Panic Symptoms after Inhalation of Carbondioxide

British Journal of Psychiatry - Tập 144 Số 5 - Trang 503-507 - 1984
Marcel A. van den Hout1, Eric Griez2
1Department of Medical Psychology, State University of Limburg, P.O. Box 616, 6200 MD Maastricht, Netherlands
2Department of Clinical Psychiatry, State University of Limburg

Tóm tắt

SummaryThe effects of inhaling a mixture of 35 per cent carbon dioxide and 65 per cent oxygen on the occurrence of panic symptoms defined by the DSM III, was investigated. Compared to a placebo (air), carbon dioxide produced more panic symptoms. If carbon dioxide inhalation was preceded by intake of a beta-blocker (60 mg propranolol), less symptoms occurred than if preceded by a placebo. The results are compared with earlier reports on the effects of lactate infusion. It is argued that panic disorders can be conceptualized as a fear of internal (panic) sensations and that inhalation of a mixture of carbon dioxide and oxygen may constitute an effective exposure treatment.

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