Arthritis and Rheumatology

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Interferon Regulatory Factor 1 Marks Activated Genes and Can Induce Target Gene Expression in Systemic Lupus Erythematosus
Arthritis and Rheumatology - Tập 67 Số 3 - Trang 785-796 - 2015
Zhe Zhang, Lihua Shi, Li Song, Elshaddai Ephrem, Michelle Petri, Kathleen E. Sullivan
ObjectiveInterferon regulatory factor 1 (IRF‐1) mediates both induction of interferons (IFNs) and responses to type I IFNs. It has been implicated as a critical mediator of inflammation in murine lupus models. In a previous study of chromatin modifications in monocytes from patients with systemic lupus erythematosus (SLE), IRF‐1 was implicated as being as...... hiện toàn bộ
Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross‐Disease Meta‐Analysis of Genome‐Wide Association Studies
Arthritis and Rheumatology - Tập 68 Số 9 - Trang 2338-2344 - 2016
Elena López‐Isac, Javier Martı́n, Shervin Assassi, Carmen Pilar Simeón‐Aznar, Patrícia Carreira, Norbérto Ortego-Centeno, M. Freire, E. Beltrán, Javier Narváez, Juan José Alegre Sancho, Antonio Fernández‐Nebro, Alejandro Balsa, Ana M. Ortiz, Miguel Á. González‐Gay, Lorenzo Beretta, Alessandro Santaniello, Chiara Bellocchi, Claudio Lunardi, Gianluca Moroncini, Tianlu Li, Torsten Witte, Nicolas Hunzelmann, Jörg H. W. Distler, Gabriella Riekemasten, Annette H M van der Helm–van Mil, Jeska de Vries‐Bouwstra, César Magro‐Checa, Alexandre E. Voskuyl, Alfredo Castillo, Øyvind Molberg, Tony R. Merriman, Roger Hesselstrand, Annica Nordin, Leonid Padyukov, Ariane L. Herrick, Stephen E. Epstein, Christopher P. Denton, Carmen Fonseca, Timothy R. D. J. Radstake, Jane Worthington, Maureen D. Mayes
ObjectiveSystemic sclerosis (SSc) and rheumatoid arthritis (RA) are autoimmune diseases that have similar clinical and immunologic characteristics. To date, several shared SSc–RA genetic loci have been identified independently. The aim of the current study was to systematically search for new common SSc–RA loci through an interdisease meta–genome‐wide ass...... hiện toàn bộ
2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data‐Driven Methodology Involving Three International Patient Cohorts
Arthritis and Rheumatology - Tập 69 Số 1 - Trang 35-45 - 2017
Caroline H. Shiboski, Stephen Shiboski, Raphaèle Séror, Lindsey A. Criswell, Marc Labétoulle, Thomas M. Lietman, Astrid Rasmussen, R. Hal Scofield, Claudio Vitali, Simon Bowman, Xavier Mariette
ObjectiveTo develop and validate an international set of classification criteria for primary Sjögren's syndrome (SS) using guidelines from the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). These criteria were developed for use in individuals with signs and/or symptoms suggestive of SS.... hiện toàn bộ
Nonsteroidal Antiinflammatory Drugs and Susceptibility to COVID‐19
Arthritis and Rheumatology - Tập 73 Số 5 - Trang 731-739 - 2021
Joht Singh Chandan, Dawit T. Zemedikun, Rasiah Thayakaran, Nathan Byne, Samir Dhalla, Dionisio Acosta, Krishna Gokhale, Tom Thomas, Christopher Sainsbury, Anuradhaa Subramanian, Jennifer Cooper, Astha Anand, Kelvin Okoth, Jingya Wang, Nicola J. Adderley, Thomas Taverner, Alastair K. Denniston, Janet M. Lord, G. Neil Thomas, Christopher D. Buckley, Karim Raza, Neeraj Bhala, Krishnarajah Nirantharakumar, Shamil Haroon
ObjectiveTo identify whether active use of nonsteroidal antiinflammatory drugs (NSAIDs) increases susceptibility to developing suspected or confirmed coronavirus disease 2019 (COVID‐19) compared to the use of other common analgesics.MethodsWe performed a propensity score–matched cohort study w...... hiện toàn bộ
Inhibition of Natural Killer Cell Cytotoxicity by Interleukin‐6: Implications for the Pathogenesis of Macrophage Activation Syndrome
Arthritis and Rheumatology - Tập 67 Số 11 - Trang 3037-3046 - 2015
Loredana Cifaldi, Giusi Prencipe, Ivan Caiello, Claudia Bracaglia, Franco Locatelli, Fabrizio De Benedetti, Raffaele Strippoli
ObjectiveSystemic juvenile idiopathic arthritis (JIA) is associated with high levels of interleukin‐6 (IL‐6) in the serum and synovial fluid, and impairment of natural killer (NK) cell function is often observed. This study was undertaken to evaluate a possible link between these 2 biologic findings and whether they may be associated with the development ...... hiện toàn bộ
JAK/STAT Blockade Alters Synovial Bioenergetics, Mitochondrial Function, and Proinflammatory Mediators in Rheumatoid Arthritis
Arthritis and Rheumatology - Tập 70 Số 12 - Trang 1959-1970 - 2018
Trudy McGarry, Carl Orr, S Wade, Monika Biniecka, Laura Gallagher, Candice Low, Douglas J. Veale, Ursula Fearon
ObjectiveTo examine the effects of tofacitinib on metabolic activity, mitochondrial function, and proinflammatory mechanisms in rheumatoid arthritis (RA).MethodsEx vivo RA... hiện toàn bộ
Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus
Arthritis and Rheumatology - Tập 69 Số 5 - Trang 1028-1034 - 2017
Victoria P. Werth, David Fiorentino, Barbara Sullivan, Michael Boedigheimer, Kit Chiu, Christine Wang, Gregory E. Arnold, Michael A. Damore, Jeannette Bigler, Andrew A. Welcher, Chris B. Russell, David A. Martin, James B. Chung
ObjectiveInterferon‐γ (IFNγ) is implicated in the pathogenesis of discoid lupus erythematosus (DLE). This study sought to evaluate a single dose of AMG 811, an anti‐IFNγ antibody, in patients with DLE.MethodsThe study was designed as a phase I randomized, double‐blind, placebo‐controlled cross...... hiện toàn bộ
Ultraviolet B Irradiation Causes Stimulator of Interferon Genes–Dependent Production of Protective Type I Interferon in Mouse Skin by Recruited Inflammatory Monocytes
Arthritis and Rheumatology - Tập 69 Số 4 - Trang 826-836 - 2017
Clayton Sontheimer, Denny Liggitt, Keith B. Elkon
ObjectivePhotosensitivity is common in patients with systemic lupus erythematosus, although the mechanisms linking ultraviolet (UV) light to flares are not well understood. We undertook this study to determine whether repetitive UVB exposure could induce type I interferon (IFN) production in normal mouse skin, and to investigate the roles of inflammatory ...... hiện toàn bộ
Racial and Ethnic Differences in Older Adults With Knee Osteoarthritis
Arthritis and Rheumatology - Tập 66 Số 7 - Trang 1800-1810 - 2014
Yenisel Cruz‐Almeida, Kimberly T. Sibille, Burel R. Goodin, Megan E. Petrov, Emily J. Bartley, Joseph L. Riley, Christopher D. King, Toni L. Glover, Adriana Sotolongo, Matthew S. Herbert, J. Schmidt, Barri J. Fessler, Roland Staud, David T. Redden, Laurence A. Bradley, Roger B. Fillingim
ObjectiveKnee osteoarthritis (OA) contributes significantly to disability in older individuals, and racial/ethnic minorities are disproportionately affected. The present study aimed to characterize differences in clinical and experimental pain, including pain inhibition, among older African American (AA) and non‐Hispanic white (NHW) subjects with knee OA....... hiện toàn bộ
Intraarticular Sprifermin (Recombinant Human Fibroblast Growth Factor 18) in Knee Osteoarthritis: A Randomized, Double‐Blind, Placebo‐Controlled Trial
Arthritis and Rheumatology - Tập 66 Số 7 - Trang 1820-1831 - 2014
Stefan Lohmander, Scarlett Hellot, Don Dreher, Eduard F. W. Krantz, Dawie Kruger, Ali Guermazi, F. Eckstein
ObjectiveTo evaluate the efficacy and safety of intraarticular sprifermin (recombinant human fibroblast growth factor 18) in the treatment of symptomatic knee osteoarthritis (OA).MethodsThe study was a randomized, double‐blind, placebo‐controlled, proof‐of‐concept trial. Intraarticular sprifer...... hiện toàn bộ
Tổng số: 53   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6