American Journal of Hematology
SCIE-ISI SCOPUS (1976-2023)
0361-8609
1096-8652
Mỹ
Cơ quản chủ quản: WILEY , Wiley-Liss Inc.
Lĩnh vực:
Hematology
Các bài báo tiêu biểu
Hematological findings and complications of COVID ‐19Abstract COVID‐19 is a systemic infection with a significant impact on the hematopoietic system and hemostasis. Lymphopenia may be considered as a cardinal laboratory finding, with prognostic potential. Neutrophil/lymphocyte ratio and peak platelet/lymphocyte ratio may also have prognostic value in determining severe cases. During the disease course, longitudinal ev... ...
Tập 95 Số 7 - Trang 834-847 - 2020
An introduction to chimeric antigen receptor (CAR) T‐cell immunotherapy for human cancerChimeric antigen receptor (CAR) T‐cell therapy represents a major advancement in personalized cancer treatment. In this strategy, a patient's own T cells are genetically engineered to express a synthetic receptor that binds a tumor antigen. CAR T cells are then expanded for clinical use and infused back into the patient's body to attack and destroy chemotherapy‐resistant cancer. Dramatic c... ...
Tập 94 Số S1 - 2019
Treatment of sinus histiocytosis with massive lymphadenopathy (rosai‐dorfman disease): Report of a case and literature reviewAbstract Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare disorder of unknown etiology, usually associated with lymph node enlargement in various superficial or deep sites. It usually shows a prolonged clinical course with occasional exacerbation and remission phases. We describe the long‐term follow‐up of a case of SHML that showed typical clinical... ...
Tập 69 Số 1 - Trang 67-71 - 2002
Guidance on the emergent reversal of oral thrombin and factor Xa inhibitorsAbstract The new oral anticoagulants dabigatran, rivaroxaban and apixaban have advantages over warfarin which include no need for laboratory monitoring, less drug–drug interactions and less food‐drug interactions. However, there is no established antidote for patients who are bleeding or require emergent surgery and there is a paucity of evidence to guide the clinic... ...
Tập 87 Số S1 - 2012
Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions
Tập 84 Số 9 - Trang 618-625 - 2009
Estimated annual numbers of US acute‐care hospital patients at risk for venous thromboembolismAbstract Venous thromboembolism (VTE) is a major US health problem. However, the total number of US inpatients who are at risk for VTE is unknown. Our objective was to estimate the number of US acute‐care hospital inpatients who were at risk for VTE according to criteria established by the Seventh American College of Chest Physicians (ACCP) Consensus Conference on A... ...
Tập 82 Số 9 - Trang 777-782 - 2007
Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML The pathophysiology of IDH mutations in tumorigenesis is increasingly described, yet the prognostic significance of IDH1 and IDH2 mutations in AML remains controversial. The primary objective of this study was to define the natural history and prognosis of patients with AML and IDH1 ... ...
Tập 90 Số 8 - Trang 732-736 - 2015
Cryopreservation of hematopoietic stem cellsAbstract Stem cell transplantation represents a critical approach for the treatment of many malignant and non‐malignant diseases. The foundation for these approaches is the ability to cryopreserve marrow cells for future use. This technique is routinely employed in all autologous settings and is critical for cord blood transplantation. A variety of cryopreservatives... ...
Tập 82 Số 6 - Trang 463-472 - 2007
Primary myelofibrosis: 2021 update on diagnosis, risk‐stratification and managementAbstract Disease Overview Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) characterized by stem cell‐derived clonal myeloproliferation that is often but not always accompanied by JAK2 , CALR , or MPL mutations. Additional disease featur...
Tập 96 Số 1 - Trang 145-162 - 2021
Increasing mortality from thrombotic thrombocytopenic purpura in the United States—analysis of national mortality data, 1968–1991Abstract Thrombotic thrombocytopenic purpura (TTP) is a rare disease and the epidemiologic features have been incompletely characterized. Because of the historically high case‐fatality rate for TTP, we analyzed U.S. multiple cause‐of‐death mortality data with TTP listed on the death record for the period 1968–1991, in order to estimate the incidence of TTP, to chara... ...
Tập 50 Số 2 - Trang 84-90 - 1995