Transferrin binding of bone marrow cells and metabolic activity of erythrocytes after 5 Gy irradiation

Bioscience Reports - 1992
Pilar Sancho1, Elvira Cuenllas2, Soledad Gaitán2, C Tejero2
1Departmento de Bioquímica y Biologia Molecular, Universidad de Alcalá, 28871 Alcalá de Henares, Madrid, Spain
2Departamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Universidad Complutense de Madrid, Spain.

Tóm tắt

The effect of total body irradiation (5 Gy) on functional mouse erythroid lineage has been studied. The transferrin binding capacity by bone marrow cells and the activity of glycolytic regulatory enzymes and intracellular levels of 2,3 bisphosphoglycerate in peripheral blood erythrocytes have been determined. Results obtained along one year post-irradiation period suggest a complete recovery in the erythroid cell lineage with respect to the biological endpoints investigated.

Từ khóa


Tài liệu tham khảo

Hendry, J. H. (1985)Radiotherapy and Oncology 3:331?338.

Testa, N. G., Hendry, J. H. & Molineaux, G. (1985)Anticancer Res. 5:101?110.

Gaitan, S., Cuenllas, E., Sancho, P., Bueren, J. and Tejero, C. (1991) 9th International Congress of Radiation Research. Toronto, 7?12 July 1991.

Taetle, R. (1990)Exp. Hematol. 18:360?365.

Mendieta, J., Herraez, A., Sancho, P. and Luque, J. (1989)Biosci. Rep. 9: 541?548.

Harvey, J. W. (1989) In: ?Clinical Biochemistry of Domestic Animals? ed Kaneko J. J. Academic Press, Inc. pp. 206?213.

Scatchard, G. (1949)Ann. NY Acad. Sci. 51:660?672.

Kermode, J. C. (1989)Biochem. Pharmacol. 38:2053?2060.

Mcleod, R. A., Jonas, R. E. E. and Roberts, E. (1963)Can. J. Biochem. Physiol. 41: 1971?1981.

Layzer, R. B. (1975) In: ?Methods in Enzymology? vol 52 ed. Wood, W. A. Academic Press, New York. 110?114.

Bücher, T. and Pfleiderer, G. (1955) In: ?Methods in Enzymology? Vol 1 eds. Colowick, S. and Kaplan, N. O. Academic Press, New York. pp 345?440.

Rose, Z. B. and Liebowitz, J. (1970)Anal. Biochem. 35:177?182.

Van Kampen, Z. J. and Zjilstra, W. G. (1961)Clin. Chim. Acta 6:538?544.

Lowry, O. M., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951).J. Biol. Chem. 193:265?275.

Nunez, M. T., Glass, J., Fischer, S., Lavidor, L. M., Lenk, E. M. & Robinson, S. M. (1977)Br. J. Haematol. 36:519?526.

Shannon, K. M., Larrick, J. W., Fulcher, S. A., Burck, K. B., Pacely, J., Davis, J. C. & Ring, D. B. (1986)Blood 67:1531?1638.

Cotner, T., Das Gupta, A., Papayannopoulou, Th. & Stamatoyannopoulos, G. (1989)Blood 73:214?221.

Iacopeta, B. J., Morgan, E. H. & Yeoh, G. C. T. (1982)Biochim. Biophys. Acta,687: 204?210.

Vogel, W., Bomford, A., Young, S. & Williams, R. (1987)Blood 69: 264?270.

Yang, F., Friechichs, W. E., Buchanan, J. M., Herbert, D. C., Weaker, F. J.. Brock, J. M. & Bowman, B. H. (1990)Mech. Ageing Dev. 56:187?197.

Petkan, A. (1988)Mol. Cell. Biochem. 84:133?140.

Etiemble, J., Bernard, J. F., Picat, C., Belpomme, D. & Boivin, P. (1979)Brit. J. Haematol. 42:391?398.

Thông tin
Thông tin xuất bản

Bioscience Reports

Thông tin tác giả