Tranilast directly targets NLRP 3 to treat inflammasome‐driven diseases

EMBO Molecular Medicine - Tập 10 Số 4 - 2018
Yi Huang1,2, Hua Jiang2, Yun Chen3, Xiaqiong Wang2, Yanqing Yang4, Jin‐Hui Tao5, Xianming Deng3, Gaolin Liang6, Huafeng Zhang1,2, Wei Jiang2, Rongbin Zhou1,2
1Innovation Center for Cell Signaling Network University of Science and Technology of China Hefei China
2Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease CAS Center for Excellence in Molecular Cell Sciences Hefei National Laboratory for Physical Sciences at Microscale University of Science and Technology of China Hefei China
3State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian, China
4Department of Clinical Laboratory, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China
5Department of Rheumatology & Immunology The First Affiliated Hospital of University of Science and Technology of China Hefei Anhui China
6CAS Key Laboratory of Soft Matter Chemistry; Department of Chemistry, University of Science and Technology of China, Hefei, China

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