Hydroxyurea adherence and associated outcomes among Medicaid enrollees with sickle cell diseaseAmerican Journal of Hematology - Tập 86 Số 3 - Trang 273-277 - 2011
Sean D. Candrilli, Sarah H. O’Brien, Russell E. Ware, Milap C. Nahata, Eric E. Seiber, Rajesh Balkrishnan
AbstractWhile laboratory and clinical benefits of hydroxyurea for patients with sickle cell disease (SCD) are well‐established, few data describe the extent and implications of non‐adherence. We sought to assess adherence to hydroxyurea among patients with SCD and investigate associations between adherence and clinical and economic outcomes. Insurance claims of Nor...... hiện toàn bộ
Alpha thalassemia and stroke risk in sickle cell anemiaAmerican Journal of Hematology - Tập 45 Số 4 - Trang 279-282 - 1994
Robert Adams, Abdullah Kutlar, Virgil McKie, Elizabeth Carl, Fenwick T. Nichols, Jin Cal Liu, Kathleen T. McKie, A.R. Clary
AbstractIn an effort to identify possible risk factors for stroke in Sickle Cell Anemia (Hb SS), we analyzed the distribution of alpha‐globin gene deletions in a group of Hb SS patients with and without stroke. The group with stroke consisted of 44 patients, (27 male, 17 female) with a mean of 7.5 years at time of stroke. The control group (non‐stroke) had 256 Hb S...... hiện toàn bộ
Mitral valve prolapse in sickle cell disease: Manifestation of a generalized connective tissue disorderAmerican Journal of Hematology - Tập 19 Số 1 - Trang 1-12 - 1985
Scott M. Lippman, R. Patrick Abergel, Leonard E. Ginzton, Jouni Uitto, Kouichi R. Tanaka, Eishichi Miyamoto, Michael M. Laks
AbstractPrevious studies have shown an association of sickle cell disease with generalized connective tissue disorders such as pscudoxanthoma elasticum. We recently documented an unexpectedly high prevalence of mitral valve prolapse, a connective tissue disorder, in sickle cell discase. To investigate this association, skin biopsies were analyzed from 32 sickle cel...... hiện toàn bộ
The direct antiglobulin test: A critical step in the evaluation of hemolysisAmerican Journal of Hematology - Tập 87 Số 7 - Trang 707-709 - 2012
Nicole D. Zantek, Scott A. Koepsell, Daryl R. Tharp, Claudia S. Cohn
AbstractThe direct antiglobulin test (DAT) is a laboratory test that detects immunoglobulin and/or complement on the surface of red blood cells. The utility of the DAT is to sort hemolysis into an immune or nonimmune etiology. As with all tests, DAT results must be viewed in light of clinical and other laboratory data. This review highlights the most common clinica...... hiện toàn bộ
Factor VII deficiencyAmerican Journal of Hematology - Tập 10 Số 1 - Trang 79-88 - 1981
Margaret V. Ragni, Jessica H. Lewis, Joel A. Spero, Ute Hasiba
AbstractThis report describes three patients with factor (F) VII deficiency: two adult siblings and an unrelated 5½‐month‐old child who succumbed after several central nervous system (CNS) hemorrhages. This event prompted a review of the literature concerning the incidence and characteristics of intracranial hemorrhage in congenital F VII deficiency.... hiện toàn bộ