Cancer Cell International

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Anticancer effects of bifidobacteria on colon cancer cell lines
Cancer Cell International - Tập 21 - Trang 1-12 - 2021
Zeinab Faghfoori, Mohammad Hasan Faghfoori, Amir Saber, Azimeh Izadi, Ahmad Yari Khosroushahi
Colorectal cancer (CRC), with a growing incidence trend worldwide, is resistant to apoptosis and has uncontrolled proliferation. It is recently reported that probiotic microorganisms exert anticancer effects. The genus Bifidobacterium, one of the dominant bacterial populations in the gastrointestinal tract, has received increasing attention because of widespread interest in using it as health-prom... hiện toàn bộ
Retraction Note to: Degradation of long non-coding RNA-CIR decelerates proliferation, invasion and migration, but promotes apoptosis of osteosarcoma cells
Cancer Cell International - - 2022
Shiwei Liu, Jingchao Li, Liang Kang, Yueyang Tian, Yuan Xue
The role of peptide and DNA vaccines in myeloid leukemia immunotherapy
Cancer Cell International - Tập 13 Số 1 - Trang 1-7 - 2013
Lin, Chen, Li, Yangqiu
While chemotherapy and targeted therapy are successful in inducing the remission of myeloid leukemia as acute myeloid leukemia (AML) and chronic myeloid leukemia (CML), the disease remains largely incurable. This observation is likely due to the drug resistance of leukemic cells, which are responsible for disease relapse. Myeloid leukemia vaccines may most likely be beneficial for eradicating mini... hiện toàn bộ
Systems biology based meth-miRNA–mRNA regulatory network identifies metabolic imbalance and hyperactive cell cycle signaling involved in hepatocellular carcinoma onset and progression
Cancer Cell International - Tập 19 - Trang 1-16 - 2019
Kashif Rafiq Zahid, Mingyang Su, Abdur Rehman Raza Khan, Shiming Han, Gou Deming, Umar Raza
Hepatocellular carcinoma (HCC) is one of the leading cause of cancer associated deaths worldwide. Independent studies have proposed altered DNA methylation pattern and aberrant microRNA (miRNA) levels leading to abnormal expression of different genes as important regulators of disease onset and progression in HCC. Here, using systems biology approaches, we aimed to integrate methylation, miRNA pro... hiện toàn bộ
Single nucleotide polymorphisms of CD20 gene and their relationship with clinical efficacy of R-CHOP in patients with diffuse large B cell lymphoma
Cancer Cell International - Tập 13 Số 1 - Trang 1-7 - 2013
Ding, Huirong, Jin, Xuan, Ding, Ning, Fu, Zhiying, Song, Yuqin, Zhu, Jun
R-CHOP has significantly improved survival rates of patients with diffuse large B cell lymphoma (DLBCL) by ~20% as compared to CHOP. CD20 antigen, highly expressed on more than 80% of B-cell lymphomas, is the target for rituximab. The goal of our study was to examine polymorphism in the CD20 gene in Chinese DLBCL population and whether CD20 gene polymorphism is associated with clinical response to... hiện toàn bộ
PESV represses non-small cell lung cancer cell malignancy through circ_0016760 under hypoxia
Cancer Cell International - - 2021
Hong Zhang, Haojian Zhang, Jinmin Zhu, Huan Liu, Qin Zhou
Abstract Background Non-small cell lung cancer (NSCLC) accounts for more than 80% of lung cancers, which is the most common malignant tumor worldwide. Polypeptide extract from scorpion venom (PESV) has been reported to inhibit NSCLC process. The present study aims to reveal the roles of PESV in NSCLC progression under hypoxia and the inner mechanism. Methods The expression levels of circular RNA 0... hiện toàn bộ
Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines
Cancer Cell International - Tập 6 - Trang 1-12 - 2006
Ivan Depasquale, Denys N Wheatley
Lovastatin and other statins may reduce the development of melanomas. The effects on melanoma cells and their ability to enhance angiogenesis in a co-culture system presented an opportunity to assess whether Lovastatin act on melanoma cells, HUVEC or both types of cells. Direct effects of co-culturing two different malignant melanoma cells (A375 and G361) on the process of angiogenesis in vitro wa... hiện toàn bộ
Small nucleolar RNAs signature (SNORS) identified clinical outcome and prognosis of bladder cancer (BLCA)
Cancer Cell International - - 2020
Rui Cao, Bo Ma, Lushun Yuan, Gang Wang, Ye Tian
Abstract Background Small nucleolar RNAs (snoRNAs) are a new non-coding RNAs (ncRNAs), which have not been widely investigated and are identified to be involved in tumorigenesis. But the function of snoRNAs in BLCA has not been reported yet. Methods SnoRNAs signature (SNORS) was constructed through LASSO cox regression analysis. Integrated analysis of candidate snoRNAs was performed to detect the ... hiện toàn bộ
PRC2 mediated KLF2 down regulation: a therapeutic and diagnostic axis during tumor progression
Cancer Cell International - Tập 23 - Trang 1-12 - 2023
Negin Taghehchian, Amirhosein Maharati, Iman Akhlaghipour, Amir Sadra Zangouei, Meysam Moghbeli
Surgery and chemo-radiotherapy are used as the common first-line treatment options in many cancers. However, tumor relapse is observed in many cancer patients following such first-line treatments. Therefore, targeted therapy according to the molecular cancer biology can be very important in reducing tumor recurrence. In this regard, a wide range of monoclonal antibodies against the growth factors ... hiện toàn bộ
High CFP score indicates poor prognosis and chemoradiotherapy response in LARC patients
Cancer Cell International - Tập 21 - Trang 1-11 - 2021
Siyi Lu, Zhenzhen Liu, Bingyan Wang, Fei Li, Yan Meng, Junwei Wang, Yuxia Wang, Hao Wang, Xin Zhou, Wei Fu
Preoperative tumor markers, inflammation, and nutritional status are considered important predictors of prognosis and tumor response in locally advanced rectal cancer (LARC) patients. This study aims to explore the prognostic and predictive role of carcinoembryonic antigen (CEA), the Fibrinogen-Albumin Ratio Index (FARI), the Prognostic Nutritional Index (PNI) in LARC patients and compared them wi... hiện toàn bộ
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