STAT5 signaling in expression of the α-subunit of interleukin-2 receptor in human blood lymphocytesCell and Tissue Biology - Tập 7 - Trang 397-406 - 2013
E. V. Mityushova, A. N. Shatrova, V. V. Zenin, N. D. Aksenov, I. I. Marakhova
A comparative study of STAT3 and STAT5 activity (assessed by tyrosine
phosphorylation level) and the expression of an α-subunit of the interleukin-2
receptor (examined by cytophotometric evaluation of CD25 cell number) during
phytohemaglutinin (PHA)-induced proliferation of human blood lymphocytes (HBLs)
has been carried out. It was found that the level of STAT3 phosphorylation was
high both in re... hiện toàn bộ
Differences in functional activity of cultivated human vascular endothelium cells derived from various donorsCell and Tissue Biology - Tập 5 - Trang 353-357 - 2011
O. N. Shcheglovitova, N. N. Sklyankina, N. V. Boldyreva
The endothelia of blood vessels fulfill multiple functions in an organism under
physiological or pathological conditions. It is possible to model the processes
that take place in the vascular endothelium on cultivated endothelial cells.
Unlike permanent cell lines, research on primary cell cultures may lead to
inconsistent results. In this work, endothelium cultures derived from umbilical
cords of... hiện toàn bộ
The effect of the cell microenvironment on cell functions associated with tumor promotion and progressionCell and Tissue Biology - Tập 7 - Trang 329-334 - 2013
I. I. Koldin, E. M. Treshchalina, Yu. Yu. Sharovskaya, T. K. Dubovaya, V. A. Kobliakov
To study the role of the cellular microenvironment in tumor promotion and
progression, transformed cells of rat embryonic fibroblasts (CL-1 clone) were
transplanted into transgenic immunodeficient mice and cells of the formed tumor
were converted into culture (CL-1-1 cells). Cells before and after
transplantation were compared in morphology, growth rate, and permeability of
intercellular gap junct... hiện toàn bộ