Unexpected evidence for active brown adipose tissue in adult humans

Abouzied MM, Crawford ES, Nabi HA.18F-FDG imaging: pitfalls and artifacts.J Nucl Med Technol33: 145–155, 2005.

10.1002/path.1700910126

10.1042/cs0660179

10.1152/ajpendo.1985.248.5.E507

Bar-Shalom R, Gaitini D, Keidar Z, Israel O.Non-malignant FDG uptake in infradiaphragmatic adipose tissue: a new site of physiological tracer biodistribution characterised by PET/CT.Eur J Nucl Med Mol Imaging31: 1105–1113, 2004.

Barrington SF, Maisey MN.Skeletal muscle uptake of fluorine-18-FDG: effect of oral diazepam.J Nucl Med37: 1127–1129, 1996.

10.1007/s00259-006-0244-x

Bonnin F, Lumbroso J, Tenenbaum F, Hartmann O, Parmentier C.Refining interpretation of MIBG scans in children.J Nucl Med35: 803–809, 1994.

10.1007/BF01120989

10.1042/cs0750021

10.1152/physrev.00015.2003

10.1002/jcb.240430306

10.3348/kjr.2006.7.1.57

10.1097/00003072-200205000-00016

10.1210/en.2003-0857

Chiba S, Katsuragi I, Simada T, Adachi I, Satoh Y, Noguchi H, Gotoh K, Tsubone T, Fujiwara K, Masaki T, Kakuma T, Kang M, Tanaka K, Hamaguchi K, Wada C, Yoshimatsu H.Evaluation of human brown adipose tissue using positron emission tomography, computerised tomography and histochemical studies in association with body mass index, visceral fat accumulation and insulin resistance (Abstract).Obes Rev7,Suppl2: 87, 2006.

10.1097/01.rlu.0000204199.33136.05

Cohade C, Mourtzikos KA, Wahl RL.“USA-Fat”: prevalence is related to ambient outdoor temperature-evaluation with 18F-FDG PET/CT.J Nucl Med44: 1267–1270, 2003.

Cohade C, Osman M, Pannu HK, Wahl RL.Uptake in supraclavicular area fat (“USA-Fat”): description on 18F-FDG PET/CT.J Nucl Med44: 170–176, 2003.

10.1042/cs0690343

Dobert N, Menzel C, Hamscho N, Wordehoff W, Kranert WT, Grunwald F.Atypical thoracic and supraclavicular FDG-uptake in patients with Hodgkin's and non-Hodgkin's lymphoma.Q J Nucl Med Mol Imaging48: 33–38, 2004.

10.1097/00003072-199502000-00011

10.1038/387090a0

Engel H, Steinert H, Buck A, Berthold T, Huch Boni RA, von Schulthess GK.Whole body PET: physiological and artifactual fluorodeoxyglucose accumulations.J Nucl Med37: 441–446, 1996.

10.1148/107.2.279

Fueger BJ, Czernin J, Hildebrandt I, Tran C, Halpern BS, Stout D, Phelps ME, Weber WA.Impact of animal handling on the results of 18F-FDG PET studies in mice.J Nucl Med47: 999–1006, 2006.

10.1055/s-2004-830407

10.1007/s11307-005-0030-3

10.1016/j.mibio.2004.08.003

Garruti G, Ricquier D.Analysis of uncoupling protein and its mRNA in adipose tissue deposits of adult humans.Int J Obes16: 383–390, 1992.

Gelfand MJ.123I-MIBG uptake in the neck and shoulders of a neuroblastoma patient: damage to sympathetic innervation blocks uptake in brown adipose tissue.Pediatr Radiol34: 577–579, 2004.

10.1007/s00247-005-1505-8

10.1152/ajpendo.00387.2005

10.1096/fj.00-0536fje

10.1080/08998280.2005.11928089

10.1007/s00259-002-0902-6

10.1111/j.1075-122X.2005.00134.x

10.1007/BF02984575

10.1007/s00125-005-1936-7

10.2337/diabetes.54.5.1385

10.1007/s00259-005-1851-7

10.1177/41.5.8468458

Kyparos D, Arsos G, Georga S, Petridou A, Kyparos A, Papageorgiou E, Mougios V, Matziari C, Karakatsanis C.Assessment of brown adipose tissue activity in rats by 99mTc-sestamibi uptake.Physiol Res55: 653–659, 2006.

Laurberg JM, Olsen AK, Hansen SB, Bottcher M, Morrison M, Ricketts SA, Falk E.Imaging of vulnerable atherosclerotic plaques with FDG-microPET: No FDG accumulation.Atherosclerosis. In press.

10.1079/PNS19890036

Lean ME, James WP.Brown adipose tissue in man. In:Brown Adipose Tissue, edited by Trayhurn P and Nicholls DG. London, UK: Edward Arnold, 1986, p. 339–365.

Lean ME, James WP, Jennings G, Trayhurn P.Brown adipose tissue in patients with pheochromocytoma.Int J Obes10: 219–227, 1986.

10.1042/cs0710291

Lin D, Jacobs M, Percy T, Dowdy Y, Mantil J.High 2-deoxy- 2[F-18]fluoro-D-glucose uptake on positron emission tomography in hibernoma originally thought to be myxoid liposarcoma.Mol Imaging Biol7: 2001–2002, 2005.

10.1038/35007527

10.1038/366740a0

Lumbroso J, Glammarile F, Hartmann O, Bonnin F, Parmentier C.Upper clavicular and cardiac meta-[123]iodobenzylguanidine uptake in children.Q J Nucl Med39: 17–20, 1995.

10.1152/ajpcell.1989.257.4.C714

10.1042/bj2770119

10.1074/jbc.M000547200

10.1097/01.rlu.0000102761.90104.c6

10.1016/j.bcp.2004.03.028

Okuyama C, Sakane N, Yoshida T, Shima K, Kurosawa H, Kumamoto K, Ushijima Y, Nishimura T.(123)I- or (125)I-metaiodobenzylguanidine visualization of brown adipose tissue.J Nucl Med43: 1234–1240, 2002.

10.1016/S0003-4266(06)72534-3

10.1097/01.rlu.0000156798.59230.2e

10.1210/jcem-54-4-803

10.1007/s00259-006-0066-x

Soderlund V, Larsson SA, Jacobsson H.Reduction of FGD uptake in brown adipose tissue in clinical patients by a single dose of propranolol.Eur J Nucl Med Mol Imaging. In press.

10.1097/00006231-200411000-00007

Tatsumi M, Engles JM, Ishimori T, Nicely O, Cohade C, Wahl RL.Intense (18)F-FDG uptake in brown fat can be reduced pharmacologically.J Nucl Med45: 1189–1193, 2004.

10.1097/01.rct.0000159510.13694.8c

10.2214/ajr.183.4.1831127

10.1097/00004728-200603000-00033

Weber WA.Brown adipose tissue and nuclear medicine imaging.J Nucl Med45: 1101–1103, 2004.

Yeung HW, Grewal RK, Gonen M, Schoder H, Larson SM.Patterns of (18)F-FDG uptake in adipose tissue and muscle: a potential source of false-positives for PET.J Nucl Med44: 1789–1796, 2003.