BMC Gastroenterology
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Genomic profiling of a patient with quadruple synchronous colorectal cancer: a case report
BMC Gastroenterology - Tập 21 - Trang 1-5 - 2021
Synchronous colorectal cancer (SCRC) is featured by the presence of multiple primary tumor lesions in a single patient at initial diagnosis. It is less common with the prevalence of approximately 3.5% among colorectal cancer (CRC). Some studies of SCRC have been performed in patients with two tumor lesions. However, SCRC cases with three or more tumor lesions were rare and remained to be investiga...... hiện toàn bộ
Colon biopsies for evaluation of acute graft-versus-host disease (A-GVHD) in allogeneic bone marrow transplant patients
BMC Gastroenterology - Tập 3 - Trang 1-9 - 2003
Proper histomorphological interpretation of intestinal acute graft versus host disease (A-GVHD) associated with allogeneic bone marrow transplantation (BMT) is critical for clinical managaement. However, studies methodically evaluating different histomorphological features of A-GVHD are rare. Colonic biopsies from 44 allogeneic BMT patients having biopsy-proven cutaneous A-GVHD were compared with ...... hiện toàn bộ
Total cholesterol concentration predicts the effect of plasmapheresis on hypertriglyceridemic acute pancreatitis: a retrospective case–control study
BMC Gastroenterology - Tập 21 - Trang 1-9 - 2021
What kind of patients with hypertriglyceridemic acute pancreatitis (HLAP) might benefit from plasmapheresis (PP) remains unknown. The objective of this study is to determine the predict function of total cholesterol (TC) on the Triglyceride (TG)-lowing effect in patients on either non-PP or PP therapy.
Patients were categorized into high total cholesterol (HTC)/low total cholesterol (LTC) groups ...... hiện toàn bộ
Measurement of the total antioxidant response using a novel automated method in subjects with nonalcoholic steatohepatitis
BMC Gastroenterology - Tập 5 - Trang 1-6 - 2005
Oxidative stress, an increase in oxidants and/or a decrease in antioxidant capacity, is one of the potential biochemical mechanisms involved in the pathogenesis of nonalcoholic steatohepatitis. We aimed to investigate the total antioxidant response using a novel automated method in nonalcoholic steatohepatitis subjects. As a reciprocal measure, we also aimed to determine total peroxide level in th...... hiện toàn bộ
Mini-Mental State Examination in patients with hepatic encephalopathy and liver cirrhosis: a prospective, quantified electroencephalography study
BMC Gastroenterology - Tập 13 - Trang 1-7 - 2013
Mini-Mental State Examination (MMSE) is one of the most commonly used methods in the assessment of cognitive mental status. MMSE has been used in hepatology but its usefulness in the evaluation of hepatic encephalopathy (HE) has never been properly assessed. The aim of the study was to investigate the value of MMSE in detection of HE in patients with cirrhosis. One hundred and one consecutive pati...... hiện toàn bộ
A simple scoring model for advanced colorectal neoplasm in asymptomatic subjects aged 40–49 years
BMC Gastroenterology - Tập 17 - Trang 1-8 - 2017
Limited data are available for advanced colorectal neoplasm in asymptomatic individuals aged 40–49 years. We aimed to identify risk factors and develop a simple prediction model for advanced colorectal neoplasm in these persons. Clinical data were collected on 2781 asymptomatic subjects aged 40–49 years who underwent colonoscopy for routine health examination. Subjects were randomly allocated to a...... hiện toàn bộ
miRNA-338-3p/CDK4 signaling pathway suppressed hepatic stellate cell activation and proliferation
BMC Gastroenterology - Tập 17 - Trang 1-9 - 2017
Activated hepatic stellate cell (HSC) is the main fibrogenic cell type in the injured liver. miRNA plays an important role in activation and proliferation of HSC. Our previous study examined the expression profiles of microRNAs in quiescent and activated HSC. Real-time PCR and western blot were used to detect the expression of Collagen type I (Col 1) and Alpha-Smooth Muscle Actin (α-SMA). CCK-8 an...... hiện toàn bộ
Effect of bone marrow-derived mesenchymal stem cells on hepatic fibrosis in a thioacetamide-induced cirrhotic rat model
BMC Gastroenterology - Tập 14 - Trang 1-12 - 2014
Cirrhosis is a long-term consequence of chronic hepatic injury with fibrosis. No effective therapy is currently available for decompensated cirrhosis except liver transplantation. Hence, we investigated the effect of bone marrow-derived mesenchymal stem cells (BM-MSCs) on hepatic fibrosis in a thioacetamide (TAA)-induced cirrhotic rat model. The BM-MSCs were injected directly into the right liver ...... hiện toàn bộ
Clinical characteristics and treatment outcomes of primary malignant melanoma of esophagus: a single center experience
BMC Gastroenterology - Tập 22 - Trang 1-10 - 2022
Primary malignant melanoma of esophagus (PMME) is an extremely rare disease with poor prognosis. We aimed to determine the clinical characteristics and treatment outcomes of patients with PMME. We retrospectively reviewed 17 patients diagnosed with PMME in Samsung Medical Center between 2000 and 2020 with median 34 months of follow-up. Survival outcomes were analyzed with Kaplan–Meier method. 15 p...... hiện toàn bộ
Chronic active EBV infection in refractory enteritis with longitudinal ulcers with a cobblestone appearance: an autopsied case report
BMC Gastroenterology - Tập 21 - Trang 1-7 - 2021
Chronic active Epstein–Barr virus infection (CAEBV) is defined as Epstein–Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious mononucleocytosis, whereas enteritis and diarrhea are minor clinical symptoms. The complex mixture of tumorigenic processes of EBV-positive cells and physical symptoms of systemic inflammato...... hiện toàn bộ
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