Cancer Cell International
SCIE-ISI SCOPUS (2001-2025)
1475-2867
Cơ quản chủ quản: BMC , BioMed Central Ltd.
Lĩnh vực:
Cancer ResearchOncologyGenetics
Phân tích ảnh hưởng
Các bài báo tiêu biểu
The role of hypoxia in the tumor microenvironment and development of cancer stem cell: a novel approach to developing treatment
Tập 21 Số 1
AbstractHypoxia is a common feature of solid tumors, and develops because of the
rapid growth of the tumor that outstrips the oxygen supply, and impaired blood
flow due to the formation of abnormal blood vessels supplying the tumor. It has
been reported that tumor hypoxia can: activate angiogenesis, thereby enhancing
invasiveness and risk of metastasis; increase survival of tumor, as well as
suppr...
Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy
Tập 5 Số 1 - 2005
AbstractBortezomib is a highly selective, reversible inhibitor of the 26S
proteasome that is indicated for single-agent use in the treatment of patients
with multiple myeloma who have received at least 2 prior therapies and are
progressing on their most recent therapy. Clinical investigations have been
completed or are under way to evaluate the safety and efficacy of bortezomib
alone or in combina...
Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo
Tập 12 - Trang 1-8 - 2012
Cyclooxygenase-2(COX-2) promotes carcinogenesis, tumor proliferation,
angiogenesis, prevention of apoptosis, and immunosuppression. Meanwhile, COX-2
over-expression has been associated with tumor behavior and prognosis in several
cancers. This study investigated the antitumor effects of the selective COX-2
inhibitor, Celecoxib, on breast cancer in vitro and in vivo. Human breast cancer
MCF-7 and M...
Construction and comprehensive analysis of a ceRNA network to reveal potential prognostic biomarkers for hepatocellular carcinoma
Tập 19 Số 1 - 2019
Roles of sphingosine-1-phosphate signaling in cancer
- 2019
AbstractThe potent pleiotropic lipid mediator sphingosine-1-phosphate (S1P)
participates in numerous cellular processes, including angiogenesis and cell
survival, proliferation, and migration. It is formed by one of two sphingosine
kinases (SphKs), SphK1 and SphK2. These enzymes largely exert their various
biological and pathophysiological actions through one of five G protein-coupled
receptors (S...