Chỉ số triglyceride glucose là một dấu ấn hữu ích để dự đoán bệnh động mạch vành tiềm ẩn khi không có các yếu tố nguy cơ truyền thống
Tóm tắt
Các sự kiện tim mạch do xơ vữa (CV) thường xảy ra ở những cá nhân có gánh nặng nguy cơ CV thấp. Nghiên cứu này đánh giá khả năng của chỉ số triglyceride glucose (TyG) trong việc dự đoán bệnh động mạch vành (CAD) tiềm ẩn ở những cá nhân không có triệu chứng và không có các yếu tố nguy cơ CV truyền thống (CVRF).
Nghiên cứu hồi cứu, cắt ngang và quan sát này đánh giá mối liên quan giữa chỉ số TyG và CAD ở 1250 cá nhân không có triệu chứng (52.8 ± 6.5 năm, 46.9% nam giới) không có các CVRF truyền thống (được định nghĩa là huyết áp tâm thu/tâm trương ≥ 140/90 mmHg; glucose lúc đói ≥126 mg/dL; cholesterol toàn phần ≥240 mg/dL; cholesterol lipoprotein mật độ thấp ≥160 mg/dL; cholesterol lipoprotein mật độ cao < 40 mg/dL; chỉ số khối cơ thể ≥25.0 kg/m2; hút thuốc hiện tại; và tiền sử bệnh lý có xơ vữa, tiểu đường, hoặc rối loạn lipid máu). CAD được định nghĩa là sự hiện diện của bất kỳ mảng bám động mạch nào trên chụp động mạch vi tính vành. Các tham gia được chia thành ba nhóm dựa trên tertile chỉ số TyG.
Tỷ lệ CAD tăng lên với việc tăng tertile chỉ số TyG (nhóm I: 14.8% so với nhóm II: 19.3% so với nhóm III: 27.6%;
Từ khóa
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