Andrew J. Dorner, Samuel J. Goldman, James C. Keith
Interleukin-11 (IL-11) is a cytokine which interacts with a variety of
haemopoietic and non-haemopoietic cell types. Recombinant human IL-11 (rhIL-11;
oprelvekin) is produced in Escherichia coli and differs from the naturally
occurring protein only in the absence of the amino-terminal proline residue. In
synergy with other factors, rhIL-11 stimulates the growth of myeloid, erythroid,
and megakaryo... hiện toàn bộ
Basiliximab (Simulect®) is a recombinant chimeric murine/human IgG1 monoclonal
anti-interleukin-2 receptor antibody that is indicated for the prevention of
acute organ rejection in adult and pediatric renal transplant recipients in
combination with other immunosuppressive agents. Induction therapy with two
doses (day 0 and day 4) of intravenous basiliximab as part of double- or
triple-immunotherap... hiện toàn bộ