Tissue engineering: strategies, stem cells and scaffolds

Journal of Anatomy - Tập 213 Số 1 - Trang 66-72 - 2008
Daniel J. Howard1, Lee Buttery1, Kevin M. Shakesheff1, Scott J. Roberts1
1Wolfson Centre for Stem Cells, Tissue Engineering and Modelling, Centre for Biomolecular Science, School of Pharmacy, University of Nottingham, UK

Tóm tắt

AbstractTissue engineering scaffolds are designed to influence the physical, chemical and biological environment surrounding a cell population. In this review we focus on our own work and introduce a range of strategies and materials used for tissue engineering, including the sources of cells suitable for tissue engineering: embryonic stem cells, bone marrow‐derived mesenchymal stem cells and cord‐derived mesenchymal stem cells. Furthermore, we emphasize the developments in custom scaffold design and manufacture, highlighting laser sintering, supercritical carbon dioxide processing, growth factor incorporation and zoning, plasma modification of scaffold surfaces, and novel multi‐use temperature‐sensitive injectable materials.

Từ khóa


Tài liệu tham khảo

10.1002/adma.200400838

Ashton BA, 1980, Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo, Clin Orthop Relat Res, 151, 294

10.1016/S0140-6736(06)68438-9

Barry JJA, 2006, Using a core‐sheath distribution of chemistry through tissue engineering scaffolds to control cell ingress, Advanced Materials, 18, 1

10.1089/ten.2004.10.1518

10.1056/NEJM199410063311401

10.1002/jor.1100160202

10.1634/stemcells.2006-0598

10.1089/107632700300003323

10.1016/j.transproceed.2006.02.084

10.1359/jbmr.1999.14.7.1115

10.1002/bit.21343

10.1387/ijdb.052107cd

10.1089/ten.2006.0342

10.1002/jbm.820270104

Friedenstein AJ, 1966, Osteogenesis in transplants of bone marrow cells, J Embryol Exp Morphol, 16, 381

10.1073/pnas.0508895103

Hamilton L, 2006, Development of an injectable scaffold for application in regenerative medicine to deliver stem cells and growth factors, J Pharm Pharmacol, 58, A52

10.1002/jps.20002

10.1016/8756-3282(92)90363-2

10.2217/17460751.1.6.809

10.1634/stemcells.2005-0481

10.1002/bit.21446

10.1016/j.actbio.2006.12.006

10.1007/BF02983804

10.1016/S0006-291X(02)02561-5

10.1073/pnas.0400164101

10.1634/stemcells.2004-0304

10.1016/j.bbrc.2006.10.187

10.1016/j.cellbi.2006.02.007

10.1126/science.8493529

10.1182/blood-2003-05-1670

10.1002/1097-4652(200010)185:1<98::AID-JCP9>3.0.CO;2-1

10.1002/jor.20430

10.1042/cs0940549

10.1002/jor.1100090504

10.1302/0301-620X.81B6.9343

10.1111/j.1582-4934.2004.tb00272.x

10.1182/blood.V78.1.55.55

10.1089/153623003322234759

10.1007/s00441-003-0762-9

10.1007/s10856-006-0443-9

10.2217/17460751.1.5.685

10.1016/j.jconrel.2004.07.017

10.1089/ten.2005.11.1876

10.1016/S8756-3282(01)00617-2

Thông tin
Thông tin xuất bản

Journal of Anatomy

Tập 213 Số 1

66-72

Thông tin tác giả