Biophysics

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Apoptotic nature of erythrocyte hemolysis induced by low doses of ionizing radiation
Biophysics - Tập 60 - Trang 79-84 - 2015
V. N. Krylov, A. V. Deriugina, S. N. Pleskova, V. A. Kalinin
It is shown that exposure of rat erythrocytes to low doses of ionizing radiation (0.04, 0.08, 0.16, 0.25, and 0.33 mGy) leads to nonlinear changes in lipid peroxidation processes in the membrane of erythrocytes, their electrophoretic mobility, and osmotic resistance. Ionizing radiation in the dose range from 0.08 to 0.16 mGy apparently triggers apoptosis, leading to deceleration of hemolysis and s...... hiện toàn bộ
Mutual disposition of short conformationally stanch oligopeptides in the 3D structure of globular proteins
Biophysics - Tập 54 - Trang 748-752 - 2010
A. V. Batyanovskii, N. G. Esipova, S. E. Shnoll
The disposition of conformationally stanch, helix-prone tetrapeptides and of longer segments containing them in proteins of different structural and functional groups (PDBselect and CATH samples) has been analyzed. Quasirandom Monte Carlo experiments show that the disposition of such segments can be regarded as stochastic. At that, ∼60% of stanch peptides in the protein globules have at least one ...... hiện toàn bộ
Can local energy minimization refine the PDB structures of different resolution universally?
Biophysics - - 2009
M. G. Godsie, A. P. Gromova, I. V. Oferkin, P. V. Mironov
Local energy minimization was statistically tested as the refinement strategy for PDB structure pairs of different resolution. The 13 pairs of structures with the only difference being the resolution were extracted from PDB and represented structures of 11 identical proteins obtained with different x-ray diffraction techniques. The rmsd distribution was calculated for these pairs before and after ...... hiện toàn bộ
The Effect of an Electrochemically Activated Water Solution on Plant Polysaccharides: Phenomenology and Spectrometry
Biophysics - - 2024
A. G. Pogorelov, L. G. Ipatova, A. I. Panait, M. A. Pogorelova, A. A. Gulin, V. N. Pogorelova
Changes in the properties of polysaccharides in an electrochemically activated aqueous solution have been studied using UV-Vis spectrometry, time-of-flight secondary ion mass spectrometry and scanning electron microscopy. It is shown that the studied solutions of polysaccharides of plant origin (agar, soluble starch, and food starch) are subject to modification, the direction of which is determine...... hiện toàn bộ
Hydrogen peroxide in artificial photosynthesizing systems
Biophysics - Tập 59 - Trang 169-182 - 2014
A. V. Lobanov, G. G. Komissarov
From the point of view of the concepts of hydrogen peroxide as a source of photosynthetic oxygen (hydrogen) coordination and photochemical properties of chlorophyll and its aggregates towards hydrogen peroxide were considered. The binding energy of H2O and H2O2 with chlorophyll and chlorophyllide depending on their form (monomers, dimers and trimers) was estimated by quantum chemical calculations....... hiện toàn bộ
Long-period endogenous oscillations in fish population size: Mathematical modeling
Biophysics - Tập 58 - Trang 245-257 - 2013
A. E. Bobyrev, V. A. Burmensky, E. A. Kriksunov, A. B. Medvinsky, N. I. Nurieva, A. V. Rusakov
We present a mathematical model of an aquatic community, where the size-and-age structure of hydrobiont populations is taken into account and the corresponding trophic interactions between zooplankton, peaceful fish, and predatory fish are described. We show that interactions between separate components of the aquatic community can give rise to long-period oscillations in fish population size. The...... hiện toàn bộ
Properties of hybridization isotherms upon binding of ligands on microchips
Biophysics - Tập 54 - Trang 581-583 - 2010
M. V. Golovkin, O. V. Matveeva, Yu. D. Nechipurenko
A simple thermodynamic model describing microarray oligo-target hybridization has been constructed. The relationship between the hybridization signal intensity and Gibbs free energy for oligo-target duplex formation has been considered. The behavior of this function, which we called energy hybridization isotherm, in response to target concentration change was modeled at different ratios of oligo/t...... hiện toàn bộ
Oxygen effect in heat-induced DNA damage
Biophysics - Tập 52 - Trang 185-190 - 2007
A. V. Chernikov, S. V. Gudkov, I. N. Shtarkman, V. I. Bruskov
The major kinds of heat-induced damage to DNA (depurination, guanine oxidation to 8-oxoguanine, cytosine deamination to uracil) were shown to depend in their extent on the oxygen content in solution. Formation of hydrogen peroxide in water upon heating was enhanced in the presence of D2O and decreased by various scavengers of singlet oxygen, corroborating the involvement of 1O2 in the thermal gene...... hiện toàn bộ
Searching for Sequencing Signal Anomalies Associated with Genomic Structural Variations
Biophysics - - 2024
I. V. Bezdvornykh, N. A. Cherkasov, A. A. Kanapin, A. A. Samsonova
Genomic structural variations (SVs) are among the main sources of genetic diversity. Structural variants as mutagens may significantly affect human health, causing hereditary diseases and cancers. Existing methods analyze high-throughput sequencing data to find structural variants. Despite substantial progress in their development, the methods still fail to detect structural variations with an acc...... hiện toàn bộ
Electrostatic Interaction of Globins with Phospholipid Membranes
Biophysics - Tập 65 - Trang 913-919 - 2021
G. B. Postnikova, E. A. Shekhovtsova, V. S. Sivozhelezov
For the structures of sperm whale myoglobin (swMb), horse heart myoglobin (hhMb), hemoglobin I (HbI) from botfly Gasterophilus intestinalis (giHbI), and monomeric and dimeric hemoglobins HbI and HbII from Lucina pectinata mollusk (lpHbI and lpHbII), roles of electrostatic interactions in stabilization of native conformations of the heme cavity were analyzed, as well as their possible destabilizat...... hiện toàn bộ
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