Genome-wide association studies of rheumatoid arthritis data via multiple hypothesis testing methods for correlated testsBMC Proceedings - Tập 3 - Trang 1-5 - 2009
Guolian Kang, Douglas K Childers, Nianjun Liu, Kui Zhang, Guimin Gao
Genome-wide association studies often involve testing hundreds of thousands of single-nucleotide polymorphisms (SNPs). These tests may be highly correlated because of linkage disequilibrium among SNPs. Multiple testing correction ignoring the correlation among markers, as is done in the Bonferroni procedure, can cause loss of power. Several multiple testing adjustment methods accounting for correl...... hiện toàn bộ
Comparison of analyses of the QTLMAS XII common dataset. I: Genomic selectionBMC Proceedings - Tập 3 - Trang 1-8 - 2009
Mogens Sandø Lund, Goutam Sahana, Dirk-Jan de Koning, Guosheng Su, Örjan Carlborg
A dataset was simulated and distributed to participants of the QTLMAS XII workshop who were invited to develop genomic selection models. Each contributing group was asked to describe the model development and validation as well as to submit genomic predictions for three generations of individuals, for which they only knew the genotypes. The organisers used these genomic predictions to perform the ...... hiện toàn bộ
Strengthening regulatory capacity for gene drives in Africa: leveraging NEPAD’s experience in establishing regulatory systems for medicines and GM crops in AfricaBMC Proceedings - Tập 12 - Trang 19-28 - 2018
Barbara Glover, Olalekan Akinbo, Moussa Savadogo, Samuel Timpo, Godwin Lemgo, Woldeyesus Sinebo, Sunday Akile, Silas Obukosia, Jeremy Ouedraogo, Margareth Ndomondo-Sigonda, Muffy Koch, Diran Makinde, Aggrey Ambali
The New Partnership for Africa’s Development (NEPAD) Agency recognizes that Africa is in a period of transition and that this demands exploring and harnessing safe advances made in science-based innovations including modern biotechnology. To advance the science of biotechnology in Africa effectively, while at the same time safeguarding human health and the environment, the African Union (AU) adopt...... hiện toàn bộ