Advances in Traditional Medicine
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The ethanol extract of avocado [Persea americana Mill. (Lauraceae)] seeds reduced the hyperplastic effect of tamoxifen on uterine endometrium without changing its effect on the mammary gland
Advances in Traditional Medicine - Tập 21 - Trang 305-316 - 2020
Tamoxifen is the most common hormonal treatment for estrogen receptor positive
(ER+) breast cancer. However, the long-term use of tamoxifen was associated with
increased risks of endometrial cancer. The literature suggests that combining
tamoxifen with substances endowed with antiproliferative properties could
increase tamoxifen’s chemopreventive benefit. The ethanol extract of Persea
americana Mi...
Pyrrolidine alkaloids and their promises in pharmacotherapy
Advances in Traditional Medicine - Tập 20 - Trang 13-22 - 2020
This review aimed at summarizing the literature pertaining to the biological
activities of pyrrolidine alkaloids and their derivatives obtained from various
sources. For this purpose, an up-to-date search was made in various databases
such as PubMed, Science Direct, Web of Science, Scopus, The American Chemical
Society and Google Scholar. Findings suggest that to date, a number of
pyrrolidine alka...
Spondias mombin: biosafety and GC–MS analysis of anti-viral compounds from crude leaf extracts
Advances in Traditional Medicine - - Trang 1-24 - 2023
Essential oils are combinations of naturally occurring phytochemicals that,
alone or in synergy with other compounds, can therapeutically attenuate
disease-causing viral infections such as SARS-CoV-2, Ebola, and Marburg viruses.
This study aimed to investigate the biosafety of and identification of antiviral
phytochemicals of Spondias mombin (Linn) leaf crude extracts by GC–MS analysis.
GC–MS anal...
Effectiveness of hyper and hypothermic application revulsively on range of motion, symptom score and quality of life in patients with cervical spondylosis: a randomized controlled trial
Advances in Traditional Medicine - - Trang 1-7 - 2022
Cervical spondylosis (CS) is a degenerative age-related disorder affecting the
cervical region of the spinal cord which manifests mainly with radiating pain in
the neck, numbness in fingers, and headache. To control the symptoms and manage
the disease progression, a combination of Complementary and Alternative Medicine
with conventional management is necessary. Hence this study is aimed to evaluat...
Modulatory effect of Justicia secunda leaf extract on hematological status, lipid profile, liver function and oxidative stress in Wistar rats
Advances in Traditional Medicine - - Trang 1-10 - 2023
Justicia secunda is a therapeutic plant with acclaimed beneficial health effects
including blood-boosting potential. However, scientific evidence from in vivo
analyses to buttress such claims have not been exhaustively provided. Herein, we
investigated the effect of J. secunda leaf extract on organs, hematology, lipid
profile and endogenous antioxidant activity in male rats grouped into seven
grou...
Biosurfactants as potential and sustainable substitutes for synthetic drugs against antimicrobial resistance and drug adverse effects: a review
Advances in Traditional Medicine - - Trang 1-13 - 2024
In modern medicine, one major advancement recorded is the discovery of
antibiotics. For the past decades now, the use and misuse of antibiotics have
led most clinically important pathogens to develop multiple drug resistance;
thus, reducing the applications of these antibiotics. The challenges associated
with multi-drug resistance require various strategies such as genomics and
nanotechnology appr...
Unveiling the polypharmacology mechanistic role of steroidal scaffolds from Spondia mombin L. (Anacardiaceae) on EGFR, VEGF, and mTOR: validation of usage in colorectal cancer management in Southwestern Nigeria
Advances in Traditional Medicine - - 2023
Natural products in conjunction with computer-aided drug design have made a
significant impact in the development of novel therapeutics in a fast manner in
modern-day drug discovery. Spondia mombin has been reported among locals to be
effective in the management of colon cancer. Hence, this study was conducted to
experimentally justify the anti-tumor properties of Spondia mombin amongst
locals usi...
Synergistic antioxidant activity of plant compositions contained in Chatuphalathika herbal recipe: Terminalia chebula Retz. var. chebula, Terminalia arjuna Wight and Arn., Terminalia bellirica (Gaertn.) Roxb., and Phyllanthus emblica L.
Advances in Traditional Medicine - Tập 22 - Trang 547-556 - 2021
The work sought to investigate, using response surface analysis, the synergistic
antioxidant activity among four plants—Terminalia chebula Retz. var. chebula,
Terminalia arjuna Wight and Arn., Terminalia bellirica (Gaertn.) Roxb., and
Phyllanthus emblica L.—which are comprised in the Chatuphalathika recipe. The
response surface analysis of the four-component simplex lattice design was
performed us...
Potential nephroprotective effects of resveratrol in drug induced nephrotoxicity: a narrative review of safety and efficacy data
Advances in Traditional Medicine - Tập 20 - Trang 529-544 - 2020
Drug induced nephrotoxicity commonly occurs in hospitalized patients and
sometimes may complicate treatment outcome, especially in critically ill
patients. No universal prophylactic agent is available yet to protect against
drug related nephrotoxicity. Many modalities have been applied with different
successes. Polyphenolic compounds such as resveratrol have been used both
in-vitro and in vivo to ...
Fabrication and evaluation of bamboo fabric coated with extracts of Curcuma longa, Centella asiatica and Azadirachta indica as a wound dressing material
Advances in Traditional Medicine - Tập 21 - Trang 83-95 - 2020
Biomaterials are used on wounds as a dressing material to prevent the infection
and to heal the wounds. In this present study, pure bamboo fabric has been
selected for construction of functional part of bandage, coated with natural
herbs such as Azadirachta indica, Centella asiatica, and Curcuma longa by
microcapsules and exhaustion method. The binding of extracts to the fabric was
confirmed throu...
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