Stanley J. Sarnoff, Eugene Braunwald, G. H. Welch, Robert B. Case, W. N. Stainsby, R Macrúz
The hemodynamic determinants of myocardial oxygen utilization were ascertained in the isolated, metabolically supported, nonfailing canine heart. The primary determinant was found to be the total tension developed by the myocardium as indicated by the area beneath the systolic pressure curve (Tension-Time Index). The significance of these findings for the understanding of the low efficien...... hiện toàn bộ
H. Stanley Bennett, John H. Luft, James C. Hampton
Morphological features of blood capillaries from various vertebrate forms and organs are presented. Simple classifications are proposed, based on presence or absence of continuous basement membrane, on the nature of the endothelial cell and on the presence or absence of a complete investment of pericapillary cells. It is suggested that these varying capillary structural features may be re...... hiện toàn bộ
The percentages of 22 14C-labeled amino acids remaining in rat brain 15 s after carotid injection were measured relative to a simultaneously injected diffusible internal standard, 3HOH. The injected solution also contained a nondiffusible internal standard, [113mIn]EDTA to correct for incomplete brain blood compartment washout. Self-inhibition and cross-inhibition was demonstrated by incl...... hiện toàn bộ
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