The Impact of Fatigue on Patients with Multiple Sclerosis Tập 21 Số 1 - Trang 9-14 - 1994
John D. Fisk, Amanda Pontefract, Paul G. Ritvo, Catherine J. Archibald, T. Jock Murray
ABSTRACT:Although fatigue is recognized as a symptom of MS, there have been insufficient methods for evaluating this symptom. We administered the Fatigue Impact Scale to 85 MS patients and 20 hypertensive patients. Neurologic impairment, mental health, and general health status were also assessed. MS patients reported significantly higher fatigue impact than hypert...... hiện toàn bộ 3-Nitropropionic Acid - Exogenous Animal Neurotoxin and Possible Human Striatal Toxin Tập 18 Số 4 - Trang 492-498 - 1991
Albert C. Ludolph, Libin Chen, Peter S. Spencer, John P. Hammerstad, Mohammad I. Sabri
ABSTRACT:3-Nitropropionic acid (3-NPA) — a suicide inhibitor of succinate dehydrogenase — is a widely distributed plant and fungal neurotoxin known to induce damage to basal ganglia, hippocampus, spinal tracts and peripheral nerves in animals. Recent reports from Northern China indicate that 3-NPA is also likely to be responsible for the development of putaminal ne...... hiện toàn bộ Hemispherectomy for Seizures Revisited Tập 10 Số 2 - Trang 71-78 - 1983
T Rasmussen
SUMMARY:The serious, late complication of superficial cerebral hemosiderosis, which appears after several years in 1/4–1/3 of patients who have undergone hemispherectomy, has resulted in recent years in a considerable reluctance to carry out this operation despite the fact it has proved to be highly effective in patients with medically refractory seizures associate...... hiện toàn bộ Does the Engram of Kindling Model the Engram of Normal Long Term Memory? Tập 2 Số 4 - Trang 385-394 - 1975
Graham V. Goddard, Robert M. Douglas
SUMMARY:The kindling effect is a relatively permanent alteration in brain function which results from repeated electrical or chemical stimulation and culminates in the appearance of electrographic and behavioral convulsions whenever the original stimulus is reapplied. The effect results from tetanic activation in the anterior cortex, limbic system or associated are...... hiện toàn bộ Cortical Excitability in Amyotrophic Lateral Sclerosis: A Clue to Pathogenesis Tập 20 Số 1 - Trang 11-16 - 1993
Andrew Eisen, Bhanu Pant, Heather Stewart
ABSTRACT:Motor evoked potentials (MEPs) were recorded from selected non-wasted, non-denervated hand muscles in 40 patients with Amyotrophic Lateral Sclerosis (ALS) with both upper and lower motor neuron signs. In most the compound muscle action potential (CMAP) of the target muscle was normal. Compared to the control group, cortical threshold in ALS varied consider...... hiện toàn bộ The Increased Susceptibility of Women to Multiple Sclerosis Tập 19 Số 4 - Trang 466-471 - 1992
Pierre Duquette, J Pleines, Marc Girard, Louise Charest, Micheline Senécal‐Quevillon, Caroline Masse
ABSTRACT:Many diseases with an auto-immune etiology have a skewed sex distribution. In the majority of instances, women are affected more frequently than men. A review of population studies demonstrates that the preponderance of women in multiple sclerosis (MS) is almost constant. We show that this preponderance is further increased in early as well as in late-onse...... hiện toàn bộ Stigma of Epilepsy Tập 35 Số 4 - Trang 436-440 - 2008
Nancy F. Bandstra, Carol Camfield, Peter Camfield
Epilepsy directly affects 50 million people worldwide.Most can achieve excellent seizure control; however, people living with epilepsy continue to suffer from enacted or perceived stigma that is based on myths, misconceptions and misunderstandings that have persisted for thousands of years. This paper reviews the frequency and nature of stigma toward epilepsy. Significant negative attitude...... hiện toàn bộ