Vitamin-Dependent Methionine Metabolism and Alcoholic Liver Disease

Advances in Nutrition - Tập 2 - Trang 421-427 - 2011
Charles H. Halsted1, Valentina Medici1
1Department of Internal Medicine, Genome and Biomedical Research Facility, University of California, Davis, CA

Tài liệu tham khảo

Mann, 2003, The epidemiology of alcoholic liver disease, Alcohol Res Health, 27, 209 McCullough, 1998, Gender-dependent alterations in serum leptin in alcoholic cirrhosis, Gastroenterology, 115, 947, 10.1016/S0016-5085(98)70267-7 Tilg, 2000, Mechanisms of disease: cytokines in alcoholic and nonalcoholic steatohepatitis, N Engl J Med, 343, 1467, 10.1056/NEJM200011163432007 Cederbaum, 2010, Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury, World J Gastroenterol, 16, 1366, 10.3748/wjg.v16.i11.1366 You, 2004, Recent advances in alcoholic liver disease II. Minireview: molecular mechanisms of alcoholic fatty liver, Am J Physiol Gastrointest Liver Physiol, 287, G1, 10.1152/ajpgi.00056.2004 Dara, 2011, The contribution of endoplasmic reticulum stress to liver diseases, Hepatology, 53, 1752, 10.1002/hep.24279 Crabb, 2004, Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha, Alcohol, 34, 35, 10.1016/j.alcohol.2004.07.005 Purushotham, 2009, Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation, Cell Metab, 9, 327, 10.1016/j.cmet.2009.02.006 You, 2004, The role of AMP-activated protein kinase in the action of ethanol in the liver, Gastroenterology, 127, 1798, 10.1053/j.gastro.2004.09.049 Vance, 2004, Phospholipid biosynthesis in mammalian cells, Biochem Cell Biol, 82, 113, 10.1139/o03-073 Noga, 2002, An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins, J Biol Chem, 277, 42358, 10.1074/jbc.M204542200 Paik, 2011, The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice, Hepatology, 53, 1730, 10.1002/hep.24281 Halsted, 2004, Nutrition and alcoholic liver disease, Semin Liver Dis, 24, 289, 10.1055/s-2004-832941 Lumeng, 1978, The role of acetaldehyde in mediating the deleterious effect of ethanol on pyridoxal 5′-phosphate metabolism, J Clin Invest, 62, 286, 10.1172/JCI109128 Herbert, 1963, Correlation of folate deficiency with alcoholism and associated macrocytosis, anemia, and liver disease, Ann Intern Med, 58, 977, 10.7326/0003-4819-58-6-977 Halsted, 1971, Decreased jejunal uptake of labeled folic acid (3 H-PGA) in alcoholic patients: roles of alcohol and nutrition, N Engl J Med, 285, 701, 10.1056/NEJM197109232851301 Tamura, 1981, Hepatic folate metabolism in the chronic alcoholic monkey, J Lab Clin Med, 97, 654 McMartin, 1989, Effects of chronic ethanol and diet treatment on urinary folate excretion and development of folate deficiency in the rat, J Nutr, 119, 1490, 10.1093/jn/119.10.1490 Tamura, 1983, Folate turnover in chronically alcoholic monkeys, J Lab Clin Med, 101, 623 Kanazawa, 1985, Total corrinoid, cobalamin (vitamin B-12), and cobalamin analogue levels may be normal in serum despite cobalamin in liver depletion in patients with alcoholism, Lab Invest, 53, 108 Kharbanda, 2009, Alcoholic liver disease and methionine metabolism, Semin Liver Dis, 29, 155, 10.1055/s-0029-1214371 Mato, 1994, S-adenosylmethionine and the liver, 461 Mato, 2002, S-adenosylmethionine: a control switch that regulates liver function, FASEB J, 16, 15, 10.1096/fj.01-0401rev Clarke, 2001, S-adenosylmethionine-dependent methyltransferases, 63 Finkelstein, 1975, Activation of cystathionine synthase by adenosylmethionine and adenosylethionine, Biochem Biophys Res Commun, 66, 81, 10.1016/S0006-291X(75)80297-X Prudova, 2006, S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity, Proc Natl Acad Sci USA, 103, 6489, 10.1073/pnas.0509531103 Lee, 2004, Abnormal hepatic methionine and glutathione metabolism in patients with alcoholic hepatitis, Alcohol Clin Exp Res, 28, 173, 10.1097/01.ALC.0000108654.77178.03 Villanueva, 2004, Hepatic transmethylation reactions in micropigs with alcoholic liver disease, Hepatology, 39, 1303, 10.1002/hep.20168 Barak, 1987, Effects of prolonged ethanol feeding on methionine metabolism in rat liver, Biochem Cell Biol, 65, 230, 10.1139/o87-029 Ruiz, 1998, Nitric oxide inactivates rat hepatic methionine adenosyltransferase In vivo by S-nitrosylation, Hepatology, 28, 1051, 10.1002/hep.510280420 Sánchez-Góngora, 1997, Interaction of liver methionine adenosyltransferase with hydroxyl radical, FASEB J, 11, 1013, 10.1096/fasebj.11.12.9337154 Halsted, 2002, Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig, Proc Natl Acad Sci USA, 99, 10072, 10.1073/pnas.112336399 Lieber, 1990, S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon, Hepatology, 11, 165, 10.1002/hep.1840110203 Zhuge, 2007, Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes, Arch Biochem Biophys, 466, 177, 10.1016/j.abb.2007.06.007 Ji, 2003, Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice, Gastroenterology, 124, 1488, 10.1016/S0016-5085(03)00276-2 Kharbanda, 2007, Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway, J Hepatol, 46, 314, 10.1016/j.jhep.2006.08.024 Kharbanda, 2005, A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes, J Nutr, 135, 519, 10.1093/jn/135.3.519 Kharbanda, 2009, Betaine administration corrects ethanol-induced defective VLDL secretion, Mol Cell Biochem, 327, 75, 10.1007/s11010-009-0044-2 Song, 2004, S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease, Hepatology, 40, 989, 10.1002/hep.20412 Horne, 1997, Transport of S-adenosylmethionine in isolated rat liver mitochondria, Arch Biochem Biophys, 343, 201, 10.1006/abbi.1997.0167 Song, 2007, Alcohol-induced S-adenosylhomocysteine accumulation in the liver sensitizes to TNF hepatotoxicity: possible involvement of mitochondrial S-adenosylmethionine transport, Biochem Pharmacol, 74, 521, 10.1016/j.bcp.2007.05.005 Colell, 1997, Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: effect of membrane physical properties and S-adenosyl-L-methionine, Hepatology, 26, 699 Song, 2003, S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice, J Nutr Biochem, 14, 591, 10.1016/S0955-2863(03)00116-5 Sykora, 2009, S-adenosyl-L-methionine co-administration prevents the ethanol-elicited dissociation of hepatic mitochondrial ribosomes in male rats, Alcohol Clin Exp Res, 33, 1, 10.1111/j.1530-0277.2008.00803.x Bailey, 2006, S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver, Am J Physiol Gastrointest Liver Physiol, 291, G857, 10.1152/ajpgi.00044.2006 Andringa, 2010, Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection, Am J Physiol Gastrointest Liver Physiol, 298, G732, 10.1152/ajpgi.00332.2009 Halsted, 1993, Centrilobular distribution of acetaldehyde and collagen in the ethanol- fed micropig, Hepatology, 18, 954, 10.1002/hep.1840180429 Halsted, 1996, Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation, Hepatology, 23, 497, 10.1002/hep.510230314 Savage, 1986, Anemia in alcoholics, Medicine (Baltimore), 65, 322, 10.1097/00005792-198609000-00005 Esfandiari, 2005, Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs, Am J Physiol Gastrointest Liver Physiol, 289, G54, 10.1152/ajpgi.00542.2004 Esfandiari, 2007, S-adenosylmethionine attenuates hepatic lipid synthesis in micropigs fed ethanol with a folate-deficient diet, Alcohol Clin Exp Res, 31, 1231, 10.1111/j.1530-0277.2007.00407.x Villanueva, 2007, S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet, Alcohol Clin Exp Res, 31, 1934, 10.1111/j.1530-0277.2007.00511.x Shukla, 2008, Emerging role of epigenetics in the actions of alcohol, Alcohol Clin Exp Res, 32, 1525, 10.1111/j.1530-0277.2008.00729.x Watanabe, 1995, Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia, Proc Natl Acad Sci USA, 92, 1585, 10.1073/pnas.92.5.1585 Esfandiari, 2010, Epigenetic regulation of hepatic endoplasmic reticulum stress pathways in the ethanol-fed cystathionine beta synthase-deficient mouse, Hepatology, 51, 932, 10.1002/hep.23382 Cabrero, 1988, Specific loss of the high-molecular-weight form of S-adenosyl-L- methionine synthetase in human liver cirrhosis, Hepatology, 8, 1530, 10.1002/hep.1840080610 Duce, 1988, S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis, Hepatology, 8, 65, 10.1002/hep.1840080113 Look, 2000, Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase?, Scand J Gastroenterol, 35, 866, 10.1080/003655200750023255 Medici, 2010, Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease, J Hepatol, 53, 551, 10.1016/j.jhep.2010.03.029 Baker, 1975, Inability of chronic alcoholics with liver disease to use food as a source of folates, thiamin and vitamin B-6, Am J Clin Nutr, 28, 1377, 10.1093/ajcn/28.12.1377 Glória, 1997, Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption, Am J Gastroenterol, 92, 485 Cravo, 1996, Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B-12, and vitamin B-6 status, Am J Clin Nutr, 63, 220, 10.1093/ajcn/63.2.220 Loguercio, 1994, Effect of S-adenosyl-L-methionine administration on red blood cell cysteine and glutathione levels in alcoholic patients with and without liver disease, Alcohol Alcohol, 29, 597 Vendemiale, 1989, Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease, Scand J Gastroenterol, 24, 407, 10.3109/00365528909093067 Mato, 1999, S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial, J Hepatol, 30, 1081, 10.1016/S0168-8278(99)80263-3 Rambaldi, 2006, S-adenosyl-L-methionine for alcoholic liver diseases, Cochrane Database Syst Rev, 10.1002/14651858.CD002235.pub2 Lieber, 2003, II. Veterans Affairs Cooperative Study of polyenylphosphatidylcholine in alcoholic liver disease, Alcohol Clin Exp Res, 27, 1765, 10.1097/01.ALC.0000093743.03049.80 Aleynik, 2003, Polyenylphosphatidylcholine corrects the alcohol-induced hepatic oxidative stress by restoring s-adenosylmethionine, Alcohol Alcohol, 38, 208, 10.1093/alcalc/agg066 Medici, 2011, S-adenosylmethionine treatment of alcoholic liver disease: a double-blind, randomized, placebo-controlled trial, Alcohol Clin Exp Res, 10.1111/j.1530-0277.2011.01547.x