Tissue distribution of naringenin conjugated metabolites following repeated dosing of naringin to rats Tập 4 - Trang 1-6 - 2014
Shiuan-Pey Lin, Yu-Chi Hou, Shang-Yuan Tsai, Meng-Ju Wang, Pei-Dawn Lee Chao
Background: Naringin is a major antioxidant in Citrus fruits and herbs. To
clarify molecular forms distributed to various tissues, we investigated tissue
distribution of naringin and relevant metabolites in rats after repeated dosing.
Methods: Male Sprague-Dawley rats were orally administered naringin (210 mg/kg)
twice daily for eight days. At 6 h post the 17th dose, various tissues including
live... hiện toàn bộ
Quercetin suppresses cellular migration and invasion in human head and neck squamous cell carcinoma (HNSCC) Tập 6 - Trang 1-6 - 2016
Chien-Yi Chan, Chia-Hsien Lien, Ming-Fen Lee, Chun-Yin Huang
Head and neck squamous cell carcinoma (HNSCC) with aberrant epidermal growth
factor receptor (EGFR) signaling is often associated with a poor prognosis and a
low survival rate. Hence, efficient inhibition of the EGFR signaling-mediated
malignancy would improve survival rate. In a previous study, we demonstrated
that quercetin appears to be a potent anti-tumorigenic agent through its
inhibition of ... hiện toàn bộ
Vascular Endothelial Growth Factor -460 C/T BstUI Gene Polymorphism is associated with Primary Open Angle Glaucoma Tập 4 - Trang 1-4 - 2014
Hui-Ju Lin, Wen-Lu Chen, Ter-Hsin Chen, Yung-Jen Kung, Lei Wan
Hypoxia and nitric oxide (NO) play important roles in the onset and progression
of glaucoma. Vascular endothelial growth factor (VEGF) is one of the main
factors responsive to hypoxia and NO. In this study, we investigated the
association between the BstUI C/T VEGF gene polymorphism and primary open angle
glaucoma (POAG). 60 POAG patients and 78 healthy volunteers were enrolled in
this study. The ... hiện toàn bộ
The contributions of the tissue inhibitor of metalloproteinase-1 genotypes to triple negative breast cancer risk Tập 6 - Trang 1-6 - 2016
Wen-Shin Chang, Liang-Chih Liu, Chieh-Lun Hsiao, Chen-Hsien Su, Hwei-Chung Wang, Hong-Xue Ji, Chia-Wen Tsai, Ming-Chei Maa, Da-Tian Bau
The tissue inhibitors of metalloproteinases (TIMPs) are a family of
multifunctional proteins which have been shown to be upregulated in various
types of cancers. However, the contribution of TIMPs in breast cancer is not
fully understood, not to mention triple negative breast cancer (TNBC). This
study’s aim was to evaluate the contribution of TIMP-1 rs4898, rs6609533, and
rs2070584 genotypes to th... hiện toàn bộ
Wound dressings – a review Tập 5 - Trang 1-5 - 2015
Selvaraj Dhivya, Viswanadha Vijaya Padma, Elango Santhini
Wound healing is a dynamic and complex process which requires suitable
environment to promote healing process. With the advancement in technology, more
than 3000 products have been developed to treat different types of wounds by
targeting various aspects of healing process. The present review traces the
history of dressings from its earliest inception to the current status and also
discusses the a... hiện toàn bộ