Stanley J. Sarnoff, Eugene Braunwald, G. H. Welch, Robert B. Case, W. N. Stainsby, R Macrúz
The hemodynamic determinants of myocardial oxygen utilization were ascertained
in the isolated, metabolically supported, nonfailing canine heart. The primary
determinant was found to be the total tension developed by the myocardium as
indicated by the area beneath the systolic pressure curve (Tension-Time Index).
The significance of these findings for the understanding of the low efficiency
of the... hiện toàn bộ
H. Stanley Bennett, John H. Luft, James C. Hampton
Morphological features of blood capillaries from various vertebrate forms and
organs are presented. Simple classifications are proposed, based on presence or
absence of continuous basement membrane, on the nature of the endothelial cell
and on the presence or absence of a complete investment of pericapillary cells.
It is suggested that these varying capillary structural features may be relevant
to... hiện toàn bộ
The percentages of 22 14C-labeled amino acids remaining in rat brain 15 s after
carotid injection were measured relative to a simultaneously injected diffusible
internal standard, 3HOH. The injected solution also contained a nondiffusible
internal standard, [113mIn]EDTA to correct for incomplete brain blood
compartment washout. Self-inhibition and cross-inhibition was demonstrated by
inclusion of ... hiện toàn bộ