Biochemistry (Moscow)
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Increased Extracellular Sodium Concentration as a Factor Regulating Gene Expression in Endothelium
Biochemistry (Moscow) - Tập 87 - Trang 489-499 - 2022
Hyperosmotic stimulation of endothelial cells often leads to its dysfunction accompanied, among other things, by proinflammatory response. The mechanisms of this phenomenon are not fully understood. It may arise due to increase in the plasma Na+ concentration, due to increase in the extracellular osmolarity, increase in the intracellular Na+i/K+i ratio, and/or change in the cell stiffness. In the ...... hiện toàn bộ
Thermodynamics of the P-type Ferryl Form of Bovine Cytochrome c Oxidase
Biochemistry (Moscow) - Tập 86 - Trang 74-83 - 2021
Several ferryl states of the catalytic heme a3-CuB center of the respiratory cytochrome c oxidases (CcOs) are observed during the reduction of O2 to H2O. One of the P-type ferryl forms, PM, is produced by the reaction of the two-electron reduced CcO with O2. In this state, the heme a3 iron is in the ferryl state and a free radical should be also present at the catalytic center. However, the energe...... hiện toàn bộ
Unique Bipolar Gene Architecture in the RNA Genome of Influenza A Virus
Biochemistry (Moscow) - Tập 85 Số 3 - Trang 387-392 - 2020
Na+-Translocating Ferredoxin:NAD+ Oxidoreductase Is a Component of Photosynthetic Electron Transport Chain in Green Sulfur Bacteria
Biochemistry (Moscow) - Tập 84 - Trang 1403-1410 - 2019
Genomes of photoautotrophic organisms containing type I photosynthetic reaction center were searched for the rnf genes encoding Na+-translocating ferredoxin:NAD+ oxidoreductase (RNF). These genes were absent in heliobacteria, cyanobacteria, algae, and plants; however, genomes of many green sulfur bacteria (especially marine ones) were found to contain the full rnf operon. Analysis of RNA isolated ...... hiện toàn bộ
Signal Transduction in Neutrophil Chemotaxis
Biochemistry (Moscow) - Tập 66 - Trang 351-368 - 2001
This review discusses current knowledge on signal transduction pathways controlling chemotaxis of neutrophils and similar cells. Most neutrophil chemoattractants bind to seven-transmembrane-helix receptors. These receptors activate trimeric G proteins of the Gi class in neutrophils to initiate chemotaxis. Phospholipases Cβ, phosphoinositide 3-kinase γ, and PH domain-containing proteins play variou...... hiện toàn bộ
Modern Methods for Assessment of microRNAs
Biochemistry (Moscow) - Tập 87 - Trang 425-442 - 2022
The review discusses modern methods for the quantitative and semi-quantitative analysis of miRNAs, which are small non-coding RNAs affecting numerous biological processes such as development, differentiation, metabolism, and immune response. miRNAs are considered as promising biomarkers in the diagnosis of various diseases.
Catalytic and Signaling Role of Peroxiredoxins in Carcinogenesis
Biochemistry (Moscow) - Tập 84 - Trang 79-100 - 2019
Cancer cells experience strong oxidative stress caused by disorders in cell metabolism and action of external factors. For survival, cancer cells have developed a highly efficient system of antioxidant defense, some of the most important elements of which are peroxiredoxins (Prxs). Prxs are an evolutionarily ancient family of selenium-independent peroxidases that reduce a wide range of organic and...... hiện toàn bộ
Biosynthesis of uridine diphosphate N-acetyl-L-fucosamine in a cell-free system from Salmonella arizonae O:59
Biochemistry (Moscow) - - 2005
The conversion of uridine diphosphate N-acetyl-D-glucosamine into uridine diphosphate N-acetyl-L-fucosamine was demonstrated with enzymes from cytoplasmic fraction of Salmonella arizonae O:59 cells in the presence of NAD+ (NADP+) and NADPH. The reaction product was identified by ion-pair, reverse-phase HPLC with the use of synthetic nucleoside diphosphate sugar standards under conditions specially...... hiện toàn bộ
Studies of the Process of Amyloid Formation by Aβ Peptide
Biochemistry (Moscow) - Tập 83 Số S1 - Trang S62-S80 - 2018
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