Biotechnology Journal
SCIE-ISI SCOPUS (2006-2023)
1860-7314
1860-6768
Đức
Cơ quản chủ quản: WILEY-V C H VERLAG GMBH , Wiley-VCH Verlag
Lĩnh vực:
Medicine (miscellaneous)Molecular MedicineApplied Microbiology and Biotechnology
Các bài báo tiêu biểu
Biobutanol: An attractive biofuelAbstract Biofuels are an attractive means to prevent a further increase of carbon dioxide emissions. Currently, gasoline is blended with ethanol at various percentages. However, butanol has several advantages over ethanol, such as higher energy content, lower water absorption, better blending ability, and use in conventional combustion engines without modification. ... ...
Tập 2 Số 12 - Trang 1525-1534 - 2007
PEGylation of therapeutic proteinsAbstract Since the first PEGylated product was approved by the Food and Drug Administration in 1990, PEGylation has been widely used as a post‐production modification methodology for improving biomedical efficacy and physicochemical properties of therapeutic proteins. Applicability and safety of this technology have been proven by use of various PEGylated pharmaceut... ...
Tập 5 Số 1 - Trang 113-128 - 2010
Advanced biofuel production in microbesAbstract The cost‐effective production of biofuels from renewable materials will begin to address energy security and climate change concerns. Ethanol, naturally produced by microorganisms, is currently the major biofuel in the transportation sector. However, its low energy content and incompatibility with existing fuel distribution and storage infrastructure limits... ...
Tập 5 Số 2 - Trang 147-162 - 2010
Microfluidics Based Point‐of‐Care DiagnosticsPoint‐of‐care (POC) diagnostic devices have been predicted to provide a boon in health care especially in the diagnosis and detection of diseases. POC devices have been found to have many advantages like a rapid and precise response, portability, low cost, and non‐requirement of specialized equipment. The major objective of a POC diagnostic research is to develop a c...
Tập 13 Số 1 - 2018
Manufacturing of recombinant therapeutic proteins in microbial systemsAbstract Recombinant therapeutic proteins have gained enormous importance for clinical applications. The first recombinant products have been produced in E. coli more than 20 years ago. Although with the advent of antibody‐based therapeutics mammalian expression systems have experienced a major boost, microbial expression systems continue to be widely used in indust... ...
Tập 1 Số 2 - Trang 164-186 - 2006
Metagenomics: Concept, methodology, ecological inference and recent advancesAbstract Microorganisms constitute two third of the Earth's biological diversity. As many as 99% of the microorganisms present in certain environments cannot be cultured by standard techniques. Culture‐independent methods are required to understand the genetic diversity, population structure and ecological roles of the majority of organisms. Metagenomics is the geno... ...
Tập 4 Số 4 - Trang 480-494 - 2009
Camelina as a sustainable oilseed crop: Contributions of plant breeding and genetic engineeringAbstract Camelina is an underutilized Brassicaceae oilseed plant with a considerable agronomic potential for biofuel and vegetable oil production in temperate regions. In contrast to most Brassicaceae, camelina is resistant to alternaria black spot and other diseases and pests. Sequencing of the camelina genome revealed an undifferentiated allohexaploid genome with ... ...
Tập 10 Số 4 - Trang 525-535 - 2015
Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactorsAbstract Production of human mesenchymal stem cells for allogeneic cell therapies requires scalable, cost‐effective manufacturing processes. Microcarriers enable the culture of anchorage‐dependent cells in stirred‐tank bioreactors. However, no robust, transferable methodology for microcarrier selection exists, with studies providing little or no reason explaining wh... ...
Tập 11 Số 4 - Trang 473-486 - 2016
Towards automated production and drug sensitivity testing using scaffold‐free spherical tumor microtissuesAbstract Although the relevance of three‐dimensional (3‐D) culture has been recognized for years and exploited at an academic level, its translation to industrial applications has been slow. The development of reliable high‐throughput technologies is clearly a prerequisite for the industrial implementation of 3‐D models. In this study the robustness of spherical mic... ...
Tập 6 Số 12 - Trang 1488-1496 - 2011
Towards dynamic metabolic flux analysis in CHO cell culturesAbstract Chinese hamster ovary (CHO) cells are the most widely used mammalian cell line for biopharmaceutical production, with a total global market approaching $100 billion per year. In the pharmaceutical industry CHO cells are grown in fed‐batch culture, where cellular metabolism is characterized by high glucose and glutamine uptake rates combined with high rates ... ...
Tập 7 Số 1 - Trang 61-74 - 2012