Tumor‐like Cerebral Perivasculitis in a Pediatric Patient with Systemic Lupus Erythematosus

The Kaohsiung Journal of Medical Sciences - Tập 24 - Trang 218-222 - 2008
Ching-Hua Huang1, Chih-Hsing Hung2,3, Yu-Te Chu3, Yi-Ming Hua4
1Department of Pediatrics, Yuan's General Hospital, Taiwan
2Department of Pediatrics, Faculty of Pediatrics, College of Medicine, Kaohsiung Medical University, Taiwan
3Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
4Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

Tóm tắt

Nervous system manifestations are present in up to 70% of patients with systemic lupus erythematosus (SLE). The spectrum of clinical symptoms varies widely, from severe, life‐threatening symptoms at presentation, such as transverse myelitis, to symptoms of more subtle and subclinical abnormalities of neurocognitive function. We report the case of a 14‐year‐old patient with SLE and lupus nephritis under regular steroid therapy, who had a sudden onset of consciousness change. Brain magnetic resonance imaging showed a huge mass lesion. After surgical decompression and corticosteroid pulse therapy, the patient's neurologic symptoms improved dramatically. Brain biopsy revealed perivasculitis of the brain with marked perivascular infiltration of eosinophils, macrophages, and neutrophils. Microhemorrhage was also evident. The patient recovered without obvious neurologic sequelae.

Tài liệu tham khảo

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Thông tin xuất bản

The Kaohsiung Journal of Medical Sciences

Tập 24

218-222

Thông tin tác giả