American Journal of Hematology

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Kinetic analysis in single, intact cells by microspectrophotometry: Evidence for two populations of erythrocytes in an individual heterozygous for glucose‐6‐phosphate dehydrogenase deficiency
American Journal of Hematology - Tập 23 Số 4 - Trang 311-316 - 1986
Richard A. Ashmun, Donald E. Hultquist, Jerome S. Schultz
AbstractA microspectrophotometric technique was used to measure the kinetics of methemoglobin reduction in intact, unaltered human erythrocytes. Reduction was catalyzed by endogenous NADPH‐methemoglobin reductase in the presence of Nile Blue. The technique was applied to the study of erythrocytes from a female donor with decreased glucose‐6‐phosphate dehydrogenase (G‐6‐PD) activity. The individual... hiện toàn bộ
Immune thrombocytopenia due to COVID‐19 during pregnancy
American Journal of Hematology - Tập 95 Số 8 - 2020
Man Tang, Erfan Nur, Bart J. Biemond
Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions
American Journal of Hematology - Tập 84 Số 9 - Trang 618-625 - 2009
Gregory J. Kato, Robert P. Hebbel, Martin H. Steinberg, Mark T. Gladwin
Hydroxyurea adherence and associated outcomes among Medicaid enrollees with sickle cell disease
American Journal of Hematology - Tập 86 Số 3 - Trang 273-277 - 2011
Sean D. Candrilli, Sarah H. O’Brien, Russell E. Ware, Milap C. Nahata, Eric E. Seiber, Rajesh Balkrishnan
AbstractWhile laboratory and clinical benefits of hydroxyurea for patients with sickle cell disease (SCD) are well‐established, few data describe the extent and implications of non‐adherence. We sought to assess adherence to hydroxyurea among patients with SCD and investigate associations between adherence and clinical and economic outcomes. Insurance claims of North Carolina Medicaid enrollees (6... hiện toàn bộ
Alpha thalassemia and stroke risk in sickle cell anemia
American Journal of Hematology - Tập 45 Số 4 - Trang 279-282 - 1994
Robert Adams, Abdullah Kutlar, Virgil McKie, Elizabeth Carl, Fenwick T. Nichols, Jin Cal Liu, Kathleen T. McKie, A.R. Clary
AbstractIn an effort to identify possible risk factors for stroke in Sickle Cell Anemia (Hb SS), we analyzed the distribution of alpha‐globin gene deletions in a group of Hb SS patients with and without stroke. The group with stroke consisted of 44 patients, (27 male, 17 female) with a mean of 7.5 years at time of stroke. The control group (non‐stroke) had 256 Hb SS patients (126 male, 130 female)... hiện toàn bộ
Is splenectomy still the gold standard for the treatment of chronic ITP?
American Journal of Hematology - Tập 83 Số 2 - Trang 91-91 - 2008
Francesco Rodeghiero, Marco Ruggeri
The direct antiglobulin test: A critical step in the evaluation of hemolysis
American Journal of Hematology - Tập 87 Số 7 - Trang 707-709 - 2012
Nicole D. Zantek, Scott A. Koepsell, Daryl R. Tharp, Claudia S. Cohn
AbstractThe direct antiglobulin test (DAT) is a laboratory test that detects immunoglobulin and/or complement on the surface of red blood cells. The utility of the DAT is to sort hemolysis into an immune or nonimmune etiology. As with all tests, DAT results must be viewed in light of clinical and other laboratory data. This review highlights the most common clinical situations where the DAT can he... hiện toàn bộ
Factor VII deficiency
American Journal of Hematology - Tập 10 Số 1 - Trang 79-88 - 1981
Margaret V. Ragni, Jessica H. Lewis, Joel A. Spero, Ute Hasiba
AbstractThis report describes three patients with factor (F) VII deficiency: two adult siblings and an unrelated 5½‐month‐old child who succumbed after several central nervous system (CNS) hemorrhages. This event prompted a review of the literature concerning the incidence and characteristics of intracranial hemorrhage in congenital F VII deficiency.Of 138 patients reported to have F VII deficienc... hiện toàn bộ
Increasing mortality from thrombotic thrombocytopenic purpura in the United States—analysis of national mortality data, 1968–1991
American Journal of Hematology - Tập 50 Số 2 - Trang 84-90 - 1995
Thomas J. Török, Robert C. Holman, Terence Chorba
AbstractThrombotic thrombocytopenic purpura (TTP) is a rare disease and the epidemiologic features have been incompletely characterized. Because of the historically high case‐fatality rate for TTP, we analyzed U.S. multiple cause‐of‐death mortality data with TTP listed on the death record for the period 1968–1991, in order to estimate the incidence of TTP, to characterize demographic features of t... hiện toàn bộ
Estimated annual numbers of US acute‐care hospital patients at risk for venous thromboembolism
American Journal of Hematology - Tập 82 Số 9 - Trang 777-782 - 2007
Frederick A. Anderson, Maxim Zayaruzny, John A. Heit, Dogan Fidan, Alexander T. Cohen
AbstractVenous thromboembolism (VTE) is a major US health problem. However, the total number of US inpatients who are at risk for VTE is unknown. Our objective was to estimate the number of US acute‐care hospital inpatients who were at risk for VTE according to criteria established by the Seventh American College of Chest Physicians (ACCP) Consensus Conference on Antithrombotic and Thrombolytic Th... hiện toàn bộ
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