Tropical summer induces DNA fragmentation in boar spermatozoa: implications for evaluating seasonal infertility

Reproduction, Fertility and Development - Tập 31 Số 3 - Trang 590 - 2019
Santiago T. Peña1,2,3, Felicity Stone2, Bruce Gummow3,4, A. J. Parker5, Damien B.B.P. Paris6,2
1College of Veterinary Medicine, Visayas State University, Baybay City, Leyte, Philippines.
2Discipline of Biomedical Science, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Qld 4811, Australia.
3Discipline of Veterinary Science, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Qld 4811, Australia.
4Faculty of Veterinary Science, University of Pretoria, Onderstepoort 0110, South Africa
5College of Food, Agricultural and Environmental Sciences, Ohio State University, Wooster, OH 44691, USA.
6Centre for Tropical Environmental and Sustainability Science, James Cook University, Townsville, Qld 4811, Australia.

Tóm tắt

Summer infertility continues to undermine pig productivity, costing the pig industry millions in annual losses. The boar’s inefficient capacity to sweat, non-pendulous scrotum and the extensive use of European breeds in tropical conditions, can make the boar particularly vulnerable to the effects of heat stress; however, the link between summer heat stress and boar sperm DNA damage has not yet been demonstrated. Semen from five Large White boars was collected and evaluated during the early dry, late dry and peak wet seasons to determine the effect of seasonal heat stress on the quality and DNA integrity of boar spermatozoa. DNA damage in spermatozoa during the peak wet was 16-fold greater than during the early dry and nearly 9-fold greater than during the late dry season. Sperm concentration was 1.6-fold lower in the peak wet than early dry whereas no difference was found across several motility parameters as determined by computer-assisted sperm analysis. These results demonstrate that tropical summer (peak wet season) induces DNA damage and reduces concentration without depressing motility in boar spermatozoa, suggesting that traditional methods of evaluating sperm motility may not detect inherently compromised spermatozoa. Boar management strategies (such as antioxidant supplementation) need to be developed to specifically mitigate this problem.

Từ khóa


Tài liệu tham khảo

Ahmadi, 1999, J. Exp. Zool., 284, 696, 10.1002/(SICI)1097-010X(19991101)284:6<696::AID-JEZ11>3.0.CO;2-E

Alkmin, 2013, Theriogenology, 79, 1294, 10.1016/j.theriogenology.2013.02.026

Argenti, 2018, Andrologia

Auvigne, 2010, Theriogenology, 74, 60, 10.1016/j.theriogenology.2009.12.019

Barranco, 2013, Cryobiology, 67, 299, 10.1016/j.cryobiol.2013.09.001

Boe-Hansen, 2005, Theriogenology, 63, 2006, 10.1016/j.theriogenology.2004.09.006

Boe-Hansen, 2008, Theriogenology, 69, 728, 10.1016/j.theriogenology.2007.12.004

Boma, 2006, Onderstepoort J. Vet. Res., 73, 229

Brahem, 2011, Urology, 78, 792, 10.1016/j.urology.2011.05.049

Broekhuijse, 2012a, J. Anim. Sci., 90, 779, 10.2527/jas.2011-4311

Broekhuijse, 2012b, Theriogenology, 77, 1466, 10.1016/j.theriogenology.2011.11.016

Brzezińska-Ślebodzińska, 1995, Biol. Trace Elem. Res., 47, 69, 10.1007/BF02790102

Cameron, 1980, J. Reprod. Fertil., 59, 173, 10.1530/jrf.0.0590173

Carrell, 2003, Arch. Androl., 49, 49, 10.1080/01485010290099390

Cerolini, 2001, Reproduction, 121, 395, 10.1530/rep.0.1210395

Deshmukh, 2011, Epigenetics, 6, 177, 10.4161/epi.6.2.13519

Didion, 2009, J. Androl., 30, 655, 10.2164/jandrol.108.006254

Dobrinski, 1994, J. Reprod. Fertil., 101, 531, 10.1530/jrf.0.1010531

Dubé, 2004, Theriogenology, 62, 874, 10.1016/j.theriogenology.2003.12.006

Egbunike, 1980, Int. J. Biometeorol., 24, 129, 10.1007/BF02253800

Einarsson, 2008, Acta Vet. Scand., 50, 48, 10.1186/1751-0147-50-48

Eriksson, 2000, Anim. Reprod. Sci., 63, 205, 10.1016/S0378-4320(00)00171-8

Evenson, 1999, Reprod. Fertil. Dev., 11, 1, 10.1071/RD98023

Evenson, 2016, Anim. Reprod. Sci., 169, 56, 10.1016/j.anireprosci.2016.01.017

Evenson, 2006, Theriogenology, 65, 979, 10.1016/j.theriogenology.2005.09.011

Evenson, 2009, Reprod. Fertil. Dev., 21, 212, 10.1071/RDv21n1Ab228

Fernandes, 2008, Theriogenology, 70, 1560, 10.1016/j.theriogenology.2008.07.005

Flowers, 1997, J. Reprod. Fertil. Suppl., 52, 67

França, 1998, Tissue Cell, 30, 573, 10.1016/S0040-8166(98)80038-4

França, 2005, Theriogenology, 63, 300, 10.1016/j.theriogenology.2004.09.014

Gadea, 2004, Reprod. Domest. Anim., 39, 303, 10.1111/j.1439-0531.2004.00513.x

García-Macías, 2007, Int. J. Androl., 30, 88, 10.1111/j.1365-2605.2006.00723.x

Gorczyca, 1993, Exp. Cell Res., 207, 202, 10.1006/excr.1993.1182

Gosálvez, 2011, Mol. Reprod. Dev., 78, 951, 10.1002/mrd.21394

Grant, 1994, J. Reprod. Fertil., 100, 477, 10.1530/jrf.0.1000477

Hancock, 1959, Vet. Rec., 71

Heitman, 1984, Anim. Sci., 38, 129, 10.1017/S0003356100041441

Henkel, 2004, Fertil. Steril., 81, 965, 10.1016/j.fertnstert.2003.09.044

Henkel, 2010, Andrologia, 42, 305, 10.1111/j.1439-0272.2009.01002.x

Hennessy, 1984, Aust. Vet. J., 61, 212, 10.1111/j.1751-0813.1984.tb05991.x

Holt, 1997, J. Androl., 18, 312, 10.1002/j.1939-4640.1997.tb01925.x

Huynh, 2007, Asian J. Agric. Dev., 4, 69

Ingram, 1965, Nature, 207, 415, 10.1038/207415a0

Kilkenny, 2010, PLoS Biol., 8, 10.1371/journal.pbio.1000412

Kishikawa, 1999, Biol. Reprod., 61, 809, 10.1095/biolreprod61.3.809

Love, 1981, Vet. Rec., 109, 407, 10.1136/vr.109.18.407

Love, 1998, Theriogenology, 50, 955, 10.1016/S0093-691X(98)00199-X

McNitt, 1970, Int. J. Biometeorol., 14, 373, 10.1007/BF01462914

Mortimer, 2000, J. Androl., 21, 515, 10.1002/j.1939-4640.2000.tb02116.x

Oestrup, 2009, Reprod. Domest. Anim., 44, 39, 10.1111/j.1439-0531.2009.01482.x

Pacey, 2010, Hum. Fertil., 13, 189, 10.3109/14647273.2010.531883

Parrish, 2017, Mol. Reprod. Dev., 84, 969, 10.1002/mrd.22841

Paterson, 1978, Aust. J. Exp. Agric., 18, 698, 10.1071/EA9780698

Paul, 2008, Reproduction, 136, 73, 10.1530/REP-08-0036

Peña, 2015, Theriogenology, 83, 1502, 10.1016/j.theriogenology.2015.01.033

Peña, 2017, Anim. Prod. Sci., 57, 1975, 10.1071/AN16079

Pérez-Crespo, 2008, Mol. Reprod. Dev., 75, 40, 10.1002/mrd.20759

Petrocelli, 2015, Rev. Bras. Zootec., 44, 1, 10.1590/S1806-92902015000100001

Pingali, 2007, Food Policy, 32, 281, 10.1016/j.foodpol.2006.08.001

Prunier, 1997, Livest. Prod. Sci., 52, 123, 10.1016/S0301-6226(97)00137-1

Pursel, 1975, J. Anim. Sci., 40, 99, 10.2527/jas1975.40199x

Qiu, 2012, J. Assist. Reprod. Genet., 29, 185, 10.1007/s10815-011-9688-4

Roca, 2015, Reprod. Domest. Anim., 50, 48, 10.1111/rda.12530

Rockett, 2001, Biol. Reprod., 65, 229, 10.1095/biolreprod65.1.229

Rybar, 2004, Vet. Med. (Praha), 49, 1, 10.17221/5668-VETMED

Sailer, 1997, J. Androl., 18, 294, 10.1002/j.1939-4640.1997.tb01922.x

Sarlós, 2011, Acta Vet. Hung., 59, 257, 10.1556/AVet.2011.007

Satake, 2006, J. Exp. Biol., 209, 1560, 10.1242/jeb.02136

Serafini, 2016, J. Equine Vet. Sci., 43, S65, 10.1016/j.jevs.2016.06.030

Simon, 2011, Syst Biol Reprod Med, 57, 133, 10.3109/19396368.2011.553984

Simon, 2013, Reprod. Biomed. Online, 26, 68, 10.1016/j.rbmo.2012.09.019

Sonderman, 2008, Theriogenology, 70, 1380, 10.1016/j.theriogenology.2008.08.009

Stone, 1982, Anim. Reprod. Sci., 4, 283, 10.1016/0378-4320(82)90043-4

Stone, 1984, Anim. Reprod. Sci., 7, 391, 10.1016/0378-4320(84)90041-1

St-Pierre, 2003, J. Dairy Sci., 86, E52, 10.3168/jds.S0022-0302(03)74040-5

Sumena, 2010, J. Vet. Anim. Sci. (Lahore), 6, 128

Sutovsky, 2015, Reprod. Domest. Anim., 50, 11, 10.1111/rda.12554

Thom, 1959, Weatherwise, 12, 57, 10.1080/00431672.1959.9926960

Tramontano, 2000, Mol. Hum. Reprod., 6, 575, 10.1093/molehr/6.7.575

Tsakmakidis, 2010, J. Vet. Sci., 11, 151, 10.4142/jvs.2010.11.2.151

van Zelst, 1995, Reprod. Fertil. Dev., 7, 1117, 10.1071/RD9951117

Vega, 2010, Philipp. J. Vet. Anim. Sci., 36, 63

Venkatesh, 2011, Reprod. Sci., 18, 1005, 10.1177/1933719111401662

Vyt, 2008, Vlaams Diergeneeskundig Tijdschrift, 77, 291, 10.21825/vdt.87221

Waberski, 2011, Theriogenology, 75, 337, 10.1016/j.theriogenology.2010.09.004

Wettemann, 1976, J. Anim. Sci., 42, 664, 10.2527/jas1976.423664x

Wettemann, 1979, J. Anim. Sci., 49, 1501, 10.2527/jas1979.4961501x

Zasiadczyk, 2015, Theriogenology, 83, 1287, 10.1016/j.theriogenology.2015.01.015

Thông tin
Thông tin xuất bản

Reproduction, Fertility and Development

Tập 31 Số 3

590

Thông tin tác giả