glutamate receptor subtype 5 (mGluR5) in physiological and pathophysiological processes in the brain has been demonstrated, and hence mGluR5 has emerged as an important drug target. [11C]-ABP688 is clinically the most successful mGluR5 positron
emission tomography (PET) tracer to date and it allows visualization and quantification of mGluR5. Due to the... ...
Tập 66 Số 4 - Trang 201
Improving Sensitivity of Solid-state NMR Spectroscopy by Rational Design of Polarizing Agents for Dynamic Nuclear Polarization
We review our recent efforts to optimize the efficiency of polarizing agents for Dynamic Nuclear Polarization (DNP) in solid-state MAS NMR spectroscopy. We elucidate the links between DNP performance, molecular structure and electronic relaxation properties of dinitroxide biradicals.
We show that deuteration and increased bulkiness lead to slower electronic relaxation and in turn... ...
Tập 71 Số 4 - Trang 190