American Journal of Rhinology and Allergy

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The Impact of Biofilms on Outcomes after Endoscopic Sinus Surgery
American Journal of Rhinology and Allergy - Tập 24 Số 3 - Trang 169-174 - 2010
Deepti Singhal, Alkis J. Psaltis, Andrew Foreman, Peter‐John Wormald
Background Although biofilms have been implicated in the pathogenesis of chronic rhinosinusitis (CRS), there is little evidence that their presence or absence has any effect on the outcomes of endoscopic sinus surgery (ESS). The aim of this study was to investigate the effect of biofilms on postsurgical outcomes after ESS. Methods A prospective, blinded study of 51 consecutive patients undergoing ... hiện toàn bộ
Characterization of Bacterial and Fungal Biofilms in Chronic Rhinosinusitis
American Journal of Rhinology and Allergy - Tập 23 Số 6 - Trang 556-561 - 2009
Andrew Foreman, Alkis J. Psaltis, Lor Wai Tan, Peter‐John Wormald
Background Conclusive evidence exists that biofilms are present on the mucosa of chronic rhinosinusitis (CRS) patients. Less is known about the species constituting these biofilms. This study developed a fluorescence in situ hybridization (FISH) protocol for characterization of bacterial and fungal biofilms in CRS. Methods Fifty CRS patients and 10 controls were recruited. Bacteria FISH probes for... hiện toàn bộ
Biofilms and Mucosal Healing in Postsurgical Patients with Chronic Rhinosinusitis
American Journal of Rhinology and Allergy - Tập 23 Số 5 - Trang 506-511 - 2009
Zhang Zi, Demin Han, Shengzhong Zhang, Yehua Han, Wei Dai, Erzhong Fan, Ying Li, Yunchuan Li, De Yun Wang
Background Patients with chronic rhinosinusitis (CRS) often remain symptomatic after technically proficient functional endoscopic sinus surgery. Current hypothesis indicates biofilms may contribute to the persistence of infection. However, few studies showed biofilms in postoperative patients. This study was designed to identify bacterial biofilms on postoperative mucosa, as well as to investigate... hiện toàn bộ
Critical Appraisal and Meta-Analysis of Nasal Surgery for Obstructive Sleep Apnea
American Journal of Rhinology and Allergy - Tập 25 Số 1 - Trang 45-49 - 2011
Hsueh‐Yu Li, Pa‐Chun Wang, Yu‐Pin Chen, Li‐Ang Lee, Tuan‐Jen Fang, Hsin‐Ching Lin
Background Nasal surgery is commonly involved in surgical treatment for obstructive sleep apnea (OSA). The aim of this study was to investigate the outcomes of nasal surgery for OSA using evidence-based methodology. Methods The MedLine database (1999∼2009) was searched for original articles published in peer-reviewed journals concerning nasal surgery for snoring/sleep apnea. Data extracted from th... hiện toàn bộ
No Mucosal Atrophy and Reduced Inflammatory Cells: Active-controlled Trial with Yearlong Fluticasone Furoate Nasal Spray
American Journal of Rhinology and Allergy - Tập 26 Số 1 - Trang 36-44 - 2012
Wytske J. Fokkens, Bas Rinia, Cornelis M. van Drunen, Peter W. Hellings, Greet Hens, A.P. Jansen, Henk M. Blom, Wei Wu, Diane Clements, Laurie A. Lee, E. Philpot
Background Fluticasone furoate nasal spray (FFNS) and mometasone furoate nasal spray (MFNS) are well tolerated and more effective than placebo at relieving the symptoms of seasonal and perennial allergic rhinitis. Effects of FFNS on the nasal histology have not been previously reported. This study examines the effects of FFNS and MFNS, administered daily for 1 year, on the nasal mucosa in subjects... hiện toàn bộ
Detection of Surfactant Proteins A, B, C, and D in Human Nasal Mucosa and Their Regulation in Chronic Rhinosinusitis with Polyps
American Journal of Rhinology and Allergy - Tập 27 Số 1 - Trang 24-29 - 2013
Martin Schicht, Stephan Knipping, Robert P. Hirt, Stephanie Beileke, Saadettin Sel, Friedrich Paulsen, Lars Bräuer
Backround The nasal mucosa is characterized by a multirow high prismatic ciliated epithelium representing the first barrier of the immune defense system against microbial and other environmental pathogenic influences. A number of nonspecific defense mechanisms, including the presence of lactoferrin, peroxidases, proteases, interferons, and lysozymes in nasal secretions, act to counter inflammatory... hiện toàn bộ
Chitin Stimulates Expression of Acidic Mammalian Chitinase and Eotaxin-3 by Human Sinonasal Epithelial Cells in Vitro
American Journal of Rhinology and Allergy - Tập 23 Số 1 - Trang 8-14 - 2009
Ashley Lalaker, Louis J. Nkrumah, Won-Kyung Lee, Murugappan Ramanathan, Andrew P. Lane
Background Sinonasal epithelial cells participate in host defense by initiating innate immune mechanisms against potential pathogens. Antimicrobial innate mechanisms have been shown to involve Th1-like inflammatory responses. Although epithelial cells can also be induced by Th2 cytokines to express proeosinophilic mediators, no environmental agents have been identified that promote this effect. Me... hiện toàn bộ
The Role of Fungi in Diseases of the Nose and Sinuses
American Journal of Rhinology and Allergy - Tập 26 Số 5 - Trang 351-358 - 2012
Zachary M. Soler, Rodney J. Schlosser
Background Human exposure to fungal elements is inevitable, with normal respiration routinely depositing fungal hyphae within the nose and paranasal sinuses. Fungal species can cause sinonasal disease, with clinical outcomes ranging from mild symptoms to intracranial invasion and death. There has been much debate regarding the precise role fungal species play in sinonasal disease and optimal treat... hiện toàn bộ
Causes of Dacryocystorhinostomy Failure: External versus Endoscopic Approach
American Journal of Rhinology and Allergy - Tập 31 Số 3 - Trang 181-185 - 2017
Giant Lin, Christopher Brook, Mark P. Hatton, Ralph Metson
Objectives To compare the causes of failure between external and endoscopic dacryocystorhinostomy (DCR) techniques for the treatment of lacrimal obstruction. Study Design A retrospective cohort study. Methods The study population consisted of 53 consecutive patients who underwent revision endoscopic DCR from 2002 to 2013 for lacrimal duct obstruction. Identified causes of previous DCR failure were... hiện toàn bộ
Primary Endoscopic Dacryocystorhinostomy with or without Silicone Tubing: A Prospective Randomized Study
American Journal of Rhinology and Allergy - Tập 26 Số 4 - Trang 332-334 - 2012
Ali S Al-Qahtani
Background Endoscopic dacryocystorhinostomy (DCR) is an effective surgical procedure to treat saccal and postsaccal stenosis or nasolacrimal duct obstruction. The use of silicone tube after endoscopic DCR is still controversial. A prospective randomized study was conducted to compare the success rate between the use of silicone stent and no use of silicone stent in endoscopic DCR. Methods A prospe... hiện toàn bộ
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