Unexpected pathogen presenting with purulent meningitis

BMJ Case Reports - Tập 13 Số 3 - Trang e231825 - 2020
Jamie Bering1, Carlos Hartmann2, Kara Asbury2, Holenarasipur R. Vikram2
1Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona, USA
2Division of Infectious Diseases, Mayo Clinic, Phoenix, Arizona, USA

Tóm tắt

Herein we report a case of a 67-year-old man with chronic lymphocytic leukaemia who developed acute onset of fever and altered mental status while receiving ibrutinib therapy. He was eventually found to haveCapnocytophaga canimorsusmeningitis. Timely diagnosis and appropriate antimicrobial therapy was associated with a favourable outcome. We describe challenges associated with appropriate identification of, and briefly review infections caused byCapnocytophagasp. To our knowledge, this is the first case of invasiveC. canimorsusinfection in the setting of ibrutinib therapy, and adds to the growing list of serious infections that have been associated with this agent.

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