Neurodegenerative TauopathiesAnnual Review of Neuroscience - Tập 24 Số 1 - Trang 1121-1159 - 2001
Virginia M.‐Y. Lee, Michel Goedert, John Q. Trojanowski
▪ Abstract The defining neuropathological characteristics of Alzheimer's disease are abundant filamentous tau lesions and deposits of fibrillar amyloid β peptides. Prominent filamentous tau inclusions and brain degeneration in the absence of β-amyloid deposits are also hallmarks of neurodegenerative tauopathies exemplified by sporadic corticobasal degeneration, progressive supranuclear pa...... hiện toàn bộ
Intentional Maps in Posterior Parietal CortexAnnual Review of Neuroscience - Tập 25 Số 1 - Trang 189-220 - 2002
Richard A. Andersen, Christopher A. Buneo
▪ Abstract The posterior parietal cortex (PPC), historically believed to be a sensory structure, is now viewed as an area important for sensory-motor integration. Among its functions is the forming of intentions, that is, high-level cognitive plans for movement. There is a map of intentions within the PPC, with different subregions dedicated to the planning of eye movements, reaching move...... hiện toàn bộ
Protein Synthesis at Synaptic Sites on DendritesAnnual Review of Neuroscience - Tập 24 Số 1 - Trang 299-325 - 2001
Oswald Steward, Erin M. Schuman
▪ Abstract Studies over the past 20 years have revealed that gene expression in neurons is carried out by a distributed network of translational machinery. One component of this network is localized in dendrites, where polyribosomes and associated membranous elements are positioned beneath synapses and translate a particular population of dendritic mRNAs. The localization of translation ...... hiện toàn bộ
Establishment of Axon-Dendrite Polarity in Developing NeuronsAnnual Review of Neuroscience - Tập 32 Số 1 - Trang 347-381 - 2009
Anthony P. Barnes, Franck Polleux
Neurons are among the most highly polarized cell types in the body, and the polarization of axon and dendrites underlies the ability of neurons to integrate and transmit information in the brain. Significant progress has been made in the identification of the cellular and molecular mechanisms underlying the establishment of neuronal polarity using primarily in vitro approaches such as dis...... hiện toàn bộ
THE PLASTIC HUMAN BRAIN CORTEXAnnual Review of Neuroscience - Tập 28 Số 1 - Trang 377-401 - 2005
Álvaro Pascual‐Leone, Amir Amedi, Felipe Fregni, Lotfi B. Merabet
Plasticity is an intrinsic property of the human brain and represents evolution's invention to enable the nervous system to escape the restrictions of its own genome and thus adapt to environmental pressures, physiologic changes, and experiences. Dynamic shifts in the strength of preexisting connections across distributed neural networks, changes in task-related cortico-cortical and corti...... hiện toàn bộ
Plasticity of Cortical Excitatory-Inhibitory BalanceAnnual Review of Neuroscience - Tập 38 Số 1 - Trang 195-219 - 2015
Robert C. Froemke
Synapses are highly plastic and are modified by changes in patterns of neural activity or sensory experience. Plasticity of cortical excitatory synapses is thought to be important for learning and memory, leading to alterations in sensory representations and cognitive maps. However, these changes must be coordinated across other synapses within local circuits to preserve neural coding sch...... hiện toàn bộ
Endogenous Opioids: Biology and FunctionAnnual Review of Neuroscience - Tập 7 Số 1 - Trang 223-255 - 1984
Huda Akil, Stanley J. Watson, Elizabeth A. Young, Michael E. Lewis, Henry Khachaturian, James M. Walker
The Perirhinal CortexAnnual Review of Neuroscience - Tập 37 Số 1 - Trang 39-53 - 2014
Wendy Suzuki, Yuji Naya
Anatomically, the perirhinal cortex sits at the boundary between the medial temporal lobe and the ventral visual pathway. It has prominent interconnections not only with both these systems, but also with a wide range of unimodal and polymodal association areas. Consistent with these diverse projections, neurophysiological studies reveal a multidimensional set of mnemonic signals that incl...... hiện toàn bộ