Biochemistry (Moscow)

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Polyphosphates as an energy source for growth of Saccharomyces cerevisiae
Biochemistry (Moscow) - Tập 79 - Trang 478-482 - 2014
L. V. Trilisenko, T. V. Kulakovskaya
Cells of the yeast Saccharomyces cerevisiae with a low content of polyphosphates (polyP) are characterized by disturbance of growth in medium with 0.5% glucose. The parent strain with polyP level reduced by phosphate starvation had a longer lag phase. The growth rate of strains with genetically determined low content of polyP due to their enhanced hydrolysis (CRN/pMB1_PPN1 Sc is a superproducer of...... hiện toàn bộ
Biological effects of 3,5-diiodothyronine (T2)
Biochemistry (Moscow) - Tập 70 Số 2 - Trang 164-172 - 2005
Fernando Goglia
Klotho protein: Its role in aging and central nervous system pathology
Biochemistry (Moscow) - - 2017
I. S. Boksha, T. A. Prokhorova, O. K. Savushkina, E. B. Tereshkina
This review is devoted to Klotho protein and recent evidences for its functions in the brain. Information on transcriptional regulation of the klotho gene and posttranslational modifications of the protein resulting in multiple forms of Klotho is reviewed. Evidence is summarized that Klotho regulates the activity of protein factors, enzymes, and receptors, including data suggesting the importance ...... hiện toàn bộ
Phosphorylation regulates interaction of 210-kDa myosin light chain kinase N-terminal domain with actin cytoskeleton
Biochemistry (Moscow) - Tập 80 - Trang 1288-1297 - 2015
E. L. Vilitkevich, A. Y. Khapchaev, D. S. Kudryashov, A. V. Nikashin, J. P. Schavocky, T. J. Lukas, D. M. Watterson, V. P. Shirinsky
High molecular weight myosin light chain kinase (MLCK210) is a multifunctional protein involved in myosin II activation and integration of cytoskeletal components in cells. MLCK210 possesses actin-binding regions both in the central part of the molecule and in its N-terminal tail domain. In HeLa cells, mitotic protein kinase Aurora B was suggested to phosphorylate MLCK210 N-terminal tail at serine...... hiện toàn bộ
Recombinant Human Cyclophilin A in Combination with Adoptive T-cell Therapy Improves the Efficacy of Cancer Immunotherapy in Experimental Models in vivo
Biochemistry (Moscow) - Tập 88 - Trang 590-599 - 2023
Anastasiia A. Kalinina, Dmitry B. Kazansky, Ludmila M. Khromykh
Adoptive T-cell therapy (ACT) is successfully applied in cancer treatment; however, its efficiency can be limited by a low viability, short persistence time, and loss of functional activity of T-cells after adoptive transfer. The search for novel immunomodulators that can improve the viability, expansion, and functions of T-cells after their infusion with the minimal side effects could contribute ...... hiện toàn bộ
Effect of Polysaccharides and Human Plasma Lipoproteins on the Secretion of Cystatin C by Peritoneal Macrophages from Normal and Tumor Bearing Mice
Biochemistry (Moscow) - Tập 69 - Trang 295-298 - 2004
O. N. Poteryaeva, L. M. Polyakov, T. A. Korolenko, T. V. Zueva, G. S. Russkikh, L. E. Panin
Intact peritoneal macrophages in vitro secreted the cysteine proteinase inhibitor cystatin C. Polysaccharides stimulated cystatin C secretion: lipopolysaccharide < carboxymethylated β-D-glucan < sulfoethylated β-D-glucan. Human plasma low-density- (LDL) and high-density lipoproteins (HDL) are still more potent inducers of cystatin C secretion by macrophages. Peritoneal macrophages from mice with e...... hiện toàn bộ
HuR stabilizes lnc-Sox5 mRNA to promote tongue carcinogenesis
Biochemistry (Moscow) - Tập 82 - Trang 438-445 - 2017
Lifang Wang, Shucheng Ye, Junye Wang, Zhenfang Gu, Yanhui Zhang, Chunmei Zhang, Xuezhen Ma
Long noncoding RNAs (lncRNAs) have been recently regarded as systemic regulators in multiple biological processes including tumorigenesis. In this study, we report an ultra-highly expressed lncRNA, lnc-Sox5, in tongue tumor tissues. The results imply that lnc-Sox5 may play vital role in tongue carcinoma progression. We observed that the growth of Tca8113 cells was suppressed by lnc-Sox5 downregula...... hiện toàn bộ
Measuring the pH dependence of hydrogenase activities
Biochemistry (Moscow) - Tập 72 Số 9 - Trang 968-973 - 2007
Anatoly A. Tsygankov, E. A. Minakov, Н. А. Зорин, K. S. Gosteva, Oleg G. Voronin, Arkady A. Karyakin
Macrophage/foam cell is an attribute of inflammation: Mechanisms of formation and functional role
Biochemistry (Moscow) - Tập 77 - Trang 327-338 - 2012
M. I. Dushkin
Transformation of macrophages into foam cells is traditionally considered in the context of atherogenesis, because lipid accumulation is believed to be a consequence of uptake of oxidized low density lipoproteins (oxLDL) through scavenger receptors (SR) of macrophages. However, an excessive uptake of oxLDL is recently shown to trigger compensatory mechanisms of cholesterol elimination from macroph...... hiện toàn bộ
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