Tissue factor at the crossroads of coagulation and radiation response in glioblastoma

Jeon, 2023, Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling, Cancer Cell, 41, 1480, 10.1016/j.ccell.2023.06.007 Grover, 2018, Tissue factor: an essential mediator of hemostasis and trigger of thrombosis, Arterioscler Thromb Vasc Biol, 38, 709, 10.1161/ATVBAHA.117.309846 Tawil, 2021, Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles, Blood Adv, 5, 1682, 10.1182/bloodadvances.2020002998 Wang, 2012, Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer, Blood, 119, 5543, 10.1182/blood-2012-01-402156 Hisada, 2017, Human pancreatic tumors grown in mice release tissue factor-positive microvesicles that increase venous clot size, J Thromb Haemost, 15, 2208, 10.1111/jth.13809 Verheij, 1995, The effect of ionizing radiation on endothelial tissue factor activity and its cellular localization, Thromb Haemost, 73, 894, 10.1055/s-0038-1653889 Szotowski, 2007, Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation- and cytokine-induced endothelial cells, Cardiovasc Res, 73, 806, 10.1016/j.cardiores.2006.12.018 Eisenreich, 2008, Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and paclitaxel, Int Immunopharmacol, 8, 307, 10.1016/j.intimp.2007.06.005 Baskar, 2012, Cancer and radiation therapy: current advances and future directions, Int J Med Sci, 9, 193, 10.7150/ijms.3635 Zelaya, 2018, Tissue factor at the crossroad of coagulation and cell signaling, J Thromb Haemost, 16, 1941, 10.1111/jth.14246 Green, 2010, Role of thrombin as a tumor growth factor, Cell Cycle, 9, 656, 10.4161/cc.9.4.10729 Steinbrecher, 2010, Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin αMβ2 engagement of fibrinogen, Cancer Res, 70, 2634, 10.1158/0008-5472.CAN-09-3465 Sharma, 2021, Fibrinogen activates focal adhesion kinase (FAK) promoting colorectal adenocarcinoma growth, J Thromb Haemost, 19, 2480, 10.1111/jth.15440 Morrissey, 1988, Monoclonal antibody analysis of purified and cell-associated tissue factor, Thromb Res, 52, 247, 10.1016/0049-3848(88)90084-9 Hu, 1999, Targeting tumor vasculature endothelial cells and tumor cells for immunotherapy of human melanoma in a mouse xenograft model, Proc Natl Acad Sci U S A, 96, 8161, 10.1073/pnas.96.14.8161 Gogia, 2023, Antibody–drug conjugates: a review of approved drugs and their clinical level of evidence, Cancers, 15, 3886, 10.3390/cancers15153886 Breij, 2014, An antibody-drug conjugate that targets tissue factor exhibits potent therapeutic activity against a broad range of solid tumors, Cancer Res, 74, 1214, 10.1158/0008-5472.CAN-13-2440 Koga, 2015, Antitumor effect of antitissue factor antibody-MMAE conjugate in human pancreatic tumor xenografts, Int J Cancer, 137, 1457, 10.1002/ijc.29492 Zhang, 2017, Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma, Oncotarget, 8, 59086, 10.18632/oncotarget.19175 Theunissen, 2018, Treating tissue factor-positive cancers with antibody-drug conjugates that do not affect blood clotting, Mol Cancer Ther, 17, 2412, 10.1158/1535-7163.MCT-18-0471 Coleman, 2021, Efficacy and safety of tisotumab vedotin in previously treated recurrent or metastatic cervical cancer (innovaTV 204/GOG-3023/ENGOT-cx6): a multicentre, open-label, single-arm, phase 2 study, Lancet Oncol, 22, 609, 10.1016/S1470-2045(21)00056-5 Abounader, 2021, The blood-brain barrier limits the therapeutic efficacy of antibody-drug conjugates in glioblastoma, Neuro Oncol, 23, 1993, 10.1093/neuonc/noab223 Greene, 2010, Animal Models Subcommittee of the Scientific And Standardization Committee of the ISTH AMSotSASCOT. Towards a standardization of the murine tail bleeding model, J Thromb Haemost, 8, 2820, 10.1111/j.1538-7836.2010.04084.x Wang, 2009, Levels of microparticle tissue factor activity correlate with coagulation activation in endotoxemic mice, J Thromb Haemost, 7, 1092, 10.1111/j.1538-7836.2009.03448.x Wen, 2020, Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions, Neuro Oncol, 22, 1073, 10.1093/neuonc/noaa106 Riedl, 2017, Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism, Blood, 129, 1831, 10.1182/blood-2016-06-720714