Behavioral and Brain Functions
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Gene × environment interactions for ADHD: synergistic effect of 5HTTLPR genotype and youth appraisals of inter-parental conflict
Behavioral and Brain Functions - Tập 6 - Trang 1-15 - 2010
Serotonin genes have been hypothesized to play a role in the etiology of
attention-deficit hyperactivity disorder (ADHD); prior work suggests that
serotonin may interact with psychosocial stressors in ADHD, perhaps via
mechanisms involved in emotional dysregulation. Because the development of
behavioral and emotional regulation depends heavily both on the child's
experience within the family conte...
Anticipation of difficult tasks: neural correlates of negative emotions and emotion regulation
Behavioral and Brain Functions - Tập 15 - Trang 1-13 - 2019
Difficult cognitive tasks are often associated with negative feelings. This can
be already the case for the mere anticipation of having to do a difficult task.
For the case of difficult math tasks, it was recently suggested that such a
negative emotional response may be exclusive to highly math-anxious individuals.
However, it is also conceivable that negative emotional responses simply reflect
th...
Functional Val66Met polymorphism of Brain-derived neurotrophic factor in type 2 diabetes with depression in Han Chinese subjects
Behavioral and Brain Functions - Tập 9 - Trang 1-8 - 2013
Brain-derived neurotrophic factor (BDNF) has been implicated in the pathogenesis
of major depression. Individuals with type 2 diabetes (T2DM) have a high
prevalence of major depression and low levels of BDNF. We therefore explored
whether the BDNF Val66Met polymorphism is associated with co-morbid depression
and whether depression affects the serum levels of BDNF in a Han Chinese
subjects with T2D...
Pharmacotherapy response and regional cerebral blood flow characteristics in patients with obsessive-compulsive disorder
Behavioral and Brain Functions - Tập 9 - Trang 1-8 - 2013
To analyze the correlation between the pharmacotherapy response and the
characteristics of the pre-treatment regional cerebral blood flow (rCBF) in
patients with obsessive-compulsive disorder (OCD). Single-photon
emission-computed tomography (SPECT) was used to determine the pre-treatment
rCBF in 30 OCD patients and 30 normal controls. Based on their clinical
remission response, the subjects were ...
Midazolam, hippocampal function, and transitive inference: Reply to Greene
Behavioral and Brain Functions - Tập 4 - Trang 1-5 - 2008
The transitive inference (TI) task assesses the ability to generalize learned
knowledge to new contexts, and is thought to depend on the hippocampus (Dusek &
Eichenbaum, 1997). Animals or humans learn in separate trials to choose stimulus
A over B, B over C, C over D and D over E, via reinforcement feedback.
Transitive responding based on the hierarchical structure A > B > C > D > E is
then tested...
Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism - effects of medication
Behavioral and Brain Functions - Tập 6 - Trang 1-14 - 2010
Children with attention-deficit/hyperactivity disorder (ADHD) show a marked
temporal variability in their display of symptoms and neuropsychological
performance. This could be explained in terms of an impaired glial supply of
energy to support neuronal activity. We pursued one test of the idea with
measures of a neurotrophin reflecting glial integrity (S100B) and the influences
of 8 cytokines on t...
Effect of intermittent exposure to ethanol and MDMA during adolescence on learning and memory in adult mice
Behavioral and Brain Functions - Tập 8 - Trang 1-12 - 2012
Heavy binge drinking is increasingly frequent among adolescents, and consumption
of 3,4-methylenedioxymethamphetamine (MDMA) is often combined with ethanol
(EtOH). The long-lasting effects of intermittent exposure to EtOH and MDMA
during adolescence on learning and memory were evaluated in adult mice using the
Hebb-Williams maze. Adolescent OF1 mice were exposed to EtOH (1.25 g/kg) on two
consecut...
Naringin provides neuroprotection in CCL2-induced cognition impairment by attenuating neuronal apoptosis in the hippocampus
Behavioral and Brain Functions - Tập 16 - Trang 1-13 - 2020
Chemokine C–C motif ligand 2 (CCL2) is one of the most widely recognised
proinflammatory chemokines in cognitive disorders. Currently, CCL2-targeting
drugs are extremely limited. Thus, this study aimed to explore the
neuroprotection afforded by naringin in CCL2-induced cognitive impairment in
rats. Before the CCL2 intra-hippocampal injection, rats were treated with
naringin for 3 consecutive days ...
Calcyon mRNA expression in the frontal-striatal circuitry and its relationship to vesicular processes and ADHD
Behavioral and Brain Functions - - 2007
No association of DRD2, DRD3, and tyrosine hydroxylase gene polymorphisms with personality traits in the Japanese population
Behavioral and Brain Functions - Tập 2 - Trang 1-5 - 2006
Dopamine D2 receptor (DRD2) and dopamine D3 receptor (DRD3) genes could be
candidates for personality-related genes considering their pharmacological
profiles or structures. However, a limited number of studies have investigated
the association between these genes and personality traits. In the present
study, we investigated the DRD2, DRD3, and tyrosine hydroxylase (TH) genes in
relation to person...
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