Therapeutic Potential of Riboflavin, Niacin and Ascorbic Acid on Carbohydrate Metabolizing Enzymes in Secondary Endometrial Carcinoma Bearing Rats

Molecular and Cellular Biochemistry - Tập 288 Số 1-2 - Trang 73-78 - 2006
Sengodan Sundravel1, Palanivelu Shanthi2, Panchanatham Sachdanandam3
1Department of Medical Biochemistry, Dr. ALM. Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai, 600 113, India
2Department of Pathology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113, India
3Department of Medical Biochemistry, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600 113, India

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Tài liệu tham khảo

Rose PG: Endometrial carcinoma. New Engl J Med 335: 640–649, 1996

Daniel Y, Inbar M, Bar-Am A, Renben Peyser MK, Lessing JB: The effects of tamoxifen treatment on the endometrium. Fertility and Sterility 65: 1083–1089, 1996

Han X, Liehr JG: Induction of covalent DNA adducts in Rodents by tamoxifen. Cancer Res 52: 1360–1363, 1992

Yager JD: Molecular mechanisms of estrogen carcinogenesis. Annu Rev Pharmacol Toxicol 36: 203–232, 1996

Murray M: Encyclopedia of nutritional supplements. Rocklin CA: Prima Publishing, 1996

Rivlin RS: In: Present knowledge in Nutrition: International Life Sciences Institute Press, Washington, DC, 1996, pp. 167–173

Garrison R, Somer E: The Nutrition desk reference. New Canaan, CT: Keats Publishing, 1995, pp. 133–140

Yan Q, Briehl M, Crowley CL, Payne CM, Bernstein H, Ernstein C: The NAD+ precursors, glyceraldehyde-3-phosphate dehydrogenase and glucose-6-phosphate dehydrogenase mRNA in jurkat cells. Biochem Biophys Res Commun 255: 133–136, 1999

Hageman GJ, Stierum RH: Niacin, Poly (ADP-ribose) Polymerase-1 and genomic stability. Mutat Res 475: 45–56, 2001

Jacobson EL, Shieh WM, Huang AC: Mapping the role of NAD metabolism in prevention and treatment of carcinogenesis. Mol Cell Biochem 193: 69–74, 1999

Spronck JC, Kirkland JB: Niacin deficiency increases spontaneous and etoposide-induced chromosomal instability in rat bone marrow cells in vivo. Mutat Res 508: 83–97, 2002

Frei B, England L, Ames BN: Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 86: 6377–6381, 1989

Sharma M, Slocum HK: Prevention of quinone-mediated DNA arylation by antioxidants. Biochem Biophys Res Commun 262: 769–774, 1999

Liehr JG, Roy D, Gladek A: Mechanism of inhibition of estrogen induced renal carcinogenesis in male Syrian hamsters by vitamin C. Carcinogenesis (Lond.) 10: 1983–1988, 1989

Bendich A, Vitamin C: In: Vitamin C in health and disease: New York: Marcel Dekker Inc., 1997, pp. 367–379

Sujatha V, Muthumanickam V, Rani G, Sachdanandam P: Effect of Semecarpus anacardium Linn. nut extract on glucose metabolizing enzymes in experimentally induced mammary carcinoma in rats. J Pharm Pharmacol (Suppl) 51: 241, 1999

Hemminki K, Rajaniemi H, Lindahl B, Moberger B: Tamoxifen-induced DNA adducts in endometrial samples from Breast cancer patients. Cancer Res 56: 4374–4377, 1996

Dollery C: In: Therapeutic drugs: Harcourt Brace and Company Limited, Churchill Livingstone, 1999a, pp. R24–R25

Zempleni J, Galloway JR, McCormick DB: Pharmacokinetics of orally and intravenously administered riboflavin in healthy human. Am J Clin Nutr 63: 54–66, 1996

Dollery C: In: Therapeutic drugs: Harcourt Brace and Company Limited, Churchill Livingstone, 1999b, pp. N59–N61

Dipalma JR, Thayer WS: Use of niacin as a drug. Annu Rev Nutr 11: 169–187, 1991

Rader JI, Calvert RJ, Hathcock JN: Hepatic toxicity of unmodified and time-release preparations of niacin. Am J Med 92: 77–81, 1992

Vasavi H, Thangaraju M, Ramesh Babu J, Sachdanandam P: The salubrious effects of ascorbic acid on cyclophosphamide instigated lipid abnormalities in Fibrosarcoma bearing rats. Cancer Biochem Biophys 16: 71–83, 1998

Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with Folin phenol reagent. J Biol Chem 193: 265–275, 1951

Fiske CH, Subbarow Y: The calorimetric determination of phosphorus. J Biol Chem 66: 375–400, 1925

Brandstrup N, Kirk JE, Bruni C: The hexokinase and phosphoglucoisomerase activities of aortic and pulmonary artery tissue inindividuals of various ages. J Gerontol 12: 166–171,1957

King J: In: Practical Clinical Enzymology: D. Van Nostrand: London, 1965a; pp. 121–138

Horrocks JE, Ward J, King J: A routine method for the determination of phosphoglucoisomerase activity in body fluid. J Clin Pathol 16: 248–252, 1963

King J: In: Practical Clinical Enzymology: D.Van Nostrand: London, 1965b; pp. 191–208

Gancedo JM, Gancedo C: Fructose-1, 6-diphosphatase, phosphofructokinase and glucose-6-phosphate dehydrogenase in fermenting and nonfermenting yeast. Arch Microbiol 76: 132–138, 1971

Mazurek S, Boschek CB, Hugoc F, Eigenbrodt E: Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin Cancer Biol 15: 300–308, 2005

Hatzivassiliou G, Zhao F, Bauer DE, Andreadis C, Shaw AN, Dhanak D, Hingorani SR, Tuveson DA, Thompson1 CB: ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 8: 311–321. 2005

Harada T, Nagasu M, Tsuboi I, Koshinaga M, Kanno H, Aizawa S: Cyclic polylactate inhibited growth of cloned leukemic cells through reducing glycolytic enzyme activities. Oncol Rep 14: 501–505. 2005

Simaga S, Osmak M, Babic D, Sprem M, Vukelic B, Abramic M: Quantitative biochemical analysis of lactate dehydrogenase in human ovarian tissues: Correlation with tumor grade. Int J Gynecol Cancer 15: 438–444, 2005

Chowdhury SKR, Gemin A, Singh G: High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphate-dependent ROS production in prostate cancer cell lines. Biochem Biophys Res Commun 333: 1139–1145, 2005

Arora KK, Pedersen PL: Functional significance of mitochondrial bound hexokinase in tumour cell metabolism. J Biol Chem 263: 17422–17428, 1988

Parry DM, Pedersen PL: Intracellular localization and properties of particulate hexokinase in the Novikoff ascites tumour. J Biol Chem 258: 10904–10912, 1983

Mathupale SP, Rempel A, Pedersen PL: Aberrant glycolytic metabolism of cancer cells: A remarkable co-ordination of genetic, transcriptional, post translational and mutational events that lead to a critical role for type II hexokinase. J Bioenerg Biomembr 29: 339–343, 1997

Paul R, Iohansson R, Kellokumpu-Lehtinen PL, Soderstrom KV, Kangas L: Tumour localization with 18 F-2 Fluoro-2 deoxy D glucose: Comparative autoradiography, glucose-6-phosphatase histochemistry and histology of renally implanted sarcoma of the rat. Res Exp Med 185: 87–95, 1985

Graham MM, Spence AM, Muzi M, Abott GL: Deoxyglucose kinetics in a rat brain tumor. J Cereb Blood Flow Metab 9: 315–322, 1989

Hennipman A, Van Oirschot B, Smits J, Rijsken G, Staal GE: Heterogenicity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer. Tumour Biol 9: 178–189, 1988

Campbell DM, King EJ: Colorimetric determination of glucose in 20 microliters of blood. J Clin Pathol 16: 173–174, 1963

Parveen V, Sharma DC, Shastri KD: A clinico-biochemical study of phosphohexose-isomerase, aliesterate and sulphydryl group in 25 normal and 35 cancer patients. Ind J Cancer 43: 448–456, 1974

Weber G, Morris HP: Comparative biochemistry of hepatomas I carbohydrate enzymes in Morris hepatoma 5123. Cancer Res 21: 933–937, 1961

Weber G, Cantero A: Comparison of carbohydrate metabolism in normal and neoplastic liver enzyme studies. Acta Unio Int Contra Cancrum 16: 1002–1011, 1960