Cancer Cell International
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Anticancer effects of bifidobacteria on colon cancer cell lines
Cancer Cell International - Tập 21 - Trang 1-12 - 2021
Colorectal cancer (CRC), with a growing incidence trend worldwide, is resistant to apoptosis and has uncontrolled proliferation. It is recently reported that probiotic microorganisms exert anticancer effects. The genus Bifidobacterium, one of the dominant bacterial populations in the gastrointestinal tract, has received increasing attention because of widespread interest in using it as health-prom......
Single nucleotide polymorphisms of CD20 gene and their relationship with clinical efficacy of R-CHOP in patients with diffuse large B cell lymphoma
Cancer Cell International - Tập 13 Số 1 - Trang 1-7 - 2013
R-CHOP has significantly improved survival rates of patients with diffuse large B cell lymphoma (DLBCL) by ~20% as compared to CHOP. CD20 antigen, highly expressed on more than 80% of B-cell lymphomas, is the target for rituximab. The goal of our study was to examine polymorphism in the CD20 gene in Chinese DLBCL population and whether CD20 gene polymorphism is associated with clinical response to......
PESV represses non-small cell lung cancer cell malignancy through circ_0016760 under hypoxiaAbstract
Background
Non-small cell lung cancer (NSCLC) accounts for more than 80% of lung cancers, which is the most common malignant tumor worldwide. Polypeptide extract from scorpion venom (PESV) has been reported to inhibit NSCLC process. The present study aims to reveal the roles of PESV in NSCL... ...
Cancer Cell International - - 2021
Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines
Cancer Cell International - Tập 6 - Trang 1-12 - 2006
Lovastatin and other statins may reduce the development of melanomas. The effects on melanoma cells and their ability to enhance angiogenesis in a co-culture system presented an opportunity to assess whether Lovastatin act on melanoma cells, HUVEC or both types of cells. Direct effects of co-culturing two different malignant melanoma cells (A375 and G361) on the process of angiogenesis in vitro wa......
High CFP score indicates poor prognosis and chemoradiotherapy response in LARC patients
Cancer Cell International - Tập 21 - Trang 1-11 - 2021
Preoperative tumor markers, inflammation, and nutritional status are considered important predictors of prognosis and tumor response in locally advanced rectal cancer (LARC) patients. This study aims to explore the prognostic and predictive role of carcinoembryonic antigen (CEA), the Fibrinogen-Albumin Ratio Index (FARI), the Prognostic Nutritional Index (PNI) in LARC patients and compared them wi......
Sự biểu hiện quá mức của lncRNA HOXA11-AS thúc đẩy quá trình chuyển đổi biểu mô - mesenchymal bằng cách ức chế miR-200b trong ung thư phổi không tế bào nhỏ Dịch bởi AI
Cancer Cell International - Tập 17 - Trang 1-11 - 2017
Các nghiên cứu gần đây đã xác nhận rằng các RNA không mã hóa dài (lncRNAs) liên quan đến nhiều chức năng sinh học và đóng vai trò quan trọng trong sự tiến triển của ung thư ở người, nghiên cứu này nhằm mục đích phát hiện mối liên hệ giữa RNA không mã hóa dài HOXA11-AS và quá trình chuyển đổi biểu mô - mesenchymal (EMT) trong ung thư phổi không tế bào nhỏ (NSCLC). Mức độ biểu hiện của lncRNA HOXA11......
Monoclonal antibodies and chimeric antigen receptor (CAR) T cells in the treatment of colorectal cancerAbstract Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer deaths worldwide. Besides common therapeutic approaches, such as surgery, chemotherapy, and radiotherapy, novel therapeutic approaches, including immunotherapy, have been an advent in CRC treatment. The immunotherapy approaches try to elicit patients` immune respo... ...
Cancer Cell International -
The miR-199a-3p regulates the radioresistance of esophageal cancer cells via targeting the AK4 gene
Cancer Cell International - Tập 18 - Trang 1-11 - 2018
MiRNAs was recognized as vital regulators involved in cancer development. Radioresistance remains a major obstacle for effective treatment of cancers. The mechanisms on the miRNA-mediated radioresistance of cancers are still poorly understood. The main subject of this study is to find new miRNA biomarker that regulates the radioresistance of esophageal cancer (EC). The cumulative dose of radiation......
The role of bile acids in cellular invasiveness of gastric cancer
Cancer Cell International - Tập 18 - Trang 1-8 - 2018
Bile acids have been implicated in the development of digestive tract malignancy by epidemiological, clinical and animal studies. The growth and transformation signaling by most of the bile acids is thought to be related to the induced cyclooxygenase-2 (COX-2) expression and increased production of prostaglandin E2 (PGE2). The highly hydrophobic bile acids such as chenodeoxycholic acid (CD) and de......
Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer risk
Cancer Cell International - Tập 21 - Trang 1-7 - 2021
Endometrial cancer is one of the most common female reproductive system tumors. Ninjurin2 (NINJ2) is a new adhesion factor. As a vascular susceptibility gene, it is highly expressed in other cancers and promotes the growth of cancer cells. We conducted an association analysis between NINJ2 gene polymorphism and endometrial cancer risk. Five SNPs rs118050317, rs75750647, rs7307242, rs10849390 and r......
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