British Journal of Psychiatry
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The Dexamethasone Suppression Test and Prediction of Outcome in Patients Receiving ECTTwenty-six in-patients satisfying DSM-III criteria for major depressive episode were assessed using the Newcastle Diagnostic and ECT Predictor Scales and the dexamethasone suppression test (DST), prior to commencing a course of electroconvulsive therapy (ECT). The Newcastle ECT Predictor Scale was successful in predicting both immediate outcome and outcome over the 6 months following ECT; ... ...
British Journal of Psychiatry - Tập 150 Số 3 - Trang 315-318 - 1987
The Present Status of Electroconvulsive Therapy
British Journal of Psychiatry - Tập 139 Số 4 - Trang 265-283 - 1981
Depression as a Consequence of Inadequate Neurochemical Adaptation in Response to StressorsStressors induce behavioural disturbances and neurochemical changes in animals, some of which are reminiscent of the symptoms and presumed neurochemical concomitants of depression in humans. Just as in humans, where considerable inter-individual variability is evident in the symptom profile of depression, there is marked inter-individual and inter-strain variability in the behavioural effe... ...
British Journal of Psychiatry - Tập 160 Số S15 - Trang 36-43 - 1992
Depressive disorders in Europe: prevalence figures from the ODIN studyBackground This is the first report on the epidemiology of depressive disorders from the European Outcome of Depression International Network (ODIN) study. Aims To assess the prevalence of depressive disorders in randomly selected samples of the general population in five European countries....
British Journal of Psychiatry - Tập 179 Số 4 - Trang 308-316 - 2001
Placebo run-in period in studies of depressive disordersBackground In spite of the virtually ubiquitous nature of the initial 10-day placebo run-in period (IPR) in drug trials, there is little empirical data establishing its relevance. Method Data from 593 subjects were examined retrospectively to determine whether or not the prognosis of subjects min...
British Journal of Psychiatry - Tập 173 Số 3 - Trang 242-248 - 1998
Antidepressant medicationsv.cognitive therapy in people with depression with or without personality disorderBackground There is conflicting evidence about comorbid personality pathology in depression treatments. Aims To test the effects of antidepressant drugs and cognitive therapy in people with depression distinguished by the presence or absence of personality disorder. <... ...
British Journal of Psychiatry - Tập 192 Số 2 - Trang 124-129 - 2008
Somatoform disorders in general practiceBackground General practitioners play a pivotal part in the recognition and treatment of psychiatric disorders. Identifying somatoform disorders is important for the choice of treatment. Aims To quantify the prevalence of, and functional impairment associated with, somatoform disorders, and their...
British Journal of Psychiatry - Tập 184 Số 6 - Trang 470-476 - 2004
Schizophrenia and suicide: Systematic review of risk factorsBackground Suicide risk is greatly increased in schizophrenia. Detection of those at risk is clinically important. Aims To identify risk factors for suicide in schizophrenia. Method The international literature on case-control and cohor...
British Journal of Psychiatry - Tập 187 Số 1 - Trang 9-20 - 2005
High-potency cannabis and the risk of psychosisBackground People who use cannabis have an increased risk of psychosis an effect attributed to the active ingredient δ9-tetrahydrocannabinol (Δ9-THC). There has recently been concern over an increase in the concentration of Δ9-THC in the cannabis available in many countries. Aims To investigate w...
British Journal of Psychiatry - Tập 195 Số 6 - Trang 488-491 - 2009
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