CRITICAL PERIOD REGULATIONAnnual Review of Neuroscience - Tập 27 Số 1 - Trang 549-579 - 2004
Takao K. Hensch
▪ Abstract Neuronal circuits are shaped by experience during critical periods of early postnatal life. The ability to control the timing, duration, and closure of these heightened levels of brain plasticity has recently become experimentally accessible, especially in the developing visual system. This review summarizes our current understanding of known critical periods across several sys...... hiện toàn bộ
Neurodegenerative TauopathiesAnnual Review of Neuroscience - Tập 24 Số 1 - Trang 1121-1159 - 2001
Virginia M.‐Y. Lee, Michel Goedert, John Q. Trojanowski
▪ Abstract The defining neuropathological characteristics of Alzheimer's disease are abundant filamentous tau lesions and deposits of fibrillar amyloid β peptides. Prominent filamentous tau inclusions and brain degeneration in the absence of β-amyloid deposits are also hallmarks of neurodegenerative tauopathies exemplified by sporadic corticobasal degeneration, progressive supranuclear pa...... hiện toàn bộ
Neural Coding of Uncertainty and ProbabilityAnnual Review of Neuroscience - Tập 37 Số 1 - Trang 205-220 - 2014
Wei Ji, Mehrdad Jazayeri
Organisms must act in the face of sensory, motor, and reward uncertainty stemming from a pandemonium of stochasticity and missing information. In many tasks, organisms can make better decisions if they have at their disposal a representation of the uncertainty associated with task-relevant variables. We formalize this problem using Bayesian decision theory and review recent behavioral and...... hiện toàn bộ
Intentional Maps in Posterior Parietal CortexAnnual Review of Neuroscience - Tập 25 Số 1 - Trang 189-220 - 2002
Richard A. Andersen, Christopher A. Buneo
▪ Abstract The posterior parietal cortex (PPC), historically believed to be a sensory structure, is now viewed as an area important for sensory-motor integration. Among its functions is the forming of intentions, that is, high-level cognitive plans for movement. There is a map of intentions within the PPC, with different subregions dedicated to the planning of eye movements, reaching move...... hiện toàn bộ