Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss

Science Signaling - Tập 10 Số 498 - 2017
Yanhong Li1,2,3, Jiayuan Zhang4, Di Zhang1,2,3, Xi Hong5, Tao Yu2, Songcun Wang1,2,3, Yuanyuan Xu2, Hailan Piao2, Weijie Yin4, Min Yu2, Zhang Yin2, Qiang Fu2, Da‐Jin Li1,2,3, Xing Chang4, Meirong Du1,2,3
1Key Laboratory of Reproduction Regulation of National Population and Family Planning Commission, Shanghai Institute of Planned Parenthood Research, Institute of Reproduction and Development, Fudan University, Shanghai 200032, China
2Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai 200011, China
3Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai 200011, China
4Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine and Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
5Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China

Tóm tắt

A subset of natural killer cells suppresses the mother’s immune system to protect the fetus.

Từ khóa


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Tập 10 Số 498

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