Advanced Pharmaceutical Bulletin

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Bioemulsifiers Derived from Microorganisms: Applications in the Drug and Food Industry
Advanced Pharmaceutical Bulletin - Tập 8 Số 2 - Trang 191-199
Mahmood Alizadeh Sani, Hamed Hamishehkar, Arezou Khezerlou, Maryam Azizi‐Lalabadi, Yaghob Azadi, Elyas Nattagh‐Eshtivani, Mehdi Fasihi, Abed Ghavami, Aydin Aynehchi, Ali Ehsani
Venlafaxine-Induced Cytotoxicity Towards Isolated Rat Hepatocytes Involves Oxidative Stress and Mitochondrial/Lysosomal Dysfunction
Advanced Pharmaceutical Bulletin - Tập 6 Số 4 - Trang 521-530
Elham Ahmadian, Hossein Babaei, Alireza Mohajjel Nayebi, Aziz Eftekhari, Mohammad Ali Eghbal
Mesenchymal Stem Cell-Derived Exosomes: New Opportunity in Cell-Free Therapy
Advanced Pharmaceutical Bulletin - Tập 6 Số 3 - Trang 293-299
Davod Pashoutan Sarvar, Karim Shamsasenjan, Parvin Akbarzadehlaleh
Adenovirus-Mediated Over-Expression of Nrf2 Within Mesenchymal Stem Cells (MSCs) Protected Rats Against Acute Kidney Injury
Advanced Pharmaceutical Bulletin - Tập 5 Số 2 - Trang 201-208
Mohammad Mohammadzadeh-Vardin, Mehryar Habibi Roudkenar, Ali Jahanian‐Najafabadi
Immunomodulatory Activities of Sambucus javanica Extracts in DMBAExposedBALB/c Mouse
Advanced Pharmaceutical Bulletin - Tập 9 Số 4 - Trang 619-623
Wira Eka Putra, Muhaimin Rifa’i
Purpose: Accumulating evidence shows the genus of Sambucus exerts a broad spectrum ofmedicinal potencies such as anticancer, antiviral, antibacterial, and antidiabetes. Based on theprevious studies, we hypothesized that bioactive compounds of Sambucus might alter severalbiological systems, including the immune system. Therefore, this study extensively aimed toevaluate the immunomodulatory activiti... hiện toàn bộ
Successful Application of Alpha Lipoic Acid Niosomal Formulation in Cerebral Ischemic Reperfusion Injury in Rat Model
Advanced Pharmaceutical Bulletin - Tập 12 Số 3 - Trang 541-549 - 2022
Mohammad Amin Raeisi Estabragh, Abbas Pardakhty, Saeid Ahmadzadeh, Shahriar Dabiri, Hamid Reza Mollaei, Mohammad Mehdi Oloumi
Purpose: Free radicals such as hydroxyl and peroxide are contributing factors to neuronaldestruction in cerebral ischemia. Alpha-lipoic acid (ALA) is one of the potent knownantioxidants. Preparation of ALA niosomes allows IV injection and can increase bioavailabilityand penetration into the central nervous system (CNS).Methods: Film hydration method was used to prepare different niosomes composed ... hiện toàn bộ
miR‐146a‐5p and miR-193a-5p Synergistically Inhibited the Proliferation of Human Colorectal Cancer Cells (HT-29 cell line) through ERK Signaling Pathway
Advanced Pharmaceutical Bulletin - Tập 11 Số 4 - Trang 755-764 - 2020
Saeed Noorolyai, Elham Baghbani, Dariush Shanehbandi, Vahid Khaze, Amir Baghbanzadeh, Behzad Mansoori, Khalil Hajiasgharzadeh, Ahad Mokhtarzadeh, Behzad Baradaran
Purpose: The expression of miR-146a-5p and miR-193a-5p in colorectal cancer (CRC) is associated with cancer development, metastasis, and reduced survival rate of the tumor-suffered subjects. This examination aimed to assess the impact of these microRNAs (miRNAs) in CRC and their mechanisms in the proliferation and migration of cancer cells. Methods: miR-146a-5p and -193a-5p were transfected into t... hiện toàn bộ
Application of Various Types of Liposomes in Drug Delivery Systems
Advanced Pharmaceutical Bulletin - Tập 7 Số 1 - Trang 3-9
Mehran Alavi, Naser Karimi, Mohsen Safaei
Using Ketamine and Propofol for Procedural Sedation of Adults in the Emergency Department: A Systematic Review and Meta-Analysis
Advanced Pharmaceutical Bulletin - Tập 9 Số 1 - Trang 5-11
Morteza Ghojazadeh, Sarvin Sanaie, Seyed Pouya Paknezhad, Sahba-Sadat Faghih, Hassan Soleimanpour
Purpose: Ketamine-propofol combination (ketofol) is being used to provide a safe and effective procedural sedation (PS) in emergency department (ED) and may theoretically have beneficial effects since using lower doses of each drug may result in a reduction of the adverse events of both agents while maintaining optimal conditions for performing procedures. This systematic review was conducted to e... hiện toàn bộ
Current Advances in Chitosan Nanoparticles Based Drug Delivery and Targeting
Advanced Pharmaceutical Bulletin - Tập 9 Số 2 - Trang 195-204
Unnati Garg, Swati Chauhan, Upendra Nagaich, Neha Jain
Nanoparticles (NPs) have been found to be potential targeted and controlled release drug delivery systems. Various drugs can be loaded in the NPs to achieve targeted delivery. Chitosan NPs being biodegradable, biocompatible, less toxic and easy to prepare, are an effective and potential tool for drug delivery. Chitosan is natural biopolymer which can be easily functionalized to obtain the desired ... hiện toàn bộ
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