Twist Overexpression Induces In vivo Angiogenesis and Correlates with Chromosomal Instability in Breast Cancer

Lochter A. Plasticity of mammary epithelia during normal development and neoplastic progression. Biochem Cell Biol 1998; 76: 997–1008.

Woodhouse EC, Chuaqui RF, Liotta LA. General mechanisms of metastasis. Cancer 199715; 80: 1529–37.

Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57–70.

Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002; 2: 563–72.

Thiery JP. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 2003; 15: 740–6.

Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2: 442–54.

Hay ED. An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) 1995; 154: 8–20.

Kang Y, Massague J. Epithelial-mesenchymal transitions: Twist in development and metastasis. Cell 2004; 118: 277–9.

Castanon I, Baylies MK. A Twist in fate: evolutionary comparison of Twist structure and function. Gene 2002; 287: 11–22.

el Ghouzzi V, Le Merrer M, Perrin-Schmitt F, et al. Mutations of the TWIST gene in the Saethre-Chotzen syndrome. Nat Genet 1997; 15: 42–6.

El Ghouzzi V, Legeai-Mallet L, Aresta S, et al. Saethre-Chotzen mutations cause TWIST protein degradation or impaired nuclear location. Hum Mol Genet 2000; 9: 813–9.

El Ghouzzi V, Legeai-Mallet L, Benoist-Lasselin C, et al. Mutations in the basic domain and the loop-helix II junction of TWIST abolish DNA binding in Saethre-Chotzen syndrome. FEBS Lett 2001; 492: 112–8.

Yousfi M, Lasmoles F, El Ghouzzi V, Marie PJ. Twist haploinsufficiency in Saethre-Chotzen syndrome induces calvarial osteoblast apoptosis due to increased TNFα expression and caspase-2 activation. Hum Mol Genet 2002; 11: 359–69.

Maestro R, Dei Tos AP, Hamamori Y, et al. Twist is a potential oncogene that inhibits apoptosis. Genes Dev 1999; 13: 2207–17.

Wang X, Ling MT, Guan XY, et al. Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells. Oncogene 2004; 23: 474–82.

Rosivatz E, Becker I, Specht K, et al. Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer. Am J Pathol 2002; 161: 1881–91.

Yang J, Mani SA, Donaher JL, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004; 117: 927–39.

Stasinopoulos IA, Mironchik Y, Raman A, et al. HOXA5-twist interaction alters p53 homeostasis in breast cancer cells. J Biol Chem 2005; 280: 2294–9.

Bhujwalla ZM, Artemov D, Natarajan K, Solaiyappan M, Kollars P, Kristjansen PE. Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470. Clin Cancer Res 2003; 9: 355–62.

Burger H, Poremba C, Diallo R, Dockhorn-Dworniczak B, Bocker W. Establishing a cytogenetic and morphological progression models of invasive breast cancer. Comparative genomic hybridization (CGH) in malignant and premalignant tumors of the female breast. Pathologe 2000; 21: 375–82.

Thisse B, el Messal M, Perrin-Schmitt F. The twist gene: isolation of a Drosophila zygotic gene necessary for the establishment of dorsoventral pattern. Nucleic Acids Res 1987; 15: 3439–53.

Baylies MK, Bate M. Twist: a myogenic switch in Drosophila. Science 1996; 272: 1481–4.

O'Rourke MP, Tam PP. Twist functions in mouse development. Int J Dev Biol 2002; 46: 401–13.

Technau U, Scholz CB. Origin and evolution of endoderm and mesoderm. Int J Dev Biol 2003; 47: 531–9.

Wodarz A. Establishing cell polarity in development. Nat Cell Biol 2002; 4: E39–44.

Hendrix MJ, Seftor EA, Seftor RE, Trevor KT. Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior. Am J Pathol 1997; 150: 483–95.

Vincent-Salomon A, Thiery JP. Host microenvironment in breast cancer development: epithelial-mesenchymal transition in breast cancer development. Breast Cancer Res 2003; 5: 101–6.

Grunert S, Jechlinger M, Beug H. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat Rev Mol Cell Biol 2003; 4: 657–65.

Boyer B, Valles AM, Edme N. Induction and regulation of epithelial-mesenchymal transitions. Biochem Pharmacol 2000; 60: 1091–9.

Boyer B, Thiery JP. Epithelium-mesenchyme interconversion as example of epithelial plasticity. Acta Pathol Microbiol Immunol Scand 1993; 101: 257–68.

Cano A, Perez-Moreno MA, Rodrigo I, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000; 2: 76–83.

Leptin M. Twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes Dev 1991; 5: 1568–76.

Horsman MR, Overgaard J. The oxygen effect and the tumour microenvironment. In: Steel GG, editor. Basic clinical radiobiology for radiation oncologists. 3rd ed. London: Edward Arnold; 2002. p. 158–68.

Bikfalvi A, Bicknell R. Recent advances in angiogenesis, anti-angiogenesis and vascular targeting. Trends Pharmacol Sci 2002; 23: 576–82.

Cavallaro U, Christofori G. Molecular mechanisms of tumor angiogenesis and tumor progression. J Neurooncol 2000; 50: 63–70.

Tse GMK, Lui PCW, Lee CS, et al. Stromal expression of vascular endothelial growth factor correlates with tumor grade and microvessel density in mammary phyllodes tumors: a multicenter study of 185 cases. Hum Pathol 2004; 35: 1053–7.

Gumbiner BM. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 1996; 84: 345–57.

Easwaran V, Lee SH, Inge L, et al. {β}-Catenin regulates vascular endothelial growth factor expression in colon cancer. Cancer Res 2003; 63: 3145–53.

Gilles C, Polette M, Mestdagt M, et al. Transactivation of vimentin by β-catenin in human breast cancer cells. Cancer Res 2003; 63: 2658–64.

King BL, Tsai SC, Gryga ME, et al. Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization. Clin Cancer Res 2003; 9: 1509–16.

Tan PH, Lui WO, Ong P, Lau LC, Tao M, Chong Y. Cytogenetic analysis of invasive breast cancer: a study of 27 Asian patients. Cancer Genet Cytogenet 2000; 121: 61–6.

Tirkkonen M, Tanner M, Karhu R, Kallioniemi A, Isola J, Kallioniemi OP. Molecular cytogenetics of primary breast cancer by CGH. Genes Chromosomes Cancer 1998; 21: 177–84.

Watson MB, Bahia H, Ashman JN, et al. Chromosomal alterations in breast cancer revealed by multicolour fluorescence in situ hybridization. Int J Oncol 2004; 25: 277–83.

Graziano F, Humar B, Guilford P. The role of the E-cadherin gene (CDH1) in diffuse gastric cancer susceptibility: from the laboratory to clinical practice. Ann Oncol 2003; 14: 1705–13.

Brooks-Wilson AR, Kaurah P, Suriano G, et al. Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. J Med Genet 2004; 41: 508–17.

Brinck U, Jacobs S, Neuss M, et al. Diffuse growth pattern affects E-cadherin expression in invasive breast cancer. Anticancer Res 2004; 24: 2237–42.

Palacios J, Sarrio D, Garcia-Macias MC, Bryant B, Sobel ME, Merino MJ. Frequent E-cadherin gene inactivation by loss of heterozygosity in pleomorphic lobular carcinoma of the breast. Mod Pathol 2003; 16: 674–8.

Roylance R, Droufakou S, Gorman P, et al. The role of E-cadherin in low-grade ductal breast tumourigenesis. J Pathol 2003; 200: 53–8.

Hatsell S, Rowlands T, Hiremath M, Cowin P. β-Catenin and Tcfs in mammary development and cancer. J Mammary Gland Biol Neoplasia 2003; 8: 145–58.

Campbell RJ, Pignatelli M. Molecular histology in the study of solid tumours. Mol Pathol 2002; 55: 80–2.