Arthritis and Rheumatology
SCOPUS (2014-2025)SCIE-ISI
2326-5191
2326-5205
Anh Quốc
Cơ quản chủ quản: WILEY , John Wiley and Sons Ltd
Lĩnh vực:
ImmunologyRheumatologyImmunology and Allergy
Các bài báo tiêu biểu
2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data‐Driven Methodology Involving Three International Patient Cohorts
Tập 69 Số 1 - Trang 35-45 - 2017
ObjectiveTo develop and validate an international set of classification criteria
for primary Sjögren's syndrome (SS) using guidelines from the American College
of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). These
criteria were developed for use in individuals with signs and/or symptoms
suggestive of SS.MethodsWe assigned preliminary importance weights to a
consensus list...
2017 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Adult and Juvenile Idiopathic Inflammatory Myopathies and Their Major Subgroups
Tập 69 Số 12 - Trang 2271-2282 - 2017
ObjectiveTo develop and validate new classification criteria for adult and
juvenile idiopathic inflammatory myopathies (IIM) and their major
subgroups.MethodsCandidate variables were assembled from published criteria and
expert opinion using consensus methodology. Data were collected from 47
rheumatology, dermatology, neurology, and pediatric clinics worldwide. Several
statistical methods were uti...
Release of Neutrophil Extracellular Traps by Neutrophils Stimulated With Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome
Tập 67 Số 11 - Trang 2990-3003 - 2015
ObjectiveAntiphospholipid antibodies (aPL), especially those targeting
β2‐glycoprotein I (β2GPI), are well known to activate endothelial cells,
monocytes, and platelets, with prothrombotic implications. In contrast, the
interaction of aPL with neutrophils has not been extensively studied. Neutrophil
extracellular traps (NETs) have recently been recognized as an important
activator of the coagulati...
18F‐Fluorodeoxyglucose–Positron Emission Tomography As an Imaging Biomarker in a Prospective, Longitudinal Cohort of Patients With Large Vessel Vasculitis
Tập 70 Số 3 - Trang 439-449 - 2018
ObjectiveTo assess the clinical value of18F‐fluorodeoxyglucose (FDG) positron
emission tomography (PET) in a prospective cohort of patients with large vessel
vasculitis (LVV) and comparator subjects.MethodsPatients with Takayasu arteritis
and giant cell arteritis were studied, along with a comparator group consisting
of patients with hyperlipidemia, patients with diseases that mimicLVV, and
health...
Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof‐of‐Concept Trial of Metformin
Tập 67 Số 12 - Trang 3190-3200 - 2015
ObjectiveNeutrophil extracellular traps (NETs) have been shown to play an
important role in systemic lupus erythematosus (SLE) pathogenesis by activating
plasmacytoid dendritic cells (PDCs) and the type I interferon (IFN) pathway.
NETs composed of self‐DNA are considered to be of nuclear origin and are a major
source of anti‐DNA autoantibody generation. This study was undertaken to
evaluate whethe...
Three Multicenter, Randomized, Double‐Blind, Placebo‐Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis
Tập 71 Số 2 - Trang 258-270 - 2019
ObjectiveTo evaluate the efficacy and safety of ustekinumab in 3 randomized,
placebo‐controlled studies in patients with axial spondyloarthritis (SpA).
Studies 1 and 2 included patients with radiographic axial SpA (anti–tumor
necrosis factor [anti‐TNF]–naive patients and patients with inadequate response
or intolerance to anti‐TNF, respectively); study 3 patients had nonradiographic
axial SpA.Meth...
Intraarticular Sprifermin (Recombinant Human Fibroblast Growth Factor 18) in Knee Osteoarthritis: A Randomized, Double‐Blind, Placebo‐Controlled Trial
Tập 66 Số 7 - Trang 1820-1831 - 2014
ObjectiveTo evaluate the efficacy and safety of intraarticular sprifermin
(recombinant human fibroblast growth factor 18) in the treatment of symptomatic
knee osteoarthritis (OA).MethodsThe study was a randomized, double‐blind,
placebo‐controlled, proof‐of‐concept trial. Intraarticular sprifermin was
evaluated at doses of 10 μg, 30 μg, and 100 μg. The primary efficacy end point
was change in centr...
Inhibition of Natural Killer Cell Cytotoxicity by Interleukin‐6: Implications for the Pathogenesis of Macrophage Activation Syndrome
Tập 67 Số 11 - Trang 3037-3046 - 2015
ObjectiveSystemic juvenile idiopathic arthritis (JIA) is associated with high
levels of interleukin‐6 (IL‐6) in the serum and synovial fluid, and impairment
of natural killer (NK) cell function is often observed. This study was
undertaken to evaluate a possible link between these 2 biologic findings and
whether they may be associated with the development of macrophage activation
syndrome, a condit...
Review: Synovial Cell Metabolism and Chronic Inflammation in Rheumatoid Arthritis
Tập 70 Số 7 - Trang 984-999 - 2018
Metabolomic studies of body fluids show that immune‐mediated inflammatory
diseases such as rheumatoid arthritis (RA) are associated with metabolic
disruption. This is likely to reflect the increased bioenergetic and
biosynthetic demands of sustained inflammation and changes in nutrient and
oxygen availability in damaged tissue. The synovial membrane lining layer is the
principal site of inflammati...
Effectiveness of First‐Line Treatment With Recombinant Interleukin‐1 Receptor Antagonist in Steroid‐Naive Patients With New‐Onset Systemic Juvenile Idiopathic Arthritis: Results of a Prospective Cohort Study
Tập 66 Số 4 - Trang 1034-1043 - 2014
ObjectiveTo conduct a prospective cohort study using anakinra, a recombinant
IL‐1 receptor antagonist (IL‐1Ra), as first‐line therapy in patients with
new‐onset systemic juvenile idiopathic arthritis (JIA).MethodsTherapy with
recombinant IL‐1Ra (2 mg/kg) was initiated in 20 patients who fulfilled the
International League of Associations for Rheumatology criteria for systemic JIA,
before systemic s...