Biochemical Society Transactions

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Latest developments in MUC1 immunotherapy
Biochemical Society Transactions - Tập 46 Số 3 - Trang 659-668 - 2018
Joyce Taylor‐Papadimitriou, Joy Burchell, Rosalind Graham, Richard Beatson
Currently, there is renewed interest in attempting to recruit the host immune system to eliminate cancers, and within this renewed activity, MUC1 continues to arouse interest. MUC1 has been considered a possible therapeutic target for the past 30 years as it is up-regulated, aberrantly glycosylated and its polarization is lost in many adenocarcinomas. Moreover, MUC1 is expressed by some haematopoi... hiện toàn bộ
Pathological implications of nitric oxide, superoxide and peroxynitrite formation
Biochemical Society Transactions - Tập 21 Số 2 - Trang 330-334 - 1993
Joseph S. Beckman, John P. Crow
Antioxidant therapy in children affected by irradiation from the Chernobyl nuclear accident
Biochemical Society Transactions - Tập 21 Số 3 - Trang 314S-314S - 1993
Ludmila G. Korkina, Igor B AFANAS'EF, Anthony T. Diplock
Glyoxalase I inhibitors in cancer chemotherapy
Biochemical Society Transactions - Tập 31 Số 6 - Trang 1378-1382 - 2003
Donald J. Creighton, Zhe-Bin Zheng, Ronald J. Holewinski, Diana S. Hamilton, Julie L. Eiseman
Several recent developments suggest that the GSH-dependent glyoxalase enzyme system deserves renewed interest as a potential target for antitumour drug development. This summary focuses on the design and development of new classes of tumoricidal agents that specifically target this elementary detoxification pathway in order to induce elevated concentrations of cytotoxic methylglyoxal in tumour cel... hiện toàn bộ
Regulation of pineal serotonin N-acetyltransferase activity
Biochemical Society Transactions - Tập 20 Số 2 - Trang 299-304 - 1992
David C. Klein, Nicolas L. Schaad, M. A. A. Namboordiri, Yu Li, Joan L. Weller
Systems biology markup language: Level 2 and beyond
Biochemical Society Transactions - Tập 31 Số 6 - Trang 1472-1473 - 2003
Andrew Finney, Michael Hucka
The SBML (systems biology markup language) is a standard exchange format for computational models of biochemical networks. We continue developing SBML collaboratively with the modelling community to meet their evolving needs. The recently introduced SBML Level 2 includes several enhancements to the original Level 1, and features under development for SBML Level 3 include model composition, multist... hiện toàn bộ
Tau protein in Alzheimer's disease
Biochemical Society Transactions - Tập 23 Số 1 - Trang 80-86 - 1995
Michel Goedert, Ross Jakes, Maria Grazia Spillantini, R. Anthony Crowther, Phillip Cohen, Eugeen Vanmechelen, A. Probst, Jürgen Götz, Kurt Bürki
Hippocampal nicotinic autoreceptors modulate acetylcholine release
Biochemical Society Transactions - Tập 21 Số 2 - Trang 429-431 - 1993
G. Wilkie, Peter H. Hutson, M.F.C. Stephens, Paul Whiting, Susan Wonnacott
Structural and conformational analysis of immunoglobulin-derived N-linked oligosaccharides
Biochemical Society Transactions - Tập 11 Số 2 - Trang 132-134 - 1983
Thomas W. Rademacher, Steven W. Homans, Daryl L. Fernandes, Raymond A. Dwek, Tsuguo Mizuochi, Tohru Taniguchi, Akira Kobata
A new method for measuring antioxidant activity
Biochemical Society Transactions - Tập 21 Số 2 - Trang 95S-95S - 1993
Nicholas J. Miller, Catherine Rice‐Evans, Michael J. Davies
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