AAPS PharmSciTech

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Drying Using Supercritical Fluid Technology as a Potential Method for Preparation of Chitosan Aerogel Microparticles
AAPS PharmSciTech - Tập 16 - Trang 1235-1244 - 2015
Rana M. Obaidat, Bassam M. Tashtoush, Mohammad F. Bayan, Rana T. Al Bustami, Mohammad Alnaief
Supercritical fluid technology offers several advantages in preparation of microparticles. These include uniformity in particle size, morphology, and drug distribution without degradation of the product. One of the recent advantages is preparation of porous aerogel carrier with proper aerodynamic properties. In this study, we aimed to prepare chitosan aerogel microparticles using supercritical flu...... hiện toàn bộ
Assessment of Tribo-charging and Continuous Feeding Performance of Direct Compression Grades of Isomalt and Mannitol Powders
AAPS PharmSciTech - Tập 24 - Trang 1-12 - 2023
Michela Beretta, Julia Kruisz, Theresa R. Hörmann-Kincses, Viktoria Magosi, Meishan Guo, Majid Naderi, Sarah Heupl, Johann Kastner, Martin Spoerk, Amrit Paudel
Tribo-charging is often a root cause of mass flow deviations and powder adhesion during continuous feeding. Thus, it may critically impact product quality. In this study, we characterized the volumetric (split- and pre-blend) feeding behavior and process-induced charge of two direct compression grades of polyols, galenIQ™ 721 (G721) for isomalt and PEARLITOL® 200SD (P200SD) for mannitol, under dif...... hiện toàn bộ
Potential of Non-aqueous Microemulsions to Improve the Delivery of Lipophilic Drugs to the Skin
AAPS PharmSciTech - Tập 18 - Trang 1739-1749 - 2016
Vanessa F. Carvalho, Debora P. de Lemos, Camila S. Vieira, Amanda Migotto, Luciana B. Lopes
In this study, non-aqueous microemulsions were developed because of the challenges associated with finding pharmaceutically acceptable solvents for topical delivery of drugs sparingly soluble in water. The formulation irritation potential and ability to modulate the penetration of lipophilic compounds (progesterone, α-tocopherol, and lycopene) of interest for topical treatment/prevention of skin d...... hiện toàn bộ
Melt-in-Mouth Multi-particulate System for the Treatment of ADHD: A Convenient Platform for Pediatric Use
AAPS PharmSciTech - Tập 17 - Trang 878-890 - 2015
Jalashri Patadia, Rahul Tripathi, Amita Joshi
Generally, pellets obtained from extrusion/spheronization, containing microcrystalline cellulose (MCC), do not disintegrate. An attempt has been made to develop melt-in-mouth pellets of taste-masked atomoxetine hydrochloride, using extrusion-spheronization, for pediatric patients. Melt-in-mouth pellets were prepared using extrusion-spheronization method and optimized using 33 FFD. MCC (X1, %), man...... hiện toàn bộ
ApoE3 Anchored Liposomal Delivery of Rivastigmine for Brain Delivery: Formulation, Characterization, and In Vivo Pharmacokinetic Evaluation
AAPS PharmSciTech - Tập 24 Số 8
Pooja Khairnar, Ajit Singh, Kailash Ahirwar, Rahul Shukla
A preliminary pharmacokinetic study of liposomal leuprolide dry powder inhaler: A technical note
AAPS PharmSciTech - Tập 6 - Trang E482-E486 - 2005
Aliasgar Shahiwala, Ambikanandan Misra
The developed liposomal DPI of LEU (LLEUn-DPI) demonstrated approximately 50% bioavailability compared with SC route. The studies justify the role of the pulmonary route as a promising alternative to the presently available SC route. The components of liposomal vesicles may be suitably changed to achieve higher bioavailability. Pulmonary delivery of LEU is expected to help in improving patient com...... hiện toàn bộ
Stability Enhancement of Drug Layered Pellets in a Fixed Dose Combination Tablet
AAPS PharmSciTech - - 2013
Matthew D. Burke, Xiaorong He, Chris C. Cook, Greg A. Petrov, Susan Long, Mark D. Coffin
Anti-solvent Precipitation Method Coupled Electrospinning Process to Produce Poorly Water-Soluble Drug-Loaded Orodispersible Films
AAPS PharmSciTech - - 2019
Qingchun Song, Xiong Guo, Yi Sun, Mingshi Yang
Vacuum foam drying for preservation of LaSota virus: Effect of additives
AAPS PharmSciTech - Tập 7 - Trang E30-E37 - 2017
Sambhaji Pisal, Gopal Wawde, Shailendra Salvankar, Sanjay Lade, Shivajirao Kadam
The purpose of this research was to apply vacuum foam drying (VFD) for processing of LaSota virus and to screen formulation additives for its stability. The aqueous dispersion of harvest containing sucrose or trehalose in combination with additive (monosaccharides, polymers, N-Z-amine) was prepared. The diluted dispersions in vials were vacuum concentrated, foamed to form a continuous structure, a...... hiện toàn bộ
Impact of Properties of Hydrated Silicon Dioxide as Core Material on the Characteristics of Drug-containing Particles Prepared by the 2-step Process Melt Granulation Technology, MALCORE®
AAPS PharmSciTech - Tập 24 Số 1
Ryota Kimata, Naoki Yoshihara, Takayuki Terukina, Takanori Kanazawa, Hiromu Kondo
Tổng số: 2,894   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10