Understanding the clinical profile of patients with frozen shoulder: a longitudinal multicentre observational study

BMJ Open - Tập 12 Số 11 - Trang e056563 - 2022
Michel GCAM Mertens1,2, Mira Meeus3,1,2, Suzie Noten4,5, Olivier Verborgt6,7,2, Erik Fransén8, Enrique Lluch Girbés9,1,10, Marta Aguilar Rodríguez10, Santiago Navarro-Ledesma11, Manuel Fernández-Sánchez12, Alejandro Luque-Suárez13, Filip Struyf14, Lirios Dueñas10
1Pain in Motion International Research Group, www.paininmotion.be, Belgium
2Research Group MOVANT, Department of Rehabilitation Sciences and Physiotherapy (REVAKI), University of Antwerp Faculty of Medicine and Health Sciences, Wilrijk, Belgium
3Department of Rehabilitation Sciences and Physiotherapy, Ghent University, Ghent, Belgium
4Department of Rehabilitation Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands
5Rijndam Rehabilitation, Rotterdam, The Netherlands
6Department of Orthopedic Surgery and Traumatology, AZ Monica, Antwerpen, Belgium
7Department of Orthopedic Surgery, University Hospital Antwerp, Edegem, Belgium
8StatUa Center for Statistics, University of Antwerp, Antwerpen, Belgium
9Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Vrije Universiteit Brussel, Brussels, Belgium
10Physiotherapy in Motion, Multi-Specialty Research Group (PTinMOTION), Department of Physical Therapy, University of Valencia, Valencia, Spain
11Department of Physiotherapy, University of Granada, Melilla, Spain
12Department of Nursing, Physiotherapy and Medicine, University of Almeria, Almeria, Spain
13Department of Physiotherapy, University of Malaga, Malaga, Spain
14Rehabilitation Sciences, Universiteit Antwerpen Campus Drie Eiken, Wilrijk, Belgium

Tóm tắt

IntroductionThere is a large diversity in the clinical presentation of frozen shoulder (FS) and the clinical outcome is not always satisfactory. The aim of the current study was to examine to what extent range of motion (ROM) limitation, metabolic factors (diabetes mellitus and thyroid disorders), autonomic symptoms and pain sensitivity may contribute to the prognosis in terms of shoulder pain and disability and quality of life in patients with FS.MethodsPatients with stage 1 or 2 FS were longitudinally followed-up during 9 months after baseline assessment. They completed six questionnaires and underwent quantitative sensory testing (pressure pain thresholds, temporal summation and conditioned pain modulation) and ROM assessment.ResultsOne hundred and forty-nine patients with FS were initially recruited and 121 completed at least one follow-up measurement. Shoulder pain and disability improved over time and diabetes mellitus was found to be a prognostic factor for final outcome. Several domains of quality of life also improved over time and external rotation ROM, diabetes mellitus, thyroid disorder and autonomic symptoms were found to be prognostic factors for final outcome. These prognostic factors explained 2.5%–6.3% of the final outcome of shoulder pain and disability and quality of life.Discussion and conclusionIn patients with FS, prognostic variables were able to predict different outcomes, indicating that outcomes in this population can be variable-dependent. Other variables not explored in this study might contribute to the prognosis of patients with FS, which should be investigated in future research. In clinical practice, baseline assessment of prognostic factors and focusing on a more holistic approach might be useful to inform healthcare practitioners about progression of patients with FS during a 9-month period.

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