Wound dehiscence and stump infection after lower limb amputation: risk factors and association with antibiotic use

Karakoç, 2004, Change in amputation rate in a Turkish diabetic foot population, J Diabetes Complicat., 18, 169, 10.1016/j.jdiacomp.2003.09.004 Assal, 2001, Patient education in Switzerland: from diabetes to chronic diseases, Patient Educ Couns., 44, 65, 10.1016/S0738-3991(01)00105-7 Stone, 2006, Factors affecting perioperative mortality and wound-related complications following major lower extremity amputations, Ann Vasc Surg., 20, 209, 10.1007/s10016-006-9009-z Pollard, 2006, Mortality and morbidity after transmetatarsal amputation: retrospective review of 101 cases, J Foot Ankle Surg., 45, 91, 10.1053/j.jfas.2005.12.011 Carmona, 2007, Walking activity in prosthesis-bearing lower-limb amputees, Rev Chir Orthop Reparatrice Appar Mot., 93, 109, 10.1016/S0035-1040(07)90213-5 Krause, 2009, Outcome of transmetatarsal amputations in diabetics using antibiotic beads, Foot Ankle Int., 30, 486, 10.3113/FAI.2009.0486 de Godoy, 2010, Hospital infection after major amputations, Ann Clin Microbiol Antimicrob., 9, 15, 10.1186/1476-0711-9-15 Sadat, 2008, Five day antibiotic prophylaxis for major lower limb amputation reduces wound infection rates and the length of in-hospital stay, Eur J Vasc Endovasc Surg., 35, 75, 10.1016/j.ejvs.2007.07.016 Uçkay, 2010, Preventing surgical site infections, Expert Rev Anti Infect Ther., 8, 657, 10.1586/eri.10.41 McIntosh, 2009, Antibiotic prophylaxis for the prevention of infection after major limb amputation, Eur J Vasc Endovasc Surg., 37, 696, 10.1016/j.ejvs.2009.01.013 Uçkay, 2009, Activity and impact on antibiotic use and costs of a dedicated infectious diseases consultant on a septic orthopaedic unit, J Infect., 58, 205, 10.1016/j.jinf.2009.01.012 Norgren, 2007, Inter-Society consensus for the management of peripheral arterial disease (TASC II), Eur J Vasc Endovasc Surg., 33, 1, 10.1016/j.ejvs.2006.09.024 Berendt, 2006, Counterpoint: hyperbaric oxygen for diabetic foot wounds is not effective, Clin Infect Dis., 43, 193, 10.1086/505223 Owens, 1978, ASA physical status classifications: a study of consistency of ratings, Anesthesiology., 49, 239, 10.1097/00000542-197810000-00003 Charlson, 1987, A new method of classifying prognostic comorbidity in longitudinal studies: development and validation, J Chronic Dis., 40, 373, 10.1016/0021-9681(87)90171-8 Vittinghoff, 2007, Relaxing the rule of ten events per variable in logistic and Cox regression, Am J Epidemiol., 165, 710, 10.1093/aje/kwk052 Mueller, 1995, Incidence of skin breakdown and higher amputation after transmetatarsal amputation: implications for rehabilitation, Arch Phys Med Rehabil., 76, 50, 10.1016/S0003-9993(95)80042-5 Tracy, 1982, Management of ischemia of the foot beyond arterial reconstruction, Surg Gynecol Obstet., 155, 377 Akinci, 2010, The effect of creatinine clearance on the short-term outcome of neuropathic diabetic foot ulcers, Primary Care Diabetes., 4, 181, 10.1016/j.pcd.2010.04.006 Adera, 1995, Prediction of amputation wound healing with skin perfusion pressure, J Vasc Surg., 21, 823, 10.1016/S0741-5214(05)80014-X Wutschert, 1997, Determination of amputation level in ischemic limbs. Reappraisal of the measurement of TcPo2, Diabetes Care., 20, 1315, 10.2337/diacare.20.8.1315 Bunt, 1996, TcPO2 as an accurate predictor of therapy in limb salvage, Ann Vasc Surg., 10, 224, 10.1007/BF02001886 Harbarth, 2000, Prolonged antibiotic prophylaxis after cardiovascular surgery and its effect on surgical site infections and antimicrobial resistance, Circulation., 101, 2916, 10.1161/01.CIR.101.25.2916