Fluorinated tetraketone derivatives of N-substituted carbazoles and their Eu(III) complexes for fluorescence immunoassayChemistry of Heterocyclic Compounds - Tập 54 - Trang 528-534 - 2018
Dmitriy E. Pugachov, Tatiana S. Kostryukova, Georgy V. Zatonsky, Sergey Z. Vatsadze, Nikolai V. Vasil’ev
New fluorinated tetraketone derivatives of N-substituted carbazoles were synthesized and tested as ligands for fluorescence immunoassay. The spectral properties of the obtained heterocyclic tetraketones and their Eu(III) complexes were studied. The complexes showed longwave absorption at 360–380 nm, high extinction coefficient values, long lifetime of excited states, and intense luminescence, allo...... hiện toàn bộ
Synthesis and antitumor activity of 3-[(methyl)bis(5-trialkylsilyl-furan-2-yl)silyl]propylaminesChemistry of Heterocyclic Compounds - Tập 47 - Trang 1502-1508 - 2012
L. Ignatovich, V. Romanov, J. Spura, J. Popelis, I. Domracheva, I. Shestakova
Novel 3-[(methyl)bis(5-trialkylsilylfuran-2-yl)silyl]propylamines have been synthesized by a hydrosilylation reaction of aliphatic and heterocyclic N-allylamines in the presence of the Speier's catalyst. The effects of the structure of the amine and the alkyl substituent at the silicon atom on the cytotoxicity of the compounds have been studied.
Condensed Isoquinolines. 12. Synthesis of Novel Heterocyclic Systems Containing a Partially Hydrogenated Spiro[isoquinoline-4,4'-(2H)-pyran] FragmentChemistry of Heterocyclic Compounds - Tập 38 - Trang 300-305 - 2002
V. M. Kisel, E. O. Kostyrko, M. O. Platonov, V. A. Kovtunenko
By condensation of 4-(2-bromomethyl)-3,4,5,6-tetrahydro-2H-pyran-4-carbonitrile with anthranilic acid, its derivatives substituted in the benzene ring (esters, nitrile), and with esters of 2-aminothiophene-3-carboxylic acids and 3-amino-5-bromobenzofuran-2-carboxylic acid there have been synthesized novel derivatives which include spiro-linked tetrahydropyran and 5,10-dihydro-3H-pyrimido[1,2-b]iso...... hiện toàn bộ
Pyrazines and their N-oxidesChemistry of Heterocyclic Compounds - Tập 4 - Trang 533-535 - 1971
A. S. Elina, I. S. Musatova, G. P. Syrova
Two isomeric mono-N-oxides of 2-aminopyrazine and the 1,4-di-N-oxide have been synthesized. A marked fall in the capacity of these compounds for nucleophilic exchange reactions and for rearrangements in acid and alkaline media has been found, which distinguishes them from the corresponding N-oxides of 2-aminoquinoxaline.
Syntheses of di- and tetrahydropyrrolesChemistry of Heterocyclic Compounds - Tập 4 - Trang 462-463 - 1971
V. M. Berezovskii, V. B. Spiro, L. Ya. Denisova, B. M. Sheiman
By the Michael's condensation of 3-methyl-1-nitro-1-butene with esters of α-acetoglutaric and acetosuccinic acids and of 2-methyl-1-nitropropene with acetylacetone we have synthesized the corresponding γ-nitrocarbonyl compounds, which have been converted by reductive cyclization into 3-ethoxycarbonyl-4-isopropyl-3-methoxycarbonylethyl-2-methyl-Δ1-pyrroline, 3-ethoxycarbonyl-3-ethoxycarbonylmethyl-...... hiện toàn bộ
Mass spectrometric study of 4-azafluorenesChemistry of Heterocyclic Compounds - Tập 14 - Trang 200-203 - 1978
V. P. Zvolinskii, P. I. Zakharov, V. K. Shevtsov, A. V. Varlamov, V. G. Pleshakov, G. A. Vasil'ev, N. S. Prostakov
The dissociative ionization of 4-azafluorene and its methyl and phenyl derivatives was investigated. The relative intensity of the [M — CH3]+ ion peak depends on the position of the CH3 group in the 4-azafluorene ring. It was established that the loss of an RCN particle (R=H, CH3, and C6H5) for unsubstituted 4-azafluorene takes place from the M+ and [M — H]+ ion, exclusively from the [M — H]+ ion ...... hiện toàn bộ
The reaction of ethylene sulfide with isothiocyanatesChemistry of Heterocyclic Compounds - Tập 3 - Trang 166-169 - 1967
V. S. Etlis, A. P. Sineokov, G. A. Razuvaev
Ethylene sulfide reacts with isothlocyanates in the presence of triethylamine catalyst at 20°C, to give low-molecular copolymerization products having the general formula [-C(NR)-S-CH2-CH2-S-]n. Their hydrolysis gives a salt of the amine and [-C(O)-S-CH2CH2S-]n. Vacuum-heating the latter gives ethylenedithiocarbonate, and hydrogen peroxide oxidation in formic acid gives ethane disulfonic acid. Tre...... hiện toàn bộ
Synthesis of methyl esters of 5-aroyl-6-aryl-2-oxo-1,2,3,6-tetra-hydropyrimidine-4-carboxylic acidsChemistry of Heterocyclic Compounds - - 2009
V. L. Gein, I. V. Krylova, E. P. Tsypliakova, A. R. Gaifullina, L. I. Varkentin, M. I. Vakhrin
Methyl esters of 5-aroyl-6-aryl-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acids were synthesized from three component mixtures of methyl esters of aroylpyruvic acids, urea, and substituted benzaldehydes. 8-Hydroxy-4,5-diphenyl-3,4-dihydropyrimido[4,5-d]pyridazin-2(1H)-one was synthesized by the reaction of 5-benzoyl-2-oxo-6-phenyl-1,2,3,6-tetrahydropyrimidin-4-carboxylate with hydrazine hydr...... hiện toàn bộ