BioMedicine

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Down-regulation of voltage-gated Ca2+ channels in Ca2+ store-depleted rat insulinoma RINm5F cells
BioMedicine - Tập 3 - Trang 130-139 - 2013
Yuk M. Leung, Kar L. Wong, Shiao W. Chen, Dah Y. Lu, Chang S. Kuo, Yun R. Chen, Ya W. Chen, Tzu H. Cheng
Sambucus williamsii induced embryonic stem cells differentiated into neurons
BioMedicine - Tập 5 - Trang 1-5 - 2015
Shih-Ping Liu, Chien-Yu Hsu, Ru-Huei Fu, Yu-Chuen Huang, Shih-Yin Chen, Shinn-Zong Lin, Woei-Cherng Shyu
The pluripotent stem cells, including embryonic stem cells (ESCs), are capable of self-renewal and differentiation into any cell type, thus making them the focus of many clinical application studies. However, the efficiency of ESCs differentiated into neurons needs to improve. In this study, we tried to increase efficiently to a neural fate in the presence of various transitional Chinese medicines...... hiện toàn bộ
Personalized medicine in Type 2 Diabetes
BioMedicine - Tập 4 - Trang 1-8 - 2014
Wen-Ling Liao, Fuu-Jen Tsai
Type 2 diabetes (T2D) is a global public health concern, its prevalence in Asia, especially Taiwan, rising every year. The risk of developing T2D and diabetes complications is not only controlled by environmental but also by genetic factors. Genetic association studies have shown polymorphisms at specific loci may help identify individuals at greatest risk and response to oral antidiabetic drugs. ...... hiện toàn bộ
Activation of Toll-like receptors induces macrophage migration via the iNOS/Src/FAK pathway
BioMedicine - Tập 1 - Trang 11-15 - 2011
Ming-Chei Maa, Tzeng-Horng Leu
PPARα modulates gene expression profiles of mitochondrial energy metabolism in oral tumorigenesis
BioMedicine - Tập 6 - Trang 1-6 - 2016
Yi-Ping Huang, Nai Wen Chang
Metabolic reprogramming plays a crucial role in the development of cancer. The aim of this study was to explore the effect of fenofibrate, an agonist of peroxisome proliferator-activated receptor alpha (PPARα), on gene expression profiles of mitochondrial energy metabolism. Our results showed that PPARα expression was negatively correlated with tumor progression in an oral cancer mouse model. Acti...... hiện toàn bộ
Herpes zoster correlates with pyogenic liver abscesses in Taiwan
BioMedicine - Tập 6 - Trang 1-6 - 2016
Shen Mei-Ling, Liao Kuan-Fu, Tsai Sung-Mao, Lin MS Cheng-Li, Lai Shih-Wei
The purpose of the paper was to explore the relationship between herpes zoster and pyogenic liver abscesses in Taiwan. This was a nationwide cohort study. Using the database of the Taiwan National Health Insurance Program, there were 33049 subjects aged 20-84 years who were newly diagnosed with herpes zoster from 1998 to 2010 that were selected for our study, and they were our herpes zoster group....... hiện toàn bộ
Correlation of serum leptin and resistin levels with the metabolic risk factors of pre- and postmenopausal women in South India
BioMedicine - Tập 3 - Trang 167-173 - 2013
Tanu Priya, Minakshi G. Chowdhury, Karunamoorthy Vasanth, Thangavel Mahalingam Vijayakumar, Kaliappan Ilango, Aruna Agrawal, Govind Prasad Dubey
Vascular Endothelial Growth Factor -460 C/T BstUI Gene Polymorphism is associated with Primary Open Angle Glaucoma
BioMedicine - Tập 4 - Trang 1-4 - 2014
Hui-Ju Lin, Wen-Lu Chen, Ter-Hsin Chen, Yung-Jen Kung, Lei Wan
Hypoxia and nitric oxide (NO) play important roles in the onset and progression of glaucoma. Vascular endothelial growth factor (VEGF) is one of the main factors responsive to hypoxia and NO. In this study, we investigated the association between the BstUI C/T VEGF gene polymorphism and primary open angle glaucoma (POAG). 60 POAG patients and 78 healthy volunteers were enrolled in this study. The ...... hiện toàn bộ
Nutrition, psychoneuroimmunology and depression: the therapeutic implications of omega-3 fatty acids in interferon-α-induced depression
BioMedicine - Tập 5 - Trang 1-7 - 2015
Kuan-Pin Su
The unmet need of current pharmacotherapy and the high occurrence of somatic symptoms and physical illness in depression imply that the ‘monoamine hypothesis’ is insufficient in approaching the aetiology of depression. Clinically, depressed patients manifest higher levels of inflammatory biomarkers, while proinflammatory cytokines induce neuropsychiatric symptoms (sickness behaviour) as well as ma...... hiện toàn bộ
Metabolic Abnormality and Sleep Disturbance are Associated with Clinical Severity of Patients with Schizophrenia
BioMedicine - Tập 4 - Trang 1-5 - 2014
Chung-Chieh Hung, Chin-Chih Liao, Po-Lun Wu, Shin-Da Lee, Hsien-Yuan Lane
Schizophrenic patients suffer from more metabolic or sleep problems. Little is known about risk factors. We recruited 17 patients with chronic schizophrenia from the rehabilitation center in a medical center in Taiwan and measured their demographic data, cognitive performance, and physical fitness, metabolic profiles and sleep parameters. They were divided into two groups according to clinical sev...... hiện toàn bộ
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