Bone and Joint Research
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MRI of articular cartilage at microscopic resolutionThis review briefly summarises some of the definitive studies of articular cartilage by microscopic MRI (µMRI) that were conducted with the highest spatial resolutions. The article has four major sections. The first section introduces the cartilage tissue, MRI and µMRI, and the concept of image contrast in MRI. The second section describes the characteristic profiles of three relaxation ti... ... hiện toàn bộ
Bone and Joint Research - Tập 2 Số 1 - Trang 9-17 - 2013
The use of rats and mice as animal models inex vivobone growth and development studiesIn vivo animal experimentation has been one of the cornerstones of biological and biomedical research, particularly in the field of clinical medicine and pharmaceuticals. The conventional in vivo model system is invariably associated with high production costs and strict ethical considerations. These limitations led to the evolution of an ex vivo model system which partially or completely ... ... hiện toàn bộ
Bone and Joint Research - Tập 5 Số 12 - Trang 610-618 - 2016
Patient-reported outcome measures after total knee arthroplastyObjectives A lack of connection between surgeons and patients in evaluating the outcome of total knee arthroplasty (TKA) has led to the search for the ideal patient-reported outcome measure (PROM) to evaluate these procedures. We hypothesised that the desired psychometric properties of the ideal outcome tool have not been uniformly addressed in studies de... ... hiện toàn bộ
Bone and Joint Research - Tập 4 Số 7 - Trang 120-127 - 2015
Enhancement of fracture healing in the rat, modulated by compounds that stimulate inducible nitric oxide synthaseObjectives We investigated the effects on fracture healing of two up-regulators of inducible nitric oxide synthase (iNOS) in a rat model of an open femoral osteotomy: tadalafil, a phosphodiesterase inhibitor, and the recently reported nutraceutical, COMB-4 (consisting of L-citrulline, Paullinia cupana, ginger and muira puama), given orally for either 14 or... ... hiện toàn bộ
Bone and Joint Research - Tập 6 Số 2 - Trang 90-97 - 2017
Altered expression of microRNA during fracture healing in diabetic ratsObjectives Diabetes mellitus (DM) is known to impair fracture healing. Increasing evidence suggests that some microRNA (miRNA) is involved in the pathophysiology of diabetes and its complications. We hypothesized that the functions of miRNA and changes to their patterns of expression may be implicated in the pathogenesis of impaired fracture healing in DM.... ... hiện toàn bộ
Bone and Joint Research - Tập 7 Số 2 - Trang 139-147 - 2018
Outcomes following fractured neck of femur in an Australian metropolitan teaching hospitalObjectives To determine the morbidity and mortality outcomes of patients presenting with a fractured neck of femur in an Australian context. Peri-operative variables related to unfavourable outcomes were identified to allow planning of intervention strategies for improving peri-operative care. Methods ... ... hiện toàn bộ
Bone and Joint Research - Tập 2 Số 8 - Trang 162-168 - 2013
Age-related differences in the neck strength of adolescent rugby playersObjectives To evaluate the neck strength of school-aged rugby players, and to define the relationship with proxy physical measures with a view to predicting neck strength. Methods Cross-sectional cohort study involving 382 rugby playing schoolchildren at three Scottish schools (all male, aged ... ... hiện toàn bộ
Bone and Joint Research - Tập 1 Số 7 - Trang 152-157 - 2012
Tổng số: 7
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