Vitamin D Supplementation Is Associated with a Reduction in Self-Reported Falls among Older Adults with Previous Fall History — Feasibility Study

SERDI - Tập 11 - Trang 224-230 - 2021
Stephen D. Anton1,2, R. T. Mankowski1, P. Qiu3, L. You4, B. A. Bensadon1, E. J. Audino1, C. Custodero1,5, J. H. Lee6, J. Hincapie1, C. McLaren1, C. Leeuwenburgh1, S. P. Ganesh7,8
1Department of Aging and Geriatric Research, University of Florida, Gainesville, USA
2Department of Clinical and Health Psychology, University of Florida, Gainesville, USA
3Department of Biostatistics, University of Florida, Gainesville, USA
4Health Informatics Institute, University of South Florida, Tampa, USA.
5Dipartimento Interdisciplinare di Medicina, Clinica Medica Cesare Frugoni, University of Bari Aldo Moro, Bari, Italy
6Department of Health Education and Behavior, University of Florida, Gainesville, USA
7Physical Medicine and Rehabilitation Service, North FL/South GA Veterans Health System, Gainesville, USA
8Department of Occupational Therapy, University of Florida, Gainesville, USA

Tóm tắt

Vitamin D insufficiency contributes to muscle weakness and a higher risk of falls in older adults. This study explored the impact of vitamin D supplementation on self-reported falls and physical function in older adults with low vitamin D levels and a recent fall history. Twenty-five older adults ≥ 70 years with two or more falls during the past year, low vitamin D blood levels (≥10 ng/ml and < 30 ng/mL), and slow gait speed (1.2 m/s) participated in a 6-month vitamin D supplementation (800 IU/day) study. A modified version of the Morse Fall Scale questionnaire was used to assess frequency of falls over one-year prior to study enrollment. Functional outcomes (short physical performance battery, handgrip strength, gait Timed Up and Go, and six-minute walk), and vitamin D levels were assessed at baseline and 6-month follow-up. Based on diaries and pill counts, participants were generally adherent to the intervention (6 of 7 days per week). Supplementation with 800 IU/day of vitamin D for 6 months increased blood vitamin D levels from 23.25±4.8 ng/ml to 29.13±6.9 ng/ml (p<0.001). Self-reported number of falls decreased from an average of 3.76 ± 2.2 falls in one-year to 0.76 ± 1.4 falls (p <0.0001) over the 6-month intervention. No changes in functional outcome measures were observed. Vitamin D supplementation at the currently recommended dose of 800 IU/day increased blood vitamin D levels and reduced frequency of falls in older adults with low vitamin D levels and a recent fall history.

Tài liệu tham khảo

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