Multimodal Evoked Potential Studies in Leukodystrophies of ChildrenCanadian Journal of Neurological Sciences - Tập 15 Số 1 - Trang 26-31 - 1988
Linda J. De Meirleir, Margot J. Taylor, William J. Logan
ABSTRACT:Evoked potentials were studied in 22 children with leukodystrophy [10 metachromatic leukodystrophy (MLD), 4 Pelizaeus-Merzbacher (PM), 3 Krabbes, 2 adrenoleukodystrophy (ALD), and one each of Alexander's, Canavan's and multiple sulphatase deficiency (MSD) diseases]. The ABRs were abnormal in all patients (except for the younger ALD), but varied with the ty...... hiện toàn bộ
Stigma of EpilepsyCanadian Journal of Neurological Sciences - Tập 35 Số 4 - Trang 436-440 - 2008
Nancy F. Bandstra, Carol Camfield, Peter Camfield
Epilepsy directly affects 50 million people worldwide.Most can achieve excellent seizure control; however, people living with epilepsy continue to suffer from enacted or perceived stigma that is based on myths, misconceptions and misunderstandings that have persisted for thousands of years. This paper reviews the frequency and nature of stigma toward epilepsy. Significant negative attitude...... hiện toàn bộ
The Frequency of Phospholipid Antibodies in an Unselected Stroke PopulationCanadian Journal of Neurological Sciences - Tập 25 Số 1 - Trang 64-69 - 1998
L Metz, Steven M. Edworthy, R. Mydlarski, Fritzler Mj
ABSTRACT:Background:Antibodies to cardiolipin and other phospholipids have been associated with recurrent thrombotic events, including stroke.Methods:Over a 16 month period we assessed an unselected cohort of 151 ...... hiện toàn bộ
Development of Criteria for Epilepsy Genetic Testing in Ontario, CanadaCanadian Journal of Neurological Sciences - Tập 46 Số 1 - Trang 7-13 - 2019
Puneet Jain, Danielle M. Andrade, Elizabeth Donner, David A. Dyment, Asuri N. Prasad, Sharan Goobie, Kym M. Boycott, Matthew A. Lines, O. Carter Snead
AbstractMultiple genes/variants have been implicated in various epileptic conditions. However, there is little general guidance available on the circumstances in which genetic testing is indicated and test selection in order to guide optimal test appropriateness and benefit. This is an account of the development of guidelines for genetic testing in epilepsy, which ...... hiện toàn bộ
Peripheral Neurophathies Associated With Chronic Renal FailureCanadian Journal of Neurological Sciences - Tập 7 Số 2 - Trang 89-96 - 1980
C. F. Bolton
SUMMARY:A variety of peripheral nerve disorders may be associated with chronic renal failure. The polyneuropathy due to uremic toxins is a distal, motor and sensory polyneuropathy in which there is segmental demyelination, axonal degeneration, and segmental remyelination. The nature of the uremic toxin and the underlying mechanism of these changes is unknown.... hiện toàn bộ
Cerebral Hemodynamics in MigraineCanadian Journal of Neurological Sciences - Tập 4 Số 4 - Trang 245-249 - 1977
Vladimir Hachinski, Jes Olesen, John W. Norris, B. Larsen, E. Enevoldsen, N. A. Lassen
SUMMARY:Clinical and angiographic findings in migraine are briefly reviewed in relation to cerebral hemodynamic changes shown by regional cerebral blood flow (rCBF) studies. Three cases of migraine studied by the intracarotid xenon 133 method during attacks are reported.In classic migraine, with typical prodromal symptoms, a decrease in cerebral bl...... hiện toàn bộ
Acute Hyperglycemia and In-Hospital Mortality in Spontaneous Intracerebral HemorrhageCanadian Journal of Neurological Sciences - Tập 50 Số 1 - Trang 115-118 - 2023
Himanshu Gupta, Simon Beshara, Aristeidis H. Katsanos, Tushar Patil, Saeed Alzahrani, Jerry Yeou-Wei Chen, Abdulrahman Alharbi, Nasim Zamir, Kelvin Ng, Carlos S. Kase, Ashkan Shoamanesh
ABSTRACT:Hyperglycemia is reported to predict worse outcome in patients with stroke, including intracerebral hemorrhage (ICH). In 83 consecutive cases of ICH at a tertiary stroke center, hyperglycemia (serum glucose >7 mmol/L) compared to normoglycemia at presentation was associated with higher rates of in-hospital mortality (51.2% vs. 26.2%, OR 2.3, CI 1.2–7.6,...... hiện toàn bộ
The Design of the Canadian UnRuptured Endovascular versus Surgery (CURES) TrialCanadian Journal of Neurological Sciences - Tập 38 Số 2 - Trang 236-241 - 2011
Tim E. Darsaut, J. Max Findlay, Jean Raymond
Background:Once a decision has been made to treat an intact aneurysm, the best treatment remains uncertain. Both surgical and endovascular management strategies are commonly performed for these lesions. Surgical clipping, for years the standard treatment, is gradually becoming supplanted by endovascular treatment. However, ther...... hiện toàn bộ
Does the Engram of Kindling Model the Engram of Normal Long Term Memory?Canadian Journal of Neurological Sciences - Tập 2 Số 4 - Trang 385-394 - 1975
Graham V. Goddard, Robert M. Douglas
SUMMARY:The kindling effect is a relatively permanent alteration in brain function which results from repeated electrical or chemical stimulation and culminates in the appearance of electrographic and behavioral convulsions whenever the original stimulus is reapplied. The effect results from tetanic activation in the anterior cortex, limbic system or associated are...... hiện toàn bộ