Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine Tập 4 - Trang 1-12 - 2014
Shih-Yi Lin, Wu-Huei Hsu, Cheng-Chieh Lin, Chao-Jung Chen
Mass spectrometry (MS) is currently the most promising tool for studying
proteomics to investigate largescale proteins in a specific proteome. Emerging
MS-based proteomics is widely applied to decipher complex proteome for
discovering potential biomarkers. Given its growing usage in clinical medicine
for biomarker discovery to predict, diagnose and confer prognosis, MS-based
proteomics can benefit... hiện toàn bộ
Personalized medicine in Type 2 Diabetes Tập 4 - Trang 1-8 - 2014
Wen-Ling Liao, Fuu-Jen Tsai
Type 2 diabetes (T2D) is a global public health concern, its prevalence in Asia,
especially Taiwan, rising every year. The risk of developing T2D and diabetes
complications is not only controlled by environmental but also by genetic
factors. Genetic association studies have shown polymorphisms at specific loci
may help identify individuals at greatest risk and response to oral antidiabetic
drugs. ... hiện toàn bộ
Alleviative effects from boswellic acid on acetaminophen-induced hepatic injury Tập 6 - Trang 1-8 - 2016
Lung-Che Chen, Li-Hong Hu, Mei-Chin Yin
Protective effects of boswellic acid (BA) against acetaminophen (APAP)-induced
hepatotoxicity in Balb/ cA mice were examined. BA, at 0.05 or 0.1%, was supplied
for 4 weeks. Acute liver injury was induced by APAP treatment. Results showed
that BA intake increased hepatic BA bioavailability. APAP treatment decreased
glutathione (GSH) level, increased reactive oxygen species (ROS) and oxidized
glutat... hiện toàn bộ
The contributions of the tissue inhibitor of metalloproteinase-1 genotypes to triple negative breast cancer risk Tập 6 - Trang 1-6 - 2016
Wen-Shin Chang, Liang-Chih Liu, Chieh-Lun Hsiao, Chen-Hsien Su, Hwei-Chung Wang, Hong-Xue Ji, Chia-Wen Tsai, Ming-Chei Maa, Da-Tian Bau
The tissue inhibitors of metalloproteinases (TIMPs) are a family of
multifunctional proteins which have been shown to be upregulated in various
types of cancers. However, the contribution of TIMPs in breast cancer is not
fully understood, not to mention triple negative breast cancer (TNBC). This
study’s aim was to evaluate the contribution of TIMP-1 rs4898, rs6609533, and
rs2070584 genotypes to th... hiện toàn bộ
Wound dressings – a review Tập 5 - Trang 1-5 - 2015
Selvaraj Dhivya, Viswanadha Vijaya Padma, Elango Santhini
Wound healing is a dynamic and complex process which requires suitable
environment to promote healing process. With the advancement in technology, more
than 3000 products have been developed to treat different types of wounds by
targeting various aspects of healing process. The present review traces the
history of dressings from its earliest inception to the current status and also
discusses the a... hiện toàn bộ
Quercetin suppresses cellular migration and invasion in human head and neck squamous cell carcinoma (HNSCC) Tập 6 - Trang 1-6 - 2016
Chien-Yi Chan, Chia-Hsien Lien, Ming-Fen Lee, Chun-Yin Huang
Head and neck squamous cell carcinoma (HNSCC) with aberrant epidermal growth
factor receptor (EGFR) signaling is often associated with a poor prognosis and a
low survival rate. Hence, efficient inhibition of the EGFR signaling-mediated
malignancy would improve survival rate. In a previous study, we demonstrated
that quercetin appears to be a potent anti-tumorigenic agent through its
inhibition of ... hiện toàn bộ