Advances in Traditional Medicine

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Spondias mombin: biosafety and GC–MS analysis of anti-viral compounds from crude leaf extracts
Advances in Traditional Medicine - - Trang 1-24 - 2023
Akwasi Boadu, Rajshekhar Karpoormath, Manimbulu Nlooto
Essential oils are combinations of naturally occurring phytochemicals that, alone or in synergy with other compounds, can therapeutically attenuate disease-causing viral infections such as SARS-CoV-2, Ebola, and Marburg viruses. This study aimed to investigate the biosafety of and identification of antiviral phytochemicals of Spondias mombin (Linn) leaf crude extracts by GC–MS analysis. GC–MS anal...... hiện toàn bộ
Unveiling the polypharmacology mechanistic role of steroidal scaffolds from Spondia mombin L. (Anacardiaceae) on EGFR, VEGF, and mTOR: validation of usage in colorectal cancer management in Southwestern Nigeria
Advances in Traditional Medicine - - 2023
Adedokun Oluwasegun, Ume Ogochukwu, Ogunniran Olusewa
Natural products in conjunction with computer-aided drug design have made a significant impact in the development of novel therapeutics in a fast manner in modern-day drug discovery. Spondia mombin has been reported among locals to be effective in the management of colon cancer. Hence, this study was conducted to experimentally justify the anti-tumor properties of Spondia mombin amongst locals usi...... hiện toàn bộ
Synergistic antioxidant activity of plant compositions contained in Chatuphalathika herbal recipe: Terminalia chebula Retz. var. chebula, Terminalia arjuna Wight and Arn., Terminalia bellirica (Gaertn.) Roxb., and Phyllanthus emblica L.
Advances in Traditional Medicine - Tập 22 - Trang 547-556 - 2021
Jirapornchai Suksaeree, Thaniya Wunnakup, Chaowalit Monton
The work sought to investigate, using response surface analysis, the synergistic antioxidant activity among four plants—Terminalia chebula Retz. var. chebula, Terminalia arjuna Wight and Arn., Terminalia bellirica (Gaertn.) Roxb., and Phyllanthus emblica L.—which are comprised in the Chatuphalathika recipe. The response surface analysis of the four-component simplex lattice design was performed us...... hiện toàn bộ
Correction to: Comparative local anaesthetic activity of lignocaine, lignocaine-adrenaline and water extracts of Annona muricata during castration in dogs
Advances in Traditional Medicine - Tập 23 - Trang 947-947 - 2022
Aboh Iku Kisani, Ageh Nonye Immaculate, Saganuwan Alhaji Saganuwan
Evaluation of bromelain and temozolomide synergistic combination in human glioblastoma cells
Advances in Traditional Medicine -
Megha Gautam, Reema Gabrani
Synergistic effect of Cinnamomum zeylanicum and Murraya koenigii formulation for antiobesity and hypolipidemic activity on wistar albino rats
Advances in Traditional Medicine - Tập 21 - Trang 553-563 - 2020
Punet Kumar, Sangam Singh, Md Iftekhar Ahmad
Our research work focussed on to evaluating the synergistic action of ethanolic extract and its formulations (F1 and F2) of Cinnamomum zeylanicum (ECZ) and Murraya koenigii (EMK) for antiobesity and anti-hyperlipidemic activity on the high-fat diet on wistar albino rats. In this research work, rats fed on high-fat diet produced hyperlipidemia (115.00 ± 1.36 mg/dL), which led to an gain in the body...... hiện toàn bộ
The potential of Arum spp. as a cure for hemorrhoids: chemistry, bioactivities, and application
Advances in Traditional Medicine - Tập 20 - Trang 133-141 - 2020
Ekaterina Kozuharova, Zheko Naychov, Vladimir Kochmarov, Niko Benbassat, Marc Gibernau, Georgy Momekov
Hemorrhoids become pathological when swollen or inflamed. They can be very painful and occasionally cause serious anemia as they often break and hardly heal. Orthodox medicine usually treats hemorrhoids through surgery combined with medication containing the flavonoid diosmin. Our previous ethnobotanical and ethnopharmacological research in Bulgaria (Balkan Peninsula) revealed that Arum maculatum ...... hiện toàn bộ
Influence of harvest season and different polarity solvents on biological activities, phenolic compounds and lipid-soluble pigment contents of Spirogyra sp. from Algeria
Advances in Traditional Medicine - Tập 22 - Trang 359-369 - 2021
Larbi Belyagoubi, Nabila Belyagoubi-Benhammou, Fawzia Atik-Bekkara, Djamel Eddine Abdelouahid
Effects of extraction solvent and harvest period on phytochemical analysis and antioxidant and antimicrobial activities of extracts obtained from the freshwater macroalga, Spirogyra sp. were evaluated. The experiment lasted five months, where five crude extracts were obtained by maceration using different solvents: hexane, chloroform, dichloromethane, acetone and methanol. Higher values of yields ...... hiện toàn bộ
Investigative studies on the inhibition of amyloid-like fibrils formation by the extracts of Vernonia amygdalina Del. leaf
Advances in Traditional Medicine - Tập 22 - Trang 163-176 - 2021
Akinwunmi O. Adeoye, Babatunde Joseph Oso
Secondary metabolites from medicinal plants have been reported to inhibit the formation of glucose-induced protein aggregation. This study investigated the inhibitory potential of Vernonia amygdalina leaf extracts on amyloid protein aggregation. Prevention of glycation-induced amyloid-beta fibril formation was evaluated through the assessment of anti-glycation capacities of the extracts, inhibitio...... hiện toàn bộ
Epigallocatechin gallate attenuates neurocognitive impairment in CRISPR-CAS9-induced knockout of DYRK1A gene in zebrafish model
Advances in Traditional Medicine - - Trang 1-15 - 2023
S. Ankul Singh, Gaurav Kumar Bhargav, Swathi Suresh, Chitra Vellapandian
Down Syndrome (DS) is the most widespread genetic disorder and a leading cause of mental retardation. It is assumed that the difference in DYRK1A gene expression with Trisomy 21 significantly contributes to several DS traits, including craniofacial or neurological malformation/deformity. Preparation of Epigallocatechin Gallate (EGCG) enriched fraction of Camellia sinensis and identification of com...... hiện toàn bộ
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