Cancer Nanotechnology

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Biosynthesis of silver nanoparticles using the extract of Alternanthera sessilis—antiproliferative effect against prostate cancer cells
Cancer Nanotechnology - Tập 4 - Trang 137-143 - 2013
M. Jannathul Firdhouse, P. Lalitha
Green synthesis of silver nanoparticles was carried out using the aqueous extract of Alternanthera sessilis under various experimental conditions. The aqueous extract of Alternanthera sessilis showed significant potential for the quick reduction of silver ions. The synthesized silver nanoparticles were characterized with UV-visible absorption spectrophotometer, XRD, SEM, and FTIR analysis. The ave... hiện toàn bộ
Aluminum nanoparticles enhance anticancer immune response induced by tumor cell vaccine
Cancer Nanotechnology - - 2010
Zhao Sun, Wei Wang, Rui Wang, Jiaqi Duan, Yan Hu, Jing Ma, Jiayan Zhou, Sishen Xie, Xin Lu, Zhaohui Zhu, Shuchang Chen, Yuanli Zhao, Haiyan Xu, Chen Wang, Xiao Yang
Lipid polymeric nanoparticles modified with tight junction-modulating peptides promote afatinib delivery across a blood–brain barrier model
Cancer Nanotechnology - Tập 12 Số 1 - 2021
Yu Li Lo, Lin H, Shu Ting Hong, Cheng-Yen Chang, Chen Shen Wang, Anya Maan Yuh Lin
Abstract Background Brain metastases from non-small cell lung cancer (NSCLC) remain one of the most challenging malignancies. Afatinib (Afa) is an orally administered irreversible ErbB family blocker approved for epidermal growth factor receptor (EGFR)-mutated NSCLC. However, the incidence of brain metastases in patients with NSCLC and EGFR mutation is high. One of the major obstacles in the treat... hiện toàn bộ
Nanotechnology approaches to addressing HER2-positive breast cancer
Cancer Nanotechnology - Tập 11 - Trang 1-26 - 2020
Bryan E. White, Molly K. White, Het Adhvaryu, Issam Makhoul, Zeid A. Nima, Alexandru S. Biris, Nawab Ali
Breast cancer is a major cause of cancer-associated deaths in the United States. It was estimated that 12% of women in the U.S. will develop invasive breast cancer in their lifetime. The human epidermal growth factor receptor (HER2/neu) is a growth-promoting protein that is overexpressed in 15–20% of breast cancers (HER2-positive breast cancer). HER2-positive breast cancer generally grows and spre... hiện toàn bộ
Early stage evaluation of colon cancer using tungsten disulfide quantum dots and bacteriophage nano-biocomposite as an efficient electrochemical platform
Cancer Nanotechnology - Tập 13 Số 1 - 2022
Ramin Pourakbari, Mehdi Yousefi, Balal Khalilzadeh, Mahsa Haddad Irani-nezhad, Alireza Khataee, Leili Aghebati‐Maleki, Alireza Soleimanian, Amin Kamrani, Forough Chakari-Khiavi, Rozita Abolhasan, Morteza Motallebnezhad, Farhad Jadidi‐Niaragh, Bahman Yousefi, Hossein Samadi Kafil, Mohammad Hojjat‐Farsangi, Mohammad‐Reza Rashidi
AbstractBackgroundRecently, biosensors have become popular analytical tools for small analytes due to their high sensitivity and wide analytical range. In the present work, development of a novel biosensing method based on tungsten disulfide quantum dots (WS2QDs)-Au for rapidly and selectively detecting c-Met protein is introduced. As a proof of concept, M13 bacteriophage-based biosensors were use... hiện toàn bộ
Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
Cancer Nanotechnology - Tập 14 - Trang 1-21 - 2023
Camila Sales Nascimento, Naiara Clemente Tavares, Izabella Cristina Andrade Batista, Mônica Maria Magalhães Caetano, Eneida Santos de Oliveira, Stella Garcia Colombarolli, Anna Carolina Pinheiro Lage, Rodrigo Corrêa-Oliveira, Érica Alessandra Rocha Alves, Celso Pinto de Melo, Carlos Eduardo Calzavara-Silva
Breast cancer is the neoplastic disease with the highest incidence and mortality in the female population worldwide. Treatment remains challenging due to various factors. Therefore, it is of great importance to develop new therapeutic strategies that promote the safe destruction of neoplastic cells without compromising patients' quality of life. Among advances in the treatment of breast cancer, im... hiện toàn bộ
Investigating the anticancer and anti-angiogenic effects of graphene oxide nanoparticles containing 6-gingerol modified with chitosan and folate
Cancer Nanotechnology - Tập 14 - Trang 1-13 - 2023
Angham Hakim Abdulzahra Al-Janabi, Nasim Hayati Roodbari, Masoud Homayouni Tabrizi
The use of nanocarriers to improve the targeting of treatment plays a key role in the treatment of many diseases, including cancer. This study was carried out to synthesize graphene oxide (GO) containing 6-gingerol (Ging) modified with chitosan (CS)-folic acid (FA) nanoparticles (Ging-GO-CS-FA) to improve the anti-cancer effects of Ging. After the synthesis of nanoparticles, the average size, surf... hiện toàn bộ
Investigation of mitochondria-dependent apoptosis pathway and lipid peroxidation level induced by biosynthesized silver nanoparticles: caspase-3 activation, BAK1/BCLx regulation and malondialdehyde production
Cancer Nanotechnology - Tập 15 - Trang 1-16 - 2024
Haiwei Xiong, Xiaoyan Nie, Wei Cao, Jia Zhu, Jian Chen, Ruihao Liu, Yingliang Li
Nowadays, silver nanoparticles (AgNPs) have attracted the attention of many researchers due to their special physical, chemical, and biological properties. There is strong evidence that biogenic AgNPs can act as potent anticancer agents through the production of reactive oxygen species (ROS) and initiate the mitochondrial pathway of apoptosis. That is why we decided to use Nepeta bracteata Benth f... hiện toàn bộ
HepG2 exosomes coated luteolin nanoparticles remodeling hepatic stellate cells and combination with sorafenib for the treatment of hepatocellular carcinoma
Cancer Nanotechnology - - 2024
Shengjie Ye, Xier Pan, Linghui Zou, Shuting Ni, Lei Zhang, Yanlong Hong, Kaili Hu
Hepatocellular carcinoma (HCC) is a common malignant tumor with high mortality and recurrence rate. The efficacy of the first-line drug sorafenib is impeded by drug resistance, which is closely related to activated hepatic stellate cells (HSCs). The natural product luteolin is good at alleviating the activation of HSC. However, its clinical application is limited to poor solubility, bioavailabilit... hiện toàn bộ
Mô hình sinh học của hạt nano dựa trên gadolinium trong việc tăng cường độ nhạy bức xạ cho tia photon kilovoltage: một nghiên cứu Monte Carlo Dịch bởi AI
Cancer Nanotechnology - - 2023
Jianan Wu, Xiaohan Xu, Ying Liang, Tujia Chen, Enzhuo Quan, Luhua Wang
Các hạt nano dựa trên gadolinium (GdNP) được sử dụng lâm sàng để tăng cường độ nhạy bức xạ của tế bào khối u. Tuy nhiên, các nghiên cứu về cơ chế và mô hình sinh học của việc tăng cường bức xạ bằng GdNP vẫn còn sơ bộ. Nghiên cứu này nhằm điều tra cơ chế tăng cường bức xạ của GdNP đối với tia photon kilovoltage bằng cách sử dụng mô phỏng Monte Carlo (MC) và thiết lập mô hình sinh học dựa trên mô hì... hiện toàn bộ
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