Biotherapy
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* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Effects of interleukin-2 (IL-2) on human plasma lipid, lipoprotein, and C-reactive protein
Biotherapy - Tập 2 - Trang 193-198 - 1990
Six patients with confirmed malignant disease received four consecutive weekly cycles of human recombinant interleukin-2 (IL-2) 4 days/week, continuous iv. infusion, 3 × 106 U/m2/day. Plasma cholesterol decreased a mean of 7% within 24 hours after IL-2 infusion and decreased by 33% within 4 days. Plasma cholesterol was significantly lower than baseline concentration by day 21 (−21%), and day 25 (−......
An attempt to inhibit the course of amyotrophic lateral sclerosis (ALS) by suppressor factor
Biotherapy - - 1996
High levels of soluble IFN γ receptor α chain in the plasma of rheumatoid arthritis patients
Biotherapy - Tập 11 - Trang 53-57 - 1998
Soluble receptors for hormones and cytokines have beendescribed. They can serve as natural blockers of theirrespective ligands. The natural soluble interferongamma receptor (sIFNγR) has been isolated andcharacterized only in urine. Chromatography of human(hu) plasma from rheumatoid arthritis (RA) patientsand controls on immobilized hu IFN γ orantibodies against IFN γ R α chainpermitted us to isola......
Early and late hormonal modulation of cholinergic maturation in culture of embryonic mesencephali
Biotherapy - Tập 5 - Trang 205-214 - 1992
Dissociated cells from 13- and 17-day-old embryonic rat mesencephali have grown in primary cultures in order to compare the early and late influences of different agents - insulin, dexamethasone and nerve growth factor (NGF) - on the expression of cholinergic maturation process. We have studied cholin acetyltransferase (ChAT) activity, which is regarded as a specific marker for cholinergic functio......
A case report of a 9-year old boy with polyarteritis nodosa in which a combination therapy of corticosteroids and a photosensitive dye Platonin was effective
Biotherapy - Tập 3 - Trang 261-264 - 1991
Polyarteritis nodosa (PN), characterized by vasculitis of medium and small sized arteries, is uncommon in children. This disease is thought to be concerned with some abnormal immune responses. Platonin (4,4′-dimethyl-3,3′-di-n-heptyl-8-[2-(4-methyl-3-n-heptylthiazole)]-2,2′-dicar bocyanine diiodine) is one of the photosensitive dyes of trithiazole pentamethine cyanine. It has been reported that pl......
Interleukin-3
Biotherapy - Tập 2 - Trang 337-345 - 1990
Interleukin-3 (IL-3) is a hemopoietic growth factor involved in the survival, proliferation and differentiation of multipotent hemopoietic cells. In five mammalian species, including man, the gene encoding IL-3 has been isolated and expressed to yield the mature recombinant proteins. The human IL-3 gene encodes a protein of 133 amino acids with two conserved cysteine residues and 2 potential N-lin......
Preliminary results in HIV-1-infected patients treated with transfer factor (TF) and Zidovudine (ZDV)
Biotherapy - Tập 9 - Trang 49-54 - 1996
The efficiency of HIV-1 specific transfer factor (TF) administration, combined with Zidovudine (ZDV), in asymptomatic persistent generalised lymphadenopaty, or AIDS related complex (ARC) patients was evaluated. Twenty patients were randomly assigned to receive only ZDV (1st group) or ZDV together with HIV-1-specific TF (2nd group). HIV-1-specific TF was administered orally at 2 × 107 cell equivale......
Inhibition of tumor cell growth by a human B-cell line
Biotherapy - Tập 8 - Trang 1-6 - 1994
An Adenocarcinoma cell line (Breast-M) and an Epstein-Barr virus (EBV)-infected B-cell line (Hairy-BM) were established from breast tumor tissue. The Hairy-BM was CD20+, CD25 (Tac)+ and surface immunoglobulin (sIg)+. Hairy-BM suppressed the in vitro proliferation of Breast-M in a time and a dose-dependent manner. The suppression was also found in 5 different human tumor targets showing tumor-Hairy......
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